2021
Diabetes Prevention Education Program in a population with pre-diabetes in Nepal: a study protocol of a cluster randomised controlled trial (DiPEP)
Shakya P, Shrestha A, Karmacharya BM, Shrestha A, Kulseng BE, Skovlund E, Sen A. Diabetes Prevention Education Program in a population with pre-diabetes in Nepal: a study protocol of a cluster randomised controlled trial (DiPEP). BMJ Open 2021, 11: e047067. PMID: 34819277, PMCID: PMC8614149, DOI: 10.1136/bmjopen-2020-047067.Peer-Reviewed Original ResearchConceptsDiabetes prevention education programIntervention armPrevention education programControl armRandom blood sugar valuesIndian Diabetes Risk ScoreNepal Health Research CouncilLifestyle intervention programDiabetes Risk ScoreBlood sugar valuesInstitutional Review CommitteeHealth Research CouncilKathmandu University SchoolWorkers/volunteersHealth Research EthicsDiabetes burdenStudy protocolHealthcare workersTwo-armHigh-income countriesOutcome measuresPhysical activityRisk scoreHealth literacyQualitative studyFactors associated with low back pain among construction workers in Nepal: A cross-sectional study
Adhikari B, Ghimire A, Jha N, Karkee R, Shrestha A, Dhakal R, Niraula A, Majhi S, Pandit AK, Bhandari N. Factors associated with low back pain among construction workers in Nepal: A cross-sectional study. PLOS ONE 2021, 16: e0252564. PMID: 34061897, PMCID: PMC8168885, DOI: 10.1371/journal.pone.0252564.Peer-Reviewed Original ResearchConceptsLow back painCross-sectional studyBack painFactors of LBPCommunity-based cross-sectional studyPrevalence of LBPOne-year prevalenceConfidence intervalsHealthcare servicesPublic health professionalsConstruction workersEligible participantsCommon causeHigher oddsSleep qualityHealth promotionHealth professionalsSemi-structured questionnaireLogistic regressionPrevalencePainFace interviewsR programming softwareKavre districtPreventive techniques
2020
Proactive prevention: Act now to disrupt the impending non-communicable disease crisis in low-burden populations
Njuguna B, Fletcher SL, Akwanalo C, Asante KP, Baumann A, Brown A, Davila-Roman VG, Dickhaus J, Fort M, Iwelunmor J, Irazola V, Mohan S, Mutabazi V, Newsome B, Ogedegbe O, Pastakia SD, Peprah EK, Plange-Rhule J, Roth G, Shrestha A, Watkins DA, Vedanthan R. Proactive prevention: Act now to disrupt the impending non-communicable disease crisis in low-burden populations. PLOS ONE 2020, 15: e0243004. PMID: 33259517, PMCID: PMC7707577, DOI: 10.1371/journal.pone.0243004.Peer-Reviewed Original ResearchMeSH KeywordsCost of IllnessHealth PrioritiesHumansNoncommunicable DiseasesPolicy MakingRisk FactorsConceptsPrevention effortsLow-risk populationHigh-burden populationsDisease prevention effortsLow-prevalence populationsPublic health expertsNon-communicable disease crisisLow feasibilityNCD crisisPrevention strategiesEpidemiological transitionPotential interventionsYoung individualsHealth expertsInterventionProactive prevention strategiesDisease crisisPopulationProactive preventionHigh feasibilityNUrse-led COntinuum of care for people with Diabetes and prediabetes (NUCOD) in Nepal: study protocol for a cluster randomized controlled trial
Xu D, Dev R, Shrestha A, Zhang L, Shrestha A, Shakya P, Hughes JP, Shakya PR, Li J, Liao J, Karmacharya BM. NUrse-led COntinuum of care for people with Diabetes and prediabetes (NUCOD) in Nepal: study protocol for a cluster randomized controlled trial. Trials 2020, 21: 442. PMID: 32471476, PMCID: PMC7257188, DOI: 10.1186/s13063-020-04372-5.Peer-Reviewed Original ResearchMeSH KeywordsCluster AnalysisContinuity of Patient CareCost-Benefit AnalysisDiabetes Mellitus, Type 2Glycated HemoglobinHumansMulticenter Studies as TopicNepalNurse's RoleNursing ServicesOutcome and Process Assessment, Health CarePatient Education as TopicPrediabetic StateProgram EvaluationRandomized Controlled Trials as TopicRisk FactorsRisk Reduction BehaviorConceptsUsual treatment groupPrimary care centersType 2 diabetesManagement of diabetesRE-AIM frameworkImplementation outcomesContinuum of careUnit of randomizationLow-income settingsPrediabetes individualsTreat basisDiabetes nursesDiabetes preventionPrimary outcomeClinical outcomesHemoglobin levelsDiabetes individualsDiabetes programParallel groupStudy protocolCare centerIntervention groupTwo-armCare modelCare approach
2019
Prevalence and associated factors of childhood overweight/obesity among primary school children in urban Nepal
Karki A, Shrestha A, Subedi N. Prevalence and associated factors of childhood overweight/obesity among primary school children in urban Nepal. BMC Public Health 2019, 19: 1055. PMID: 31387571, PMCID: PMC6685156, DOI: 10.1186/s12889-019-7406-9.Peer-Reviewed Original ResearchConceptsChildhood overweight/obesityOverweight/obesityOverweight/obeseChildren of mothersTwo-stage cluster random samplingMale childrenMultivariate logistic regression analysisPrimary school childrenMajor public health concernMethodsA cross-sectional surveyLogistic regression analysisAdverse health consequencesUrban primary school childrenEnergy-dense foodsPublic health concernStructured self-administered questionnaireCross-sectional surveyJunk food consumptionChi-square testSchool childrenSPSS version 21Self-administered questionnaireChildhood overweightParents of childrenAssociated FactorsCardio-metabolic disease risk factors among South Asian labour migrants to the Middle East: a scoping review and policy analysis
Mishra SR, Ghimire S, Joshi C, Gyawali B, Shrestha A, Neupane D, Sharma SR, Pokharel Y, Virani SS. Cardio-metabolic disease risk factors among South Asian labour migrants to the Middle East: a scoping review and policy analysis. Globalization And Health 2019, 15: 33. PMID: 31046779, PMCID: PMC6498694, DOI: 10.1186/s12992-019-0468-8.Peer-Reviewed Original ResearchConceptsDisease risk factorsBetter cardiometabolic healthRisk factorsDiabetes mellitusHigh burdenCardio-metabolic disease risk factorsMetabolic disease risk factorsCardio-metabolic risk factorsRisk factor burdenMore risk factorsPubMed/MEDLINEGrey literature searchCardiometabolic healthChronic diseasesSouth Asian migrantsMigrant healthSimilar burdenOverweightLiterature searchObesityQualitative synthesisHypertensionScreening targetsBurdenDiabetesNepal Pioneer Worksite Intervention Study to lower cardio-metabolic risk factors: design and protocol
Shrestha A, Tamrakar D, Karmacharya BM, Shrestha A, Shrestha R, Bhatta RD, Pyakurel P, Khudyakov P, Malik V, Mattei J, Spiegelman D. Nepal Pioneer Worksite Intervention Study to lower cardio-metabolic risk factors: design and protocol. BMC Cardiovascular Disorders 2019, 19: 48. PMID: 30819098, PMCID: PMC6393979, DOI: 10.1186/s12872-019-1025-3.Peer-Reviewed Original ResearchMeSH KeywordsCardiovascular DiseasesDiet, HealthyExerciseFemaleFood ServicesHealth Knowledge, Attitudes, PracticeHumansMaleMetabolic SyndromeNepalOccupational Health ServicesPatient Education as TopicProtective FactorsRandomized Controlled Trials as TopicRisk FactorsRisk Reduction BehaviorTime FactorsTreatment OutcomeConceptsCardio-metabolic riskWorksite intervention studiesIntervention studiesBlood sugarCardiovascular disease prevention effortsPrevention programsCardio-metabolic risk factorsBehavioral interventionsCardio-metabolic outcomesTrial registrationThe trialElevated blood pressureDiabetes Prevention ProgramCardiovascular disease burdenProportion of participantsDisease prevention effortsHealthy food choicesChi-square testEnvironmental-level changesIndividual behavioral interventionsDhulikhel HospitalBlood pressureDietary interventionPre-post designLifestyle factorsDisease burdenSocio-economic inequalities in hypertension burden and cascade of services: nationwide cross-sectional study in Nepal
Mishra SR, Ghimire S, Shrestha N, Shrestha A, Virani SS. Socio-economic inequalities in hypertension burden and cascade of services: nationwide cross-sectional study in Nepal. Journal Of Human Hypertension 2019, 33: 613-625. PMID: 30659279, DOI: 10.1038/s41371-019-0165-3.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedBlood PressureCross-Sectional StudiesEducational StatusFemaleHealth Knowledge, Attitudes, PracticeHealth Services AccessibilityHealth Status DisparitiesHealthcare DisparitiesHumansHypertensionIncomeMaleMiddle AgedNepalPrevalenceResidence CharacteristicsRisk AssessmentRisk FactorsSocial Determinants of HealthYoung AdultConceptsCascade of servicesNationwide cross-sectional studyPrevalence of hypertensionControl of hypertensionBody mass indexMulti-variable logistic regressionTreatment of hypertensionCross-sectional studyNepal Demographic Health SurveyLowest wealth quintileSocio-economic inequalitiesDemographic Health SurveyHousehold wealth statusHypertension burdenTotal hypertensivesHypertensive femalesHypertension awarenessHypertension prevalenceBlood pressureMass indexHypertension statusDisease burdenHealth SurveyHypertensionCoverage of services
2018
Quit Intentions and Attempts among Smokers in Sub-urban Nepal: Findings from the Dhulikhel Heart Study.
Karmacharya BM, Fitzpatrick AL, Koju R, Sotodehnia N, Xu DR, Pradhan PMS, Shrestha A. Quit Intentions and Attempts among Smokers in Sub-urban Nepal: Findings from the Dhulikhel Heart Study. Kathmandu University Medical Journal 2018, 16: 83-88. PMID: 30631024.Peer-Reviewed Original ResearchConceptsDhulikhel Heart StudyQuit attemptsCurrent smokersSmoking cessationCessation programsHeart StudyEffective smoking cessation interventionsCVD risk factorsSmoking cessation interventionSmoking cessation programTobacco cessation programCross-sectional studyNon-communicable diseasesHigh alcohol consumptionPast quit attemptsEvidence-based strategiesSocio-demographic factorsNational Health SystemFormer smokersTobacco cessationSuccessful quittingRisk factorsQuit effortsTobacco useTobacco consumption
2017
Awareness, Prevalence, Treatment, and Control of Hypertension in Western Nepal
Neupane D, Shrestha A, Mishra SR, Bloch J, Christensen B, McLachlan CS, Karki A, Kallestrup P. Awareness, Prevalence, Treatment, and Control of Hypertension in Western Nepal. American Journal Of Hypertension 2017, 30: 907-913. PMID: 28531244, DOI: 10.1093/ajh/hpx074.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntihypertensive AgentsAwarenessBlood PressureChi-Square DistributionCross-Sectional StudiesFemaleHealth Care SurveysHealth Knowledge, Attitudes, PracticeHumansHypertensionLife StyleLogistic ModelsMaleMiddle AgedMultivariate AnalysisNepalOdds RatioPrevalenceRisk FactorsRisk Reduction BehaviorSuburban HealthTreatment OutcomeConceptsControl of hypertensionBlood pressureRisk factorsHigher body mass indexBP control targetsPrevalence of hypertensionModifiable risk factorsSex-adjusted prevalenceDiastolic blood pressureLow physical activitySystolic blood pressureBody mass indexHarmful alcohol intakeHarmful alcohol drinkersCross-sectional surveyLow-income settingsSemi-urban settingHypertension burdenHypertensive medicationsPreexisting hypertensionHypertensive participantsAntihypertensive medicinesRenal diseaseMass indexAlcohol drinkersPrevalence and Correlates of Tobacco Use in a Suburban community of Nepal: Findings from the Dhulikhel Heart Study.
Karmacharya B, Shrestha A, Fitzpatrick AL, Koju R, Sotodehnia N, Xu DR. Prevalence and Correlates of Tobacco Use in a Suburban community of Nepal: Findings from the Dhulikhel Heart Study. Kathmandu University Medical Journal 2017, 15: 336-342. PMID: 30580353.Peer-Reviewed Original ResearchConceptsDhulikhel Heart StudyOral tobacco useOral tobaccoTobacco useBrahmin/ChhetriCurrent smokersRisk factorsHeart StudyTobacco consumptionAdults age 18 yearsCVD risk factorsPrevalence of smokingBody mass indexImportant risk factorAge 18 yearsOdds of smokingSuburban populationBackground SmokingMass indexSectional studyChronic diseasesEpidemiological aspectsModerate drinkersAlcohol consumptionHigh drinkers