2024
Demonstrating service delivery models for effective initiation and retention on pre-exposure prophylaxis (PrEP) among female bar workers in Dar es Salaam, Tanzania: A double randomized intervention study protocol
Chebet J, Akyoo W, Goymann H, Harling G, Barnhart D, Mosha I, Kamori D, Gandhi M, Mbunda T, Kipeleka J, Sando D, Spiegelman D, Mpembeni R, Bärnighausen T. Demonstrating service delivery models for effective initiation and retention on pre-exposure prophylaxis (PrEP) among female bar workers in Dar es Salaam, Tanzania: A double randomized intervention study protocol. PLOS ONE 2024, 19: e0304077. PMID: 38935796, PMCID: PMC11210872, DOI: 10.1371/journal.pone.0304077.Peer-Reviewed Original ResearchConceptsFemale bar workersPre-exposure prophylaxisIntention-to-treatBar workersPrimary outcomeRisk of HIV infectionAdherence to PrEPRisk of HIV acquisitionImprove PrEP adherenceGerman Clinical Trials RegisterPublic sector clinicsService delivery modelsRandomized trial designHIV negative womenPrevent HIV infectionHIV infectionPrEP provisionClinical Trials RegisterHIV testingPrEP initiationHealth facilitiesPromote PrEPPrEP adherenceDelivery modelsReduce barriers
2020
Getting to 90–90–90: Experiences from the MaxART Early Access to ART for All (EAAA) Trial in Eswatini
Walsh F, Khan S, Bärnighausen T, Hettema A, Lejeune C, Mazibuko S, Mlambo CK, Reis R, Fleming Y, Khumalo G, Zwane M, Okello V, Spiegelman D. Getting to 90–90–90: Experiences from the MaxART Early Access to ART for All (EAAA) Trial in Eswatini. Current HIV/AIDS Reports 2020, 17: 324-332. PMID: 32474844, DOI: 10.1007/s11904-020-00501-6.Peer-Reviewed Original ResearchConceptsTreatment guidelinesRoutine viral load monitoringNational HIV careViral load monitoringAdolescent malesSystem-level barriersEarly accessInnovative community-based approachesPublic health systemCommunity outreach strategiesImplementation science researchART initiationHIV careHIV testHIV testingMiddle-income countriesUNAIDS 90Adult menMultiple interventionsHealth systemAdolescent femalesEswatini MinistryTrialsFast trackBaseline dataIntegrating and Interpreting Findings from the Latest Treatment as Prevention Trials
Brault MA, Spiegelman D, Abdool Karim SS, Vermund SH. Integrating and Interpreting Findings from the Latest Treatment as Prevention Trials. Current HIV/AIDS Reports 2020, 17: 249-258. PMID: 32297219, PMCID: PMC7260110, DOI: 10.1007/s11904-020-00492-4.Peer-Reviewed Original Research
2017
A public health approach to addressing and preventing misdiagnosis in the scale‐up of HIV rapid testing programmes
Johnson C, Dalal S, Baggaley R, Taegtmeyer M, Johnson C, Dalal S, Baggaley R, Taegtmeyer M, Johnson C, Fonner V, Sands A, Ford N, Obermeyer C, Tsui S, Wong V, Baggaley R, Bock P, Phiri C, Piwowar‐Manning E, Kosloff B, Mandla N, Young A, James A, Schaap, Scheepers M, Donnell D, Griffith S, El‐Sadr W, Shanaube K, Beyers N, Hayes R, Fidler S, Ayles H, Team O, Khan S, Mafara E, Pasipamire M, Spiegelman D, Mazibuko S, Ntshalintshali N, Hettema A, Lejeune C, Walsh F, Okello V, Kufa T, Kharsany A, Cawood C, Khanyile D, Lewis L, Grobler A, Chipeta Z, Bere A, Glenshaw M, Puren A, Olaru I, McHugh G, Dakshina S, Majonga E, Dauya E, Bandason T, Kranzer K, Mujuru H, Ferrand R, Technau K, Mazanderani A, Kuhn L, Hans L, Strehlau R, Abrams E, Conradie M, Coovadia A, Mbete N, Murnane P, Patel F, Shiau S, Tiemessen C, Sherman G, Hsiao N, Zerbe A, Phillips T, Myer L, Abrams E, Sacks E, Cohn J, Penazzato M, Nguyen V, Best S, Pham H, Troung T, Hoang T, Wilson K, Ngo T, Chien X, Lai K, Bui D, Kato M. A public health approach to addressing and preventing misdiagnosis in the scale‐up of HIV rapid testing programmes. Journal Of The International AIDS Society 2017, 20: 22190. DOI: 10.7448/ias.20.7.22290.Peer-Reviewed Original ResearchFalse-negative diagnosesHIV testing servicesRapid diagnostic testsNegative diagnosisDiagnostic testsMagnitude of misdiagnosisHIV-negative individualsLife-long treatmentHIV testing practicesDiscrepant test resultsTesting servicesFalse-positive diagnosesHIV misdiagnosisAntiretroviral therapyUndiagnosed HIVHIV diagnosisHIV testingPositive diagnosisHIVTreatment targetsSystematic reviewPotential misdiagnosisDiagnosisMisdiagnosisSubstantial proportion
2000
Risk factors for HIV-1 seroprevalence among family planning clients in Dar es Salaam, Tanzania.
Kapiga SH, Lyamuya EF, Vuylsteke B, Spiegelman D, Larsen U, Hunter DJ. Risk factors for HIV-1 seroprevalence among family planning clients in Dar es Salaam, Tanzania. African Journal Of Reproductive Health 2000, 4: 88-99. PMID: 11000712, DOI: 10.2307/3583246.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge DistributionCross-Sectional StudiesFamily Planning ServicesFemaleHealth Knowledge, Attitudes, PracticeHIV SeroprevalenceHIV-1HumansMarital StatusOccupationsRisk FactorsSexually Transmitted DiseasesSocioeconomic FactorsSurveys and QuestionnairesTanzaniaUrban PopulationWomenConceptsRisk of HIVRisk factorsMajor public health problemHIV-1 seroprevalenceHIV risk factorsPrevalence of HIVCross-sectional studyPublic health problemDar es SalaamFamily planning servicesHIV infectionHIV testingFP clientsHIV interventionsHIVLaboratory evidenceHealth problemsLarge clinicsPlanning servicesWomenRiskMarried womenFurther spreadSeroprevalenceClinic