2001
Plasma insulin, leptin, and soluble TNF receptors levels in relation to obesity-related atherogenic and thrombogenic cardiovascular disease risk factors among men
Chu N, Spiegelman D, Hotamisligil G, Rifai N, Stampfer M, Rimm E. Plasma insulin, leptin, and soluble TNF receptors levels in relation to obesity-related atherogenic and thrombogenic cardiovascular disease risk factors among men. Atherosclerosis 2001, 157: 495-503. PMID: 11472752, DOI: 10.1016/s0021-9150(00)00755-3.Peer-Reviewed Original ResearchConceptsCVD risk factorsRisk factorsPlasma insulinCVD riskHDL cholesterolInsulin levelsPlasma leptinAntigen levelsSoluble TNF receptor levelsCardiovascular disease risk factorsTissue plasminogen activator antigen levelsT-PA antigen levelsMetabolic cardiovascular syndromeHealth Professionals FollowIndependent risk factorDisease risk factorsEffect of obesitySoluble TNF receptorsTNF receptor levelsCardiovascular disease morbidityBody mass indexLevels of insulinProfessionals FollowLeptin levelsMass indexPlasma leptin concentrations and four-year weight gain among US men
Chu N, Spiegelman D, Yu J, Rifai N, Hotamisligil G, Rimm E. Plasma leptin concentrations and four-year weight gain among US men. International Journal Of Obesity 2001, 25: 346-353. PMID: 11319631, DOI: 10.1038/sj.ijo.0801549.Peer-Reviewed Original ResearchConceptsPlasma leptin concentrationsBaseline body mass indexPlasma leptin levelsLeptin levelsSubsequent weight gainLeptin concentrationsWeight gainInsulin levelsLeptin resistanceUS menSoluble tumor necrosis factor receptor levelsTumor necrosis factor receptor levelsBaseline plasma leptin levelsElevated plasma leptin concentrationsFour-year prospective studyDetailed lifestyle questionnaireHigher baseline leptinHealth Professionals FollowBody mass indexTotal energy intakeBody fat massPlasma insulin levelsDevelopment of obesityFollow-up questionnaireBaseline leptinDietary and lifestyle factors in relation to plasma leptin concentrations among normal weight and overweight men
Chu N, Stampfer M, Spiegelman D, Rifai N, Hotamisligil G, Rimm E. Dietary and lifestyle factors in relation to plasma leptin concentrations among normal weight and overweight men. International Journal Of Obesity 2001, 25: 106-114. PMID: 11244465, DOI: 10.1038/sj.ijo.0801468.Peer-Reviewed Original ResearchConceptsBody mass indexPlasma leptin concentrationsLow plasma leptin concentrationsBody fat massLeptin concentrationsPhysical activityNormal weightOverweight menFat intakeLifestyle factorsFat massBlood samplesConfounding variablesWeight gainMonounsaturated fat intakeY weight gainRecent prospective studiesVenous blood samplesCurrent smokingObese menCholesterol intakeObese subjectsMass indexPlasma leptinProspective study
2000
Glycemic status and soluble tumor necrosis factor receptor levels in relation to plasma leptin concentrations among normal weight and overweight US men
Chu N, Spiegelman D, Rifai N, Hotamisligil G, Rimm E. Glycemic status and soluble tumor necrosis factor receptor levels in relation to plasma leptin concentrations among normal weight and overweight US men. International Journal Of Obesity 2000, 24: 1085-1092. PMID: 11033975, DOI: 10.1038/sj.ijo.0801361.Peer-Reviewed Original ResearchConceptsPlasma leptinSTNF-R1C-peptideOverweight menGlycemic statusLeptin concentrationsGlucose homeostasisSoluble tumor necrosis factor receptor levelsSoluble tumour necrosis factor receptor concentrationsTumor necrosis factor receptor levelsDetailed lifestyle questionnaireSTNF-R2 concentrationsHealth Professionals FollowBody mass indexPlasma leptin levelsObesity-related disordersAdipose-derived cytokineCross-sectional studyConsiderable inter-individual variationProfessionals FollowDiabetes mellitusLeptin levelsMass indexNormal weightHighest quintile