Urinary Phthalate Metabolites and Biomarkers of Oxidative Stress in Pregnant Women: A Repeated Measures Analysis
Ferguson K, McElrath T, Chen Y, Mukherjee B, Meeker J. Urinary Phthalate Metabolites and Biomarkers of Oxidative Stress in Pregnant Women: A Repeated Measures Analysis. Environmental Health Perspectives 2014, 123: 210-216. PMID: 25402001, PMCID: PMC4348741, DOI: 10.1289/ehp.1307996.Peer-Reviewed Original ResearchConceptsUrinary phthalate metabolitesPhthalate metabolitesMono-n-butyl phthalateBiomarkers of oxidative stressBirth outcomesNested case-control study of preterm birthCase-control study of preterm birthPhthalate exposureStudy of preterm birthStudy of birth outcomesOxidative stressPopulation of pregnant womenNested case-control studyStudy population of pregnant womenAdverse birth outcomesUrine samplesMarkers of oxidative stressRepeated measures analysisHealth end pointsAssociated with significantly higher concentrationsDi(2-ethylhexyl) phthalatePreterm birthPregnant womenMono-n-butylLinear mixed modelsUrinary Phthalate Metabolite Associations with Biomarkers of Inflammation and Oxidative Stress Across Pregnancy in Puerto Rico
Ferguson K, Cantonwine D, Rivera-González L, Loch-Caruso R, Mukherjee B, Del Toro L, Jiménez-Vélez B, Calafat A, Ye X, Alshawabkeh A, Cordero J, Meeker J. Urinary Phthalate Metabolite Associations with Biomarkers of Inflammation and Oxidative Stress Across Pregnancy in Puerto Rico. Environmental Science And Technology 2014, 48: 7018-7025. PMID: 24845688, PMCID: PMC4066910, DOI: 10.1021/es502076j.Peer-Reviewed Original ResearchConceptsMono-n-butyl phthalateBiomarkers of inflammationIL-10Prospective cohort study of pregnant womenDi-2-ethylhexyl phthalate metabolitesCohort study of pregnant womenIL-6Study of pregnant womenAssociated with increased IL-6Oxidative stressUrinary phthalate metabolitesC-reactive proteinProspective cohort studyAdverse birth outcomesMetabolites of di-2-ethylhexyl phthalateOxidative stress markersPreterm birthMetabolite associationsPregnant womenMono-n-butylDi-2-ethylhexyl phthalateOxidative stress biomarkersBirth outcomesTNF-aInflammation biomarkers