2022
Biomarkers of Exposure to Phthalate Mixtures and Adverse Birth Outcomes in a Puerto Rico Birth Cohort
Cathey A, Watkins D, Rosario Z, Vélez C, Mukherjee B, Alshawabkeh A, Cordero J, Meeker J. Biomarkers of Exposure to Phthalate Mixtures and Adverse Birth Outcomes in a Puerto Rico Birth Cohort. Environmental Health Perspectives 2022, 130: 037009. PMID: 35333099, PMCID: PMC8953418, DOI: 10.1289/ehp8990.Peer-Reviewed Original ResearchConceptsSpontaneous preterm birthPreterm birthFetal sexGestational agePregnancy outcomesBirth outcomesBayesian kernel machine regressionPhthalate metabolitesRisk of early deliveryAssociated with increased odds of PTBOdds of preterm birthPhthalate mixtureReduced gestational ageIndividual phthalate metabolitesMeasures of birth weightAssociated with increased riskPhthalate metabolite mixturesAdverse birth outcomesAssociated with increased oddsPuerto Rico TestsiteEnvironmental risk scoreEarly deliveryBirth weightPregnancy cohortLongitudinal pregnancy cohort
2021
Maternal lipidomic signatures in relation to spontaneous preterm birth and large-for-gestational age neonates
Aung M, Ashrap P, Watkins D, Mukherjee B, Rosario Z, Vélez-Vega C, Alshawabkeh A, Cordero J, Meeker J. Maternal lipidomic signatures in relation to spontaneous preterm birth and large-for-gestational age neonates. Scientific Reports 2021, 11: 8115. PMID: 33854141, PMCID: PMC8046995, DOI: 10.1038/s41598-021-87472-9.Peer-Reviewed Original ResearchConceptsSpontaneous preterm birthBiomarkers of pregnancy outcomesGestational age neonatesPreterm birthAge neonatesPregnancy outcomesDegree of hydrocarbon chain saturationIncreased riskNeonatal anthropometric parametersAssociated with increased riskPlasmenyl phosphatidylethanolamineMaternal lipidomeWeeks gestationGestational ageLipidomic signatureAnthropometric parametersLiquid chromatography tandem mass spectrometryLipidomic profilesLipid metabolitesHydrocarbon chain saturationPlasma samplesBirthLogistic regressionHigh-performance liquid chromatography tandem mass spectrometryNeonates
2020
Estrogen Plus Progestin Hormone Therapy and Ovarian Cancer: A Complicated Relationship Explored.
Lee A, Wu A, Wiensch A, Mukherjee B, Terry K, Harris H, Carney M, Jensen A, Cramer D, Berchuck A, Doherty J, Modugno F, Goodman M, Alimujiang A, Rossing M, Cushing-Haugen K, Bandera E, Thompson P, Kjaer S, Hogdall E, Webb P, Huntsman D, Moysich K, Lurie G, Ness R, Stram D, Roman L, Pike M, Pearce C. Estrogen Plus Progestin Hormone Therapy and Ovarian Cancer: A Complicated Relationship Explored. Epidemiology 2020, 31: 402-408. PMID: 32028322, PMCID: PMC7584395, DOI: 10.1097/ede.0000000000001175.Peer-Reviewed Original ResearchConceptsRisk of ovarian cancerEstrogen-progestin combined therapyEstrogen-alone therapyAssociated with increased riskOvarian cancerCombination therapyRisk of ovarian cancer overallAssociated with increased risk of ovarian cancerOvarian cancer risk factorsPopulation-based case-control studyOvarian Cancer Association ConsortiumMenopausal hormone therapy useIncreased risk of endometrial cancerOvarian cancer overallRisk of endometrial cancerCancer risk factorsHistotypes of ovarian cancerRisk factorsProgestin hormone therapyMucinous ovarian cancerOvarian cancer casesIn-person interviewsHormone therapy useOvarian cancer histotypesCase-control study
2016
Urinary Concentrations of Bisphenol A and Phthalate Metabolites Measured during Pregnancy and Risk of Preeclampsia
Cantonwine D, Meeker J, Ferguson K, Mukherjee B, Hauser R, McElrath T. Urinary Concentrations of Bisphenol A and Phthalate Metabolites Measured during Pregnancy and Risk of Preeclampsia. Environmental Health Perspectives 2016, 124: 1651-1655. PMID: 27177253, PMCID: PMC5047771, DOI: 10.1289/ehp188.Peer-Reviewed Original ResearchRisk of preeclampsiaUrinary concentrations of BPAUrinary concentrations of bisphenol APhthalate metabolitesUrinary concentrationsAssociated with increased risk of preeclampsiaHazard ratioCases of preeclampsiaNested case-control studyDevelopment of preeclampsiaProspective birth cohort studyAssociated with increased riskPhthalate metabolite concentrationsCox proportional hazards modelsAdjusted Cox proportional hazards modelsCase-control studyAdjusted hazard ratiosCalculate hazard ratiosProportional hazards modelBirth cohort studyWeeks gestationPreterm birthAssociated with onsetPreeclampsiaUrinary BPA
2014
Longitudinal Profiling of Inflammatory Cytokines and C‐reactive Protein during Uncomplicated and Preterm Pregnancy
Ferguson K, McElrath T, Chen Y, Mukherjee B, Meeker J. Longitudinal Profiling of Inflammatory Cytokines and C‐reactive Protein during Uncomplicated and Preterm Pregnancy. American Journal Of Reproductive Immunology 2014, 72: 326-336. PMID: 24807462, PMCID: PMC4573571, DOI: 10.1111/aji.12265.Peer-Reviewed Original ResearchConceptsPreterm birthC-reactive proteinAssociated with increased oddsInflammation markersAssociated with increased odds of spontaneous preterm birthIL-10Associated with increased risk of preterm birthOdds of spontaneous preterm birthEtiology of preterm deliveryPredictors of preterm birthIL-6Risk of preterm birthPreterm premature ruptureSpontaneous preterm laborSpontaneous preterm birthIntrauterine growth restrictionNested case-control studyProfile of inflammatory cytokinesAssociated with increased riskCase-control studyPreterm laborPreterm pregnanciesPreterm deliveryGestational agePremature rupture
2011
Cumulative Exposure to Lead is associated with Increased Risk of Type-2 Diabetes: the VA Normative Aging Study (NAS)
Huang S, Park S, Mukherjee B, Nie H, Sparrow D, Hu H. Cumulative Exposure to Lead is associated with Increased Risk of Type-2 Diabetes: the VA Normative Aging Study (NAS). ISEE Conference Abstracts 2011, 2011 DOI: 10.1289/isee.2011.01547.Peer-Reviewed Original Research