Multicenter Prospective Cohort Study of the Diagnostic Yield and Patient Experience of Multiplex Gene Panel Testing For Hereditary Cancer Risk
Idos G, Kurian A, Ricker C, Sturgeon D, Culver J, Kingham K, Koff R, Chun N, Rowe-Teeter C, Lebensohn A, Levonian P, Lowstuter K, Partynski K, Hong C, Mills M, Petrovchich I, S. C, Hartman A, Allen B, Wenstrup R, Lancaster J, Brown K, Kidd J, Evans B, Mukherjee B, McDonnell K, Ladabaum U, Ford J, Gruber S. Multicenter Prospective Cohort Study of the Diagnostic Yield and Patient Experience of Multiplex Gene Panel Testing For Hereditary Cancer Risk. JCO Precision Oncology 2019, 3: po.18.00217. PMID: 34322651, PMCID: PMC8260917, DOI: 10.1200/po.18.00217.Peer-Reviewed Original ResearchMultiplex gene panel testProspective cohort studyGene panel testingPatient experiencePathogenic variantsDiagnostic yieldCohort studyNorris Comprehensive Cancer CenterHereditary cancer riskSocioeconomically diverse cohortComprehensive cancer centerPost-test surveysPanel testingCancer susceptibility genesMulticenter prospective cohort studyLos Angeles CountyUniversity of Southern California Medical CenterIdentified pathogenic variantsCancer riskSouthern California Medical CenterLess educationPatient regretProphylactic surgeryExpert clinical assessmentCalifornia Medical Center