2023
Season of Conception and Risk of Cerebral Palsy
Zhuo H, Ritz B, Warren J, Liew Z. Season of Conception and Risk of Cerebral Palsy. JAMA Network Open 2023, 6: e2335164. PMID: 37738049, PMCID: PMC10517373, DOI: 10.1001/jamanetworkopen.2023.35164.Peer-Reviewed Original ResearchConceptsCerebral palsySeason of conceptionCalifornia birth recordsCohort studyPreterm birthRelative riskBirth recordsRisk of CPStatewide cohort studyEtiological risk factorsHigher Social Vulnerability IndexLength of gestationDiagnostic recordsNeighborhood-level factorsSummer conceptionsRisk factorsStratified analysisLive birthsMAIN OUTCOMEHigh riskCP riskPoisson regressionCP statusDevelopmental servicesNeuromotor disabilitiesExposure to per- and polyfluoroalkyl substances in early pregnancy and risk of cerebral palsy in children
Vilhelmsson A, Rylander L, Jöud A, Lindh C, Mattsson K, Liew Z, Guo P, Ritz B, Källén K, Thacher J. Exposure to per- and polyfluoroalkyl substances in early pregnancy and risk of cerebral palsy in children. The Science Of The Total Environment 2023, 899: 165622. PMID: 37474063, DOI: 10.1016/j.scitotenv.2023.165622.Peer-Reviewed Original ResearchConceptsOdds ratioPreterm infantsEarly pregnancyPerfluorononanoic acidPrenatal PFAS exposureMaternal serum concentrationsCerebral palsy casesConfidence intervalsCase-control studyRisk of CPEnvironmental risk factorsPositive associationContinuous variablesHigh PFASPalsy casesBirth RegistryPreterm controlsCerebral palsyLifestyle factorsPreterm casesUnexplained etiologyPrenatal exposureSerum concentrationsRisk factorsPerfluorooctane sulfonate
2022
Parental Age and Childhood Risk for Cerebral Palsy in California
Zhou L, Meng Q, von Ehrenstein O, Xiao J, Gao Y, Wu Y, Ritz B, Liew Z. Parental Age and Childhood Risk for Cerebral Palsy in California. The Journal Of Pediatrics 2022, 255: 147-153.e6. PMID: 36372095, PMCID: PMC10121738, DOI: 10.1016/j.jpeds.2022.10.039.Peer-Reviewed Original ResearchConceptsCerebral palsyPaternal ageGreater riskPreterm birthMaternal ageParental ageRisk of CPYoung maternal ageBirth certificate recordsCase-control studyTime of deliveryChildren of mothersOlder paternal ageCP diagnosisPreterm deliveryOffspring riskCertificate recordsCP casesCP riskSingleton controlsAge 20Older mothersAge 25Older ageChildhood risk
2014
Prenatal Exposure to Perfluoroalkyl Substances and the Risk of Congenital Cerebral Palsy in Children
Liew Z, Ritz B, Bonefeld-Jørgensen EC, Henriksen TB, Nohr EA, Bech BH, Fei C, Bossi R, von Ehrenstein OS, Streja E, Uldall P, Olsen J. Prenatal Exposure to Perfluoroalkyl Substances and the Risk of Congenital Cerebral Palsy in Children. American Journal Of Epidemiology 2014, 180: 574-581. PMID: 25139206, DOI: 10.1093/aje/kwu179.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlkanesulfonic AcidsCaprylatesCase-Control StudiesCerebral PalsyCohort StudiesDenmarkEndocrine DisruptorsEnvironmental MonitoringEnvironmental PollutantsFemaleFluorocarbonsHumansInfant, NewbornMaleMaternal AgeOdds RatioPregnancyPrenatal Exposure Delayed EffectsSex DistributionSex FactorsYoung AdultConceptsCongenital cerebral palsyPrenatal exposureCerebral palsyDanish National Birth CohortCerebral Palsy RegisterNational Birth CohortFetal brain developmentDose-response patternCase-cohort designPerfluoroalkyl substancesLiveborn singletonsMaternal levelsRisk ratioHigh riskCP casesCP riskBirth cohortMaternal plasmaBrain developmentPalsyPerfluorooctane sulfonateRiskPFAS levelsCohortPerfluorooctanoic acid