Exposome-Wide Ranking to Uncover Environmental Chemicals Associated with Dyslipidemia: A Panel Study in Healthy Older Chinese Adults from the BAPE Study.
Ding E, Deng F, Fang J, Liu J, Yan W, Yao Q, Miao K, Wang Y, Sun P, Li C, Liu Y, Dong H, Dong L, Zhang X, Lu Y, Lin X, Ding C, Li T, Shi Y, Cai Y, Liu X, Godri Pollitt K, Ji J, Tong S, Tang S, Shi X. Exposome-Wide Ranking to Uncover Environmental Chemicals Associated with Dyslipidemia: A Panel Study in Healthy Older Chinese Adults from the BAPE Study. Environmental Health Perspectives 2024, 132: 97005. PMID: 39240788, PMCID: PMC11379127, DOI: 10.1289/ehp13864.Peer-Reviewed Original ResearchMeSH KeywordsAgedBiomarkersChinaDyslipidemiasEast Asian PeopleEnvironmental ExposureEnvironmental PollutantsExposomeFemaleHumansLongitudinal StudiesMaleMiddle AgedConceptsDyslipidemia markersCardiovascular diseaseMulti-omicsMarkers of dyslipidemiaExamination of cytokinesMeasurement of cytokinesSerum lipidomeSystemic inflammationMulti-omics profilingCardiac functionDyslipidemiaPrimary preventionClinical measuresSerumChinese adultsBlood transcriptomeImpact spectraCytokinesExposome-wide association studyInflammationMarkersBiomolecular pathwaysAssociationHealthy older adultsElectrocardiogramAssociations between serum per- and polyfluoroalkyl substances and thyroid hormones in Chinese adults: A nationally representative cross-sectional study
Xing Y, Li Z, Wang J, Qu Y, Hu Q, Ji S, Chang X, Zhao F, Lv Y, Pan Y, Shi X, Dai J. Associations between serum per- and polyfluoroalkyl substances and thyroid hormones in Chinese adults: A nationally representative cross-sectional study. Environment International 2024, 184: 108459. PMID: 38320373, DOI: 10.1016/j.envint.2024.108459.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlkanesulfonic AcidsBayes TheoremChinaCross-Sectional StudiesEnvironmental PollutantsFatty AcidsFemaleFluorocarbonsHumansMaleThyroid HormonesConceptsRestricted cubic splinesBayesian kernel machine regressionNationally representative cross-sectional studyNonlinear dose-response associationDose-response associationChinese adult populationWeighted multiple linear regressionGeneral Chinese populationCross-sectional studyNationally representative dataYounger age groupsKernel machine regressionChinese adultsInverse associationG-computationPerfluoroheptane sulfonic acidQuantile-based g-computationAdult populationRepresentative dataSignificant associationPositive associationThyroid homeostasisChinese populationMultiple linear regressionAge groups