2020
The Association of Cooking Fuel Use, Dietary Intake, and Blood Pressure among Rural Women in China
Bellows AL, Spiegelman D, Du S, Jaacks LM. The Association of Cooking Fuel Use, Dietary Intake, and Blood Pressure among Rural Women in China. International Journal Of Environmental Research And Public Health 2020, 17: 5516. PMID: 32751678, PMCID: PMC7432946, DOI: 10.3390/ijerph17155516.Peer-Reviewed Original ResearchConceptsBlood pressureHigh blood pressureHousehold air pollutionDietary intakeDiastolic blood pressureSystolic blood pressureRole of dietYears of ageFatty acid-rich foodsNonpregnant womenSolid fuel useLinear mixed effects modelsSolid cooking fuelsAdverse effectsIntakeWomenMixed effects modelsPossible mediationLower ratesCooking fuel useEffects modelRural womenCooking fuelAssociationDiet
2004
Early life menstrual characteristics and pregnancy experiences among women with and without major depression: the Harvard study of moods and cycles
Harlow BL, Cohen LS, Otto MW, Spiegelman D, Cramer DW. Early life menstrual characteristics and pregnancy experiences among women with and without major depression: the Harvard study of moods and cycles. Journal Of Affective Disorders 2004, 79: 167-176. PMID: 15023491, DOI: 10.1016/s0165-0327(02)00459-7.Peer-Reviewed Original ResearchConceptsRisk of depressionMajor depressionHeavy menstrual flowMenstrual cycle characteristicsMonths of breastfeedingNumber of livebirthsYears of menstruationCurrent major depressionHistory of depressionMost risk estimatesPopulation-based sampleYears of ageWomen 36Menstrual characteristicsGynecological careStudy enrollmentDecreased riskMenstrual flowMenstrual cyclePostpartum periodCycle irregularityPsychiatric sequelaePregnancy experiencePremenstrual dysphoriaMultiple abortionsFactors influencing serum cystatin C levels other than renal function and the impact on renal function measurement
Knight EL, Verhave JC, Spiegelman D, Hillege HL, De Zeeuw D, Curhan GC, De Jong PE. Factors influencing serum cystatin C levels other than renal function and the impact on renal function measurement. Kidney International 2004, 65: 1416-1421. PMID: 15086483, DOI: 10.1111/j.1523-1755.2004.00517.x.Peer-Reviewed Original ResearchConceptsSerum cystatin C levelsCystatin C levelsSerum creatinine levelsSerum cystatin CRenal functionCreatinine levelsCreatinine clearanceCystatin CSerum creatininePartial Spearman correlationsC levelsCigarette smokingHigh serum C-reactive protein levelsHigher serum cystatin C levelsSerum C-reactive protein levelsC-reactive protein levelsSerum CRP levelsCurrent cigarette smokingRenal function measurementsSpearman correlationCross-sectional studyYears of ageCRP levelsMultivariate linear regression modelMale gender
2003
A Cross-Sectional Study of Alcohol Consumption Patterns and Biologic Markers of Glycemic Control Among 459 Women
Kroenke CH, Chu NF, Rifai N, Spiegelman D, Hankinson SE, Manson JE, Rimm EB. A Cross-Sectional Study of Alcohol Consumption Patterns and Biologic Markers of Glycemic Control Among 459 Women. Diabetes Care 2003, 26: 1971-1978. PMID: 12832298, DOI: 10.2337/diacare.26.7.1971.Peer-Reviewed Original ResearchConceptsHealth Study IIGlycemic controlAlcohol intakeBiologic markersNurses' Health Study IIBeneficial glycemic effectsAverage alcohol intakeModerate alcohol consumptionMain outcome measuresCross-sectional studyYears of ageAlcohol consumption patternsOverweight womenGlycemic effectsInsulin levelsLifestyle factorsInsulin resistanceDietary factorsInverse associationC-peptideAverage daily consumptionOutcome measuresPhysical activityBlood samplesAlcohol consumptionAlcohol Consumption Patterns and HbA1c, C-Peptide and Insulin Concentrations in Men
Meyer KA, Conigrave KM, Chu NF, Rifai N, Spiegelman D, Stampfer MJ, Rimm EB. Alcohol Consumption Patterns and HbA1c, C-Peptide and Insulin Concentrations in Men. Journal Of The American Nutrition Association 2003, 22: 185-194. PMID: 12805244, DOI: 10.1080/07315724.2003.10719292.Peer-Reviewed Original ResearchConceptsC-peptideInsulin concentrationsAverage alcohol consumptionAlcohol consumptionAlcohol consumption patternsBlood samplesStudy participantsDrinking patternsDisease-free menC-peptide concentrationsModerate alcohol consumptionCross-sectional studyYears of ageFrequent alcohol consumptionFrequency of consumptionEffects of alcoholInsulin levelsBiologic markersInsulin sensitivityInverse associationAverage daily consumptionIrregular drinkersObservational studyAnalysis of insulinHealth professionals
2002
Mercury and the Risk of Coronary Heart Disease in Men
Yoshizawa K, Rimm EB, Morris JS, Spate VL, Hsieh CC, Spiegelman D, Stampfer MJ, Willett WC. Mercury and the Risk of Coronary Heart Disease in Men. New England Journal Of Medicine 2002, 347: 1755-1760. PMID: 12456851, DOI: 10.1056/nejmoa021437.Peer-Reviewed Original ResearchConceptsCoronary heart diseaseHeart diseaseMale health professionalsHigh dietary intakeYears of ageCase-control designMercury levelsSmoking statusTotal mercury exposureControl subjectsLowest quintileRisk factorsDietary intakeCardiovascular diseaseRelative riskCohort membersPrevious historyToenail clippingsHealth professionalsDiseaseConsumption of fishMercury exposureMean mercury levelRiskFish consumption
2001
The effect of fruit and vegetable intake on risk for coronary heart disease.
