2012
Elevated alanine aminotransferase in antiretroviral‐naïve HIV‐infected African patients: magnitude and risk factors
Nagu T, Kanyangarara M, Hawkins C, Hertmark E, Chalamila G, Spiegelman D, Mugusi F, Fawzi W. Elevated alanine aminotransferase in antiretroviral‐naïve HIV‐infected African patients: magnitude and risk factors. HIV Medicine 2012, 13: 541-548. PMID: 22416813, PMCID: PMC3391335, DOI: 10.1111/j.1468-1293.2012.01006.x.Peer-Reviewed Original ResearchConceptsElevated alanine aminotransferaseIU/LAlanine aminotransferaseAntiretroviral therapyHigh riskWorld Health Organization clinical stageCD4 T-lymphocyte countFirst-line antiretroviral therapyHepatitis B virus coinfectionALT measurementsLow-density lipoprotein cholesterolLog-binomial regression modelsB virus coinfectionT-lymphocyte countsART-naïve HIVCells/μLHepatotoxic side effectsCurrent tuberculosis (TB) treatmentResource-limited settingsCross-sectional analysisAdvanced immunosuppressionHBV coinfectionART-naïveHIV careLipoprotein cholesterol
2000
Predictors of Change in the Functional Status of Children With Human Immunodeficiency Virus Infection
Missmer S, Spiegelman D, Gorbach S, Miller T. Predictors of Change in the Functional Status of Children With Human Immunodeficiency Virus Infection. Pediatrics 2000, 106: e24-e24. PMID: 10920180, DOI: 10.1542/peds.106.2.e24.Peer-Reviewed Original ResearchConceptsHeight z-scoreHuman immunodeficiency virus (HIV) infectionImmunodeficiency virus infectionTotal health scoreFunctional statusHealth scoresZ-scoreGeneral healthVirus infectionBaseline evaluationCD4 T-lymphocyte countFunctional status parametersFunctional status surveyHIV disease stageT-lymphocyte countsAbsolute CD4 countGeneral health scoresImportant clinical predictorsSignificant univariate predictorsFunctional status scoresMain outcome measuresNon-white raceResponsiveness scoresPredictors of changeCD4 count