Determination of persistent organochlorine pollutants in human serum by combining liquid-liquid extraction and solid-phase extraction with gas chromatography-tandem mass spectrometry
Qiu T, Jiang W, Bao S, Qian J, Wang C, Tang S, Shi X, Lu Y. Determination of persistent organochlorine pollutants in human serum by combining liquid-liquid extraction and solid-phase extraction with gas chromatography-tandem mass spectrometry. Microchemical Journal 2024, 197: 109699. DOI: 10.1016/j.microc.2023.109699.Peer-Reviewed Original ResearchSolid-phase extractionGas chromatography-tandem mass spectrometryLiquid-liquid extractionPersistent organochlorine pollutantsChromatography-tandem mass spectrometryMatrix effectsTarget analytesMass spectrometryMultiple reaction monitoring (MRM) modeReaction monitoring modeMethod detection limitsOrganochlorine pollutantsElectron impactSample preparation procedureGC-MS/MSDifferent spike levelsHuman serumApplicable analytical methodsLimit of quantificationMethyl tert-butyl etherQuality control samplesMonitoring modeTert-butyl etherDetection limitPreparation procedure