Cancer Studies
Understanding colon cancer heterogeneity by metabolomics
We will investigate the metabolic differences in tumors that form in different regions of the colon and identify those that have tumorigenic actions.
Principal Investigator:
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Caroline Johnson, PhD, Associate Professor, Department of Environmental Health Sciences; email: caroline.johnson@yale.edu
Tumor Microenvironment
Tumor microenvironment metabolite composition regulates anti-melanoma immune responses
We will identify how metabolites regulate immune cells in a novel melanoma mouse model.
Principal Investigator:
- Caroline Johnson, PhD, Associate Professor, Department of Environmental Health Sciences; email: caroline.johnson@yale.edu
Molecular Cancer Microbiology
Molecular cancer microbiology and the underpinnings of microbiome-associated carcinogenesis
We will identify novel links between colorectal cancer microbiome and disease trajectory.
Co-Principal Investigator:
- Caroline Johnson, PhD, Associate Professor, Department of Environmental Health Sciences; email: caroline.johnson@yale.edu