Joshipura K, Hu F, Manson J, Stampfer M, Rimm E, Speizer F, Colditz G, Ascherio A, Rosner B, Spiegelman D, Willett W. The effect of fruit and vegetable intake on risk for coronary heart disease. Annals Of Internal Medicine 2001, 134: 1106-14. PMID: 11412050, DOI: 10.7326/0003-4819-134-12-200106190-00010.Peer-Reviewed Original ResearchConceptsCoronary heart diseaseHeart diseaseVegetable intakeGreen leafy vegetablesProtective effectHealth StudyVegetable consumptionFatal coronary heart diseaseStandard cardiovascular risk factorsVitamin CCardiovascular risk factorsNonfatal myocardial infarctionNurses' Health StudyProspective cohort studyFood frequency questionnaireIntake of fruitsRich fruitsMain outcome measuresApparent protective effectAssociation of fruitYears of ageConsumption of fruitsEffect of fruitConstituents of fruitsMen 40
2000
Prospective Study of Alcohol Consumption and the Risk of Age-Related Macular Degeneration
Cho E, Hankinson SE, Willett WC, Stampfer MJ, Spiegelman D, Speizer FE, Rimm EB, Seddon JM. Prospective Study of Alcohol Consumption and the Risk of Age-Related Macular Degeneration. JAMA Ophthalmology 2000, 118: 681-688. PMID: 10815161, DOI: 10.1001/archopht.118.5.681.Peer-Reviewed Original ResearchConceptsAge-related macular degenerationRisk of AMDProspective studyMacular degenerationAlcohol consumptionRelative riskDiagnosis of AMDSemiquantitative food frequency questionnaireMale health professionalsPooled relative riskFood frequency questionnaireModerate alcohol consumptionVisual acuity lossConfidence intervalsRisk of AgeRelationship of alcoholYears of ageAlcohol intakeAcuity lossRisk factorsPooled estimatesFemale nursesHealth professionalsAdditional subjectsWomenVitamin A supplementation and other predictors of anemia among children from Dar Es Salaam, Tanzania.
Villamor E, Mbise R, Spiegelman D, Ndossi G, Fawzi WW. Vitamin A supplementation and other predictors of anemia among children from Dar Es Salaam, Tanzania. American Journal Of Tropical Medicine And Hygiene 2000, 62: 590-7. PMID: 11289670, DOI: 10.4269/ajtmh.2000.62.590.Peer-Reviewed Original ResearchConceptsSevere anemiaHemoglobin levelsHuman immunodeficiency virus (HIV) infectionPredictors of anemiaPlacebo-controlled trialImmunodeficiency virus infectionMean hemoglobin levelAssociation of hemoglobinMonths of breastfeedingDiagnosis of malariaYears of agePotential confounding variablesMonth old infantsLow socioeconomic statusHIV infectionIndependent determinantsMalaria infectionMaternal levelsAdditional dosesNonsignificant reductionHematologic profileVirus infectionSignificant fallHemoglobin concentrationVitamin A
1999
Alcohol consumption in relation to breast cancer risk in a cohort of United States women 25-42 years of age.
Garland M, Hunter DJ, Colditz GA, Spiegelman DL, Manson JE, Stampfer MJ, Willett WC. Alcohol consumption in relation to breast cancer risk in a cohort of United States women 25-42 years of age. Cancer Epidemiology Biomarkers & Prevention 1999, 8: 1017-21. PMID: 10566558.Peer-Reviewed Original ResearchConceptsBreast cancer riskMultivariate relative riskAlcohol consumptionCancer riskRelative riskBreast cancerDrinks/weekInvasive breast cancerModerate alcohol consumptionMore drinks/weekAverage lifetime alcohol consumptionLifetime alcohol consumptionWomen age 25Past alcohol consumptionYears of agePostmenopausal womenPremenopausal womenWomen 25Age 25Young womenHeavy drinkingAge 23Drinking levelsWomenFurther studiesRecreational Physical Activity and the Risk of Cholecystectomy in Women
Leitzmann M, Rimm E, Willett W, Spiegelman D, Grodstein F, Stampfer M, Colditz G, Giovannucci E. Recreational Physical Activity and the Risk of Cholecystectomy in Women. New England Journal Of Medicine 1999, 341: 777-784. PMID: 10477775, DOI: 10.1056/nejm199909093411101.Peer-Reviewed Original ResearchConceptsRisk of cholecystectomyRecreational physical activityMultivariate relative riskPhysical activityGallstone diseaseRelative riskSedentary behaviorHealth StudyBody weightCases of cholecystectomyRecent weight lossNurses' Health StudyYears of ageSymptomatic cholelithiasisDecreased riskLowest quintileRisk factorsCholecystectomyWeight lossWeight changeWomenDiseaseActivity levelsWeeksRiskRisk Factors for Basal Cell Carcinoma of the Skin in Men: Results from the Health Professionals Follow-up Study
van Dam R, Huang Z, Rimm E, Weinstock M, Spiegelman D, Colditz G, Wiflett W, Giovannucci E. Risk Factors for Basal Cell Carcinoma of the Skin in Men: Results from the Health Professionals Follow-up Study. American Journal Of Epidemiology 1999, 150: 459-468. PMID: 10472945, DOI: 10.1093/oxfordjournals.aje.a010034.Peer-Reviewed Original ResearchConceptsBasal cell carcinomaBCC riskCell carcinomaSun exposureElevated riskUS male health professionalsMale health professionalsHealth Professionals FollowConstitutional factorsRisk of BCCYears of ageRegion of residenceBlistering sunburnsProfessionals FollowProspective cohortRisk factorsNorth European ancestryHealth professionalsLifetime numberCarcinomaRiskMenRed hairEuropean ancestrySkin
1998
A prospective study of physical activity and prostate cancer in male health professionals.
Giovannucci E, Leitzmann M, Spiegelman D, Rimm EB, Colditz GA, Stampfer MJ, Willett WC. A prospective study of physical activity and prostate cancer in male health professionals. Cancer Research 1998, 58: 5117-22. PMID: 9823321.Peer-Reviewed Original ResearchConceptsMale health professionalsTotal prostate cancerMetastatic prostate cancerProstate cancerPhysical activityMetabolic equivalentsVigorous activityLower riskHealth professionalsLeisure-time physical activityMore metabolic equivalentsNonvigorous physical activityReported average timeHealth Professionals FollowHistory of diabetesProspective cohort studyAdvanced prostate cancerRole of exerciseTime physical activityYears of ageWarrants further studyNonvigorous activitiesMen 40Professionals FollowCohort studyThe relation of physical activity to risk for symptomatic gallstone disease in men.
Leitzmann MF, Giovannucci EL, Rimm EB, Stampfer MJ, Spiegelman D, Wing AL, Willett WC. The relation of physical activity to risk for symptomatic gallstone disease in men. Annals Of Internal Medicine 1998, 128: 417-25. PMID: 9499324, DOI: 10.7326/0003-4819-128-6-199803150-00001.Peer-Reviewed Original ResearchConceptsSymptomatic gallstone diseaseGallstone diseasePhysical activityYears of ageSymptomatic gallstonesBody weightU.S. male health professionalsMale health professionalsProspective cohort studyUse of medicationsMen 65 yearsStrong inverse associationBiliary eventsMen 40Cohort studySmoking habitsExtreme quintilesAlcohol intakeRecent symptomsInverse associationMultiple confoundersMedical conditionsSedentary behaviorHigh riskHealth professionalsBody Anthropometry and the Risk of Hip and Wrist Fractures in Men: Results from a Prospective Study
Owusu W, Willett W, Ascherio A, Spiegelman D, Rimm E, Feskanich D, Colditz G. Body Anthropometry and the Risk of Hip and Wrist Fractures in Men: Results from a Prospective Study. Obesity 1998, 6: 12-19. PMID: 9526965, DOI: 10.1002/j.1550-8528.1998.tb00309.x.Peer-Reviewed Original ResearchConceptsWrist fracturesHip fractureRelative riskBody anthropometryHip ratioLowest quintileFracture casesNonsignificant inverse associationRisk of hipBody mass indexIncidence of hipIncidence of fracturesHip fracture casesYears of ageAvailable epidemiological informationModerate traumaWaist circumferenceMass indexFracture incidenceProspective studyHighest quintileInverse associationSignificant elevationAnthropometric indicatorsAdult men
1997
Comparison of dietary calcium with supplemental calcium and other nutrients as factors affecting the risk for kidney stones in women.
Curhan GC, Willett WC, Speizer FE, Spiegelman D, Stampfer MJ. Comparison of dietary calcium with supplemental calcium and other nutrients as factors affecting the risk for kidney stones in women. Annals Of Internal Medicine 1997, 126: 497-504. PMID: 9092314, DOI: 10.7326/0003-4819-126-7-199704010-00001.Peer-Reviewed Original ResearchConceptsHealth Study ISymptomatic kidney stonesDietary calciumSupplemental calciumRelative riskKidney stonesCalcium intakeHighest quintileLowest quintileRisk factorsSelf-administered food frequency questionnaireIncident symptomatic kidney stonesNurses' Health Study IStone formationAbsorption of oxalateFollowing relative risksDietary calcium intakeProspective cohort studyFood frequency questionnaireMain outcome measuresPotential risk factorsYears of ageCohort studyDecreased riskCalcium ingestionDietary Fiber, Glycemic Load, and Risk of NIDDM in Men
Salmerón J, Ascherio A, Rimm E, Colditz G, Spiegelman D, Jenkins D, Stampfer M, Wing A, Willett W. Dietary Fiber, Glycemic Load, and Risk of NIDDM in Men. Diabetes Care 1997, 20: 545-550. PMID: 9096978, DOI: 10.2337/diacare.20.4.545.Peer-Reviewed Original ResearchConceptsRisk of NIDDMHigh glycemic loadGlycemic loadCereal fiberRelative riskHigher cereal fiber intakeSemiquantitative food frequency questionnaireCereal fiber intakeLarge glycemic responseDietary glycemic indexFood frequency questionnaireIncidence of NIDDMIntake of carbohydratesTotal energy intakeLow glycemic loadYears of ageDietary fiberFrequency questionnaireIncident casesLowest quintileCardiovascular diseaseFamily historyFiber intakeNIDDMPhysical activity
1996
Birth weight and adult hypertension and obesity in women.
Curhan G, Chertow G, Willett W, Spiegelman D, Colditz G, Manson J, Speizer F, Stampfer M. Birth weight and adult hypertension and obesity in women. Circulation 1996, 94: 1310-5. PMID: 8822985, DOI: 10.1161/01.cir.94.6.1310.Peer-Reviewed Original ResearchConceptsAge-adjusted odds ratioHealth Study IIBody mass indexBirth weightYears of ageOdds ratioNHS IMass indexNurses' Health Study INurses' Health Study IIAdult body mass indexHealth Study INHS II cohortDevelopment of hypertensionLow birth weightPhysician-diagnosed hypertensionRisk of hypertensionHigh birth weightEarly life exposureAdult hypertensionNHS IIBlood pressureLowest quintileRisk factorsLife exposureVegetable, Fruit, and Cereal Fiber Intake and Risk of Coronary Heart Disease Among Men
Rimm EB, Ascherio A, Giovannucci E, Spiegelman D, Stampfer MJ, Willett WC. Vegetable, Fruit, and Cereal Fiber Intake and Risk of Coronary Heart Disease Among Men. JAMA 1996, 275: 447-451. PMID: 8627965, DOI: 10.1001/jama.1996.03530300031036.Peer-Reviewed Original ResearchConceptsTotal myocardial infarctionCoronary heart diseaseDietary fiber intakeMyocardial infarctionFiber intakeRelative riskCoronary diseaseHeart diseaseInverse associationCases of MIAge-adjusted relative riskTotal dietary fiber intakeDietary fiberCereal fiber intakeCardiovascular risk factorsNonfatal myocardial infarctionTotal energy intakeTotal fiber intakeCurrent national dietary guidelinesMain food contributorsFatal coronary diseaseYears of ageNational dietary guidelinesDietary questionnaireCohort studyProspective Study of Beverage Use and the Risk of Kidney Stones
Curhan G, Willett W, Rimm E, Spiegelman D, Stampfer M. Prospective Study of Beverage Use and the Risk of Kidney Stones. American Journal Of Epidemiology 1996, 143: 240-247. PMID: 8561157, DOI: 10.1093/oxfordjournals.aje.a008734.Peer-Reviewed Original ResearchConceptsFluid intakeKidney stonesStone formationProspective studySemiquantitative food frequency questionnaireBeverage useAdditional fluid intakeFood frequency questionnaireKidney stone riskSymptomatic kidney stonesTotal fluid intakeYears of ageThiazide useFrequency questionnaireStone recurrenceIncident casesType of beverageStone riskDietary intakeDecaffeinated coffeeDietary informationGrapefruit juiceIntakeSpecific beveragesBeverage type