2010
Preterm birth results in alterations in neural connectivity at age 16 years
Mullen KM, Vohr BR, Katz KH, Schneider KC, Lacadie C, Hampson M, Makuch RW, Reiss AL, Constable RT, Ment LR. Preterm birth results in alterations in neural connectivity at age 16 years. NeuroImage 2010, 54: 2563-2570. PMID: 21073965, PMCID: PMC3020252, DOI: 10.1016/j.neuroimage.2010.11.019.Peer-Reviewed Original ResearchConceptsDiffusion tensor imagingAge 16 yearsPT subjectsBrain injuryLow birth weight preterm childrenTerm controlsUncinate fasciculusBilateral external capsuleFA valuesWeight preterm childrenNeonatal brain injuryLower fractional anisotropy valuesYears of ageBilateral uncinate fasciculusFractional anisotropy valuesRight uncinate fasciculusRight arcuate fasciculusWhite matter disorganizationAlternative neural pathwaysPreterm birthExternal capsuleInferior frontal gyrusPreterm childrenCorpus callosumHigh riskFunctional connectivity to a right hemisphere language center in prematurely born adolescents
Myers EH, Hampson M, Vohr B, Lacadie C, Frost SJ, Pugh KR, Katz KH, Schneider KC, Makuch RW, Constable RT, Ment LR. Functional connectivity to a right hemisphere language center in prematurely born adolescents. NeuroImage 2010, 51: 1445-1452. PMID: 20347043, PMCID: PMC2872040, DOI: 10.1016/j.neuroimage.2010.03.049.Peer-Reviewed Original ResearchConceptsFunctional connectivityWord Reading EfficiencyVerbal Comprehension IndexWechsler Intelligence ScaleRight supramarginal gyrusPeabody Picture VocabularyGreater cognitive deficitsPPVT-R scoresPhonological processingComprehension IndexLanguage tasksChildren-IIIIntelligence ScaleReading efficiencyLanguage deficitsPicture VocabularyWISC-IIISupramarginal gyrusCognitive outcomesNeurobiological basisHemisphere regionsCognitive deficitsWernicke's areaNeural activityLanguage processing
2009
Alterations in neural connectivity in preterm children at school age
Gozzo Y, Vohr B, Lacadie C, Hampson M, Katz KH, Maller-Kesselman J, Schneider KC, Peterson BS, Rajeevan N, Makuch RW, Constable RT, Ment LR. Alterations in neural connectivity in preterm children at school age. NeuroImage 2009, 48: 458-463. PMID: 19560547, PMCID: PMC2775072, DOI: 10.1016/j.neuroimage.2009.06.046.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingLanguage tasksWernicke's areaLanguage processingPeabody Individual Achievement TestRight inferior frontal gyrusPT childrenAuditory language functionsAuditory language taskCortical language regionsSchool ageInferior frontal gyrusReading comprehension testWechsler Intelligence ScalePeabody Picture VocabularyInferior parietal lobulePT subjectsSchool-aged childrenChildren-IIIComprehension testFrontal gyrusIntelligence ScalePicture VocabularyWISC-IIILanguage regions
2000
Regional Brain Volume Abnormalities and Long-term Cognitive Outcome in Preterm Infants
Peterson B, Vohr B, Staib L, Cannistraci C, Dolberg A, Schneider K, Katz K, Westerveld M, Sparrow S, Anderson A, Duncan C, Makuch R, Gore J, Ment L. Regional Brain Volume Abnormalities and Long-term Cognitive Outcome in Preterm Infants. JAMA 2000, 284: 1939-1947. PMID: 11035890, DOI: 10.1001/jama.284.15.1939.Peer-Reviewed Original ResearchConceptsRegional brain volumesLong-term cognitive outcomesPreterm childrenPreterm infantsBrain volumeBasal gangliaCorpus callosumCognitive outcomesRegional brain volume abnormalitiesTerm control childrenCase-control studyBrain volume abnormalitiesPoor cognitive outcomesRegional cortical volumesStructural magnetic resonanceMidtemporal cortexPreterm birthPremature birthTemporal hornPerinatal variablesSubgenual cortexUniversity Medical SchoolCortical volumeHigh prevalenceLongitudinal followOutcome of Children in the Indomethacin Intraventricular Hemorrhage Prevention Trial
