1987
myc family oncogene amplification in tumor cell lines established from small cell lung cancer patients and its relationship to clinical status and course.
Johnson B, Ihde D, Makuch R, Gazdar A, Carney D, Oie H, Russell E, Nau M, Minna J. myc family oncogene amplification in tumor cell lines established from small cell lung cancer patients and its relationship to clinical status and course. Journal Of Clinical Investigation 1987, 79: 1629-1634. PMID: 3034978, PMCID: PMC424486, DOI: 10.1172/jci112999.Peer-Reviewed Original ResearchConceptsMyc family DNA amplificationPatient tumorsTumor cell linesC-myc amplificationCell linesSmall cell lung cancer patientsCell lung cancer patientsSmall cell lung cancer cell linesCell lung cancer cell linesExtensive-stage patientsLung cancer patientsLung cancer cell linesCancer cell linesRelapsed patientsStage patientsClinical statusCancