2021
Analysis of Survival Among Adults With Early-Onset Colorectal Cancer in the National Cancer Database
Cheng E, Blackburn HN, Ng K, Spiegelman D, Irwin ML, Ma X, Gross CP, Tabung FK, Giovannucci EL, Kunz PL, Llor X, Billingsley K, Meyerhardt JA, Ahuja N, Fuchs CS. Analysis of Survival Among Adults With Early-Onset Colorectal Cancer in the National Cancer Database. JAMA Network Open 2021, 4: e2112539. PMID: 34132794, PMCID: PMC8209612, DOI: 10.1001/jamanetworkopen.2021.12539.Peer-Reviewed Original ResearchConceptsEarly-onset colorectal cancerOnset colorectal cancerNational Cancer DatabaseColorectal cancerAge 51Overall survivalCancer DatabaseIncidence of CRCCox proportional hazards regressionPrimary colorectal cancerKaplan-Meier analysisProportional hazards regressionAge 50 yearsAge 25 yearsAnalysis of survivalCohort studySurvival benefitHazards regressionUnadjusted analysesCancer incidenceMAIN OUTCOMEAge 35Survival advantageLower riskStage I
1998
Risk factors for adult T-cell leukemia among carriers of human T-lymphotropic virus type I.
Hisada M, Okayama A, Shioiri S, Spiegelman D, Stuver S, Mueller N. Risk factors for adult T-cell leukemia among carriers of human T-lymphotropic virus type I. Blood 1998, 92: 3557-61. PMID: 9808547, DOI: 10.1182/blood.v92.10.3557.422k09_3557_3561.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge of OnsetAgedAged, 80 and overBiomarkers, TumorCarrier StateCohort StudiesFemaleGene Products, taxHTLV-I AntibodiesHTLV-I InfectionsHuman T-lymphotropic virus 1HumansJapanLeukemia-Lymphoma, Adult T-CellMaleMiddle AgedNeoplastic Stem CellsProspective StudiesRisk FactorsSmokingT-LymphocytesConceptsAdult T-cell leukemiaHTLV-I carriersT-cell leukemiaAsymptomatic HTLV-I carriersHuman T-lymphotropic virus type IHuman T-lymphotropic virus type I.Miyazaki Cohort StudyHTLV-I antibodiesVirus type IAbnormal lymphocytesCohort studyViral markersATL diagnosisRisk factorsLow prevalenceFlower cellsATL casesGreater riskHTLVAntibodiesPositive controlType I.LeukemiaRegulatory proteinsType I