Ment L, Vohr B, Allan W, Westerveld M, Sparrow S, Schneider K, Katz K, Duncan C, Makuch R. Outcome of Children in the Indomethacin Intraventricular Hemorrhage Prevention Trial. Pediatrics 2000, 105: 485-491. PMID: 10699097, DOI: 10.1542/peds.105.3.485.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Inflammatory Agents, Non-SteroidalBrain Damage, ChronicCerebral HemorrhageCerebral VentriclesChild, PreschoolDose-Response Relationship, DrugFemaleFollow-Up StudiesHumansIndomethacinInfantInfant, NewbornInfant, Premature, DiseasesMaleNeurologic ExaminationNeuropsychological TestsPregnancyConceptsLow-dose indomethacinIntraventricular hemorrhagePlacebo childrenIndomethacin therapyPreterm infantsEarly administrationNeurologic examinationPrevention trialsLow birth weight preterm infantsStudy childrenBirth weight preterm infantsSeverity of IVHLow birth weight survivorsMean gestational ageWeight preterm infantsAdverse neurodevelopmental outcomesOutcome of childrenStandard neurologic examinationYears of ageNeurodevelopmental handicapPreterm neonatesNeurodevelopmental examinationNeurodevelopmental outcomesCerebral palsyGestational age
1999
The Etiology and Outcome of Cerebral Ventriculomegaly at Term in Very Low Birth Weight Preterm Infants
Ment L, Vohr B, Allan W, Westerveld M, Katz K, Schneider K, Makuch R. The Etiology and Outcome of Cerebral Ventriculomegaly at Term in Very Low Birth Weight Preterm Infants. Pediatrics 1999, 104: 243-248. PMID: 10429002, DOI: 10.1542/peds.104.2.243.Peer-Reviewed Original ResearchConceptsBronchopulmonary dysplasiaPreterm infantsCorrected ageIndependent predictorsCerebral ventriculomegalyBirth weightGrade 3Low birth weight preterm infantsBirth weight preterm infantsMaternal educationLow birth weight survivorsCause of ventriculomegalyDevelopment of ventriculomegalyGrades of IVHIncidence of handicapWeight preterm infantsMonths' corrected ageAdverse neurodevelopmental outcomesLow birth weightYears' corrected ageAdverse cognitive outcomesLogistic regression analysisYears of ageApgar scoreNeurodevelopmental handicapEarly-onset intraventricular hemorrhage in preterm neonates: Incidence of neurodevelopmental handicap
Vohr B, Allan W, Scott D, Katz K, Schneider K, Makuch R, Ment L. Early-onset intraventricular hemorrhage in preterm neonates: Incidence of neurodevelopmental handicap. Seminars In Perinatology 1999, 23: 212-217. PMID: 10405190, DOI: 10.1016/s0146-0005(99)80065-2.Peer-Reviewed Original ResearchConceptsIntraventricular hemorrhageEarly intraventricular hemorrhageLow birth weight infantsBirth weight infantsHours of lifeYears of agePostnatal indomethacinNeurodevelopmental handicapWeight infantsPreterm infantsPreterm neonatesNeurodevelopmental outcomesNeurological examinationCerebral palsyPostnatal hoursStudy infantsHigh riskMotor handicapIntelligence quotient scoresInfantsEarly onsetHemorrhageAgeQuotient scoresChildren
1998
Cognitive Outcome at 4½ Years of Very Low Birth Weight Infants Enrolled in the Multicenter Indomethacin Intraventricular Hemorrhage Prevention Trial
Ment L, Westerveld M, Makuch R, Vohr B, Allan W. Cognitive Outcome at 4½ Years of Very Low Birth Weight Infants Enrolled in the Multicenter Indomethacin Intraventricular Hemorrhage Prevention Trial. Pediatrics 1998, 102: 159-159. PMID: 9714645, DOI: 10.1542/peds.102.1.159.Peer-Reviewed Original Research
1997
Antecedents of Cerebral Palsy in a Multicenter Trial of Indomethacin for Intraventricular Hemorrhage
Allan W, Vohr B, Makuch R, Katz K, Ment L. Antecedents of Cerebral Palsy in a Multicenter Trial of Indomethacin for Intraventricular Hemorrhage. JAMA Pediatrics 1997, 151: 580-585. PMID: 9193243, DOI: 10.1001/archpedi.1997.02170430046010.Peer-Reviewed Original ResearchConceptsCranial US findingsIntraventricular hemorrhageUS findingsWeight infantsBronchopulmonary dysplasiaPeriventricular leukomalaciaCerebral palsyNeonatal intensive care unitCerebral palsy ratesActive treatment groupIntensive care unitSurfactant replacement therapyIncidence of CPPalsy rateHospital daysPreterm infantsCohort followIndependent predictorsMulticenter trialNeurologic examinationCare unitReplacement therapyUltrasonographic scansBirth weightCranial US
1996
Neurodevelopmental outcome at 36 months' corrected age of preterm infants in the Multicenter Indomethacin Intraventricular Hemorrhage Prevention Trial.
Ment L, Vohr B, Oh W, Scott D, Allan W, Westerveld M, Duncan C, Ehrenkranz R, Katz K, Schneider K, Makuch R. Neurodevelopmental outcome at 36 months' corrected age of preterm infants in the Multicenter Indomethacin Intraventricular Hemorrhage Prevention Trial. Pediatrics 1996, 98: 714-8. PMID: 8885951, DOI: 10.1542/peds.98.4.714.Peer-Reviewed Original ResearchMeSH KeywordsCerebral HemorrhageChild DevelopmentChild, PreschoolChi-Square DistributionCyclooxygenase InhibitorsHumansIndomethacinInfantInfant, NewbornInfant, PrematureInfant, Premature, DiseasesInfant, Very Low Birth WeightIntelligence TestsNeurologic ExaminationUltrasonography, Doppler, TranscranialConceptsLow-dose indomethacinMonths' corrected ageIntraventricular hemorrhageCorrected ageNeurodevelopmental followLong-term neurodevelopmental followLow birth weight infantsLow birth weight neonatesBirth weight infantsMean gestational ageBirth weight neonatesStandard neurologic examinationAdverse cognitive outcomesIncidence of deafnessDose indomethacinWeight infantsPreterm infantsProspective trialWeight neonatesCranial ultrasoundEarly administrationNeurodevelopmental outcomesNeurologic examinationCerebral palsyGestational age
1995
Antenatal steroids, delivery mode, and intraventricular hemorrhage in preterm infants
Ment L, Oh W, Ehrenkranz R, Philip A, Duncan C, Makuch R. Antenatal steroids, delivery mode, and intraventricular hemorrhage in preterm infants. American Journal Of Obstetrics And Gynecology 1995, 172: 795-800. PMID: 7892866, DOI: 10.1016/0002-9378(95)90001-2.Peer-Reviewed Original ResearchConceptsEarly intraventricular hemorrhageAntenatal steroidsIntraventricular hemorrhageCesarean sectionPreterm infantsAntenatal steroid treatmentCesarean section deliveryHours of lifeMore vaginal deliveriesDelivery modePostnatal indomethacinSection deliveryWeight infantsSteroid treatmentVaginal deliveryHemorrhageInfantsSteroidsIndependent roleHoursDeliveryMulticenterIndomethacinTrialsEchoencephalography
1994
Low-dose indomethacin therapy and extension of intraventricular hemorrhage: A multicenter randomized trial
Ment L, Oh W, Ehrenkranz R, Phillip A, Vohr B, Allan W, Makuch R, Taylor K, Schneider K, Katz K, Scott D, Duncan C. Low-dose indomethacin therapy and extension of intraventricular hemorrhage: A multicenter randomized trial. The Journal Of Pediatrics 1994, 124: 951-955. PMID: 8201485, DOI: 10.1016/s0022-3476(05)83191-9.Peer-Reviewed Original ResearchConceptsLow-grade intraventricular hemorrhageIntraventricular hemorrhageAdverse eventsBirth weightLow birth weight infantsDistribution of hemorrhageGrade intraventricular hemorrhageBirth weight infantsPlacebo-controlled trialPercentage of infantsPatent ductus arteriosusGm birth weightHours of ageIndomethacin therapyWeight infantsApgar scoreParenchymal involvementSaline placeboDuctus arteriosusGestational ageIntracranial hemorrhagePostnatal hoursCascade of eventsPatent ductusCranial sonogramsLow-dose indomethacin and prevention of intraventricular hemorrhage: a multicenter randomized trial.
Ment L, Ehrenkranz R, Duncan C, Scott D, Taylor K, Katz K, Schneider K, Makuch R, Oh W, Vohr B, Philip A, Allan W. Low-dose indomethacin and prevention of intraventricular hemorrhage: a multicenter randomized trial. Pediatrics 1994, 93: 543-50. PMID: 8134206, DOI: 10.1542/peds.93.4.543.Peer-Reviewed Original ResearchConceptsLow birth weight neonatesSeverity of IVHBirth weight neonatesIntraventricular hemorrhageWeight neonatesDose indomethacinBirth weightGrade 4 intraventricular hemorrhageSerial cranial ultrasound examinationsSignificant adverse drug eventsPercent of neonatesPlacebo-controlled trialPatent ductus arteriosusCranial ultrasound examinationMajor risk factorAdverse drug eventsHours of ageFirst postnatal dayDuctal closureProphylactic indomethacinApgar scoreNeurodevelopmental handicapParenchymal involvementPlacebo groupAdverse events
1993
Risk period for intraventricular hemorrhage of the preterm neonate is independent of gestational age.
Ment L, Oh W, Ehrenkranz R, Philip A, Schneider K, Katz K, Taylor K, Duncan C, Makuch R. Risk period for intraventricular hemorrhage of the preterm neonate is independent of gestational age. Seminars In Perinatology 1993, 17: 338-41. PMID: 8290976.Peer-Reviewed Original Research
1992
Risk factors for early intraventricular hemorrhage in low birth weight infants
Ment L, Oh W, Philip A, Ehrenkranz R, Duncan C, Allan W, Taylor K, Schneider K, Katz K, Makuch R. Risk factors for early intraventricular hemorrhage in low birth weight infants. The Journal Of Pediatrics 1992, 121: 776-783. PMID: 1432433, DOI: 10.1016/s0022-3476(05)81915-8.Peer-Reviewed Original ResearchConceptsGMH/IVHBirth weightRisk factorsIntraventricular hemorrhageLow birth weight infantsBirth weight infantsMaternal risk factorsGm birth weightMore vaginal deliveriesIndependent prognostic indicatorGerminal matrix hemorrhageHigh-grade hemorrhageRisk factor dataGroups of infantsMode of deliveryEarly intraventricular hemorrhagePrimary hospitalizationSevere IVHTocolytic useWeight infantsPreterm infantsVaginal deliveryVertex presentationGestational ageIVH group
1989
Survival in Children with Perinatally Acquired Human Immunodeficiency Virus Type 1 Infection
Scott G, Hutto C, Makuch R, Mastrucci M, O'Connor T, Mitchell C, Trapido E, Parks W. Survival in Children with Perinatally Acquired Human Immunodeficiency Virus Type 1 Infection. New England Journal Of Medicine 1989, 321: 1791-1796. PMID: 2594038, DOI: 10.1056/nejm198912283212604.Peer-Reviewed Original ResearchConceptsMedian survivalMedian ageHuman immunodeficiency virus type 1 (HIV-1) infectionHuman immunodeficiency virus type 1Virus type 1 infectionImmunodeficiency virus type 1Common first manifestationLymphoid interstitial pneumoniaIntravenous drug useProportional hazards analysisTime of diagnosisPneumocystis carinii pneumoniaHIV-1 infectionMedian survival timeType 1 infectionRecurrent bacterial infectionsJackson Memorial HospitalLong-term survivalYears of ageVirus type 1Candida esophagitisProgressive diseaseAntiviral treatmentBlood transfusionInterstitial pneumoniaGoodman and Kruskal's λ: A new look at an old measure of association
Makuch R, Rosenberg P, Scott G. Goodman and Kruskal's λ: A new look at an old measure of association. Statistics In Medicine 1989, 8: 619-631. PMID: 2727480, DOI: 10.1002/sim.4780080511.Peer-Reviewed Original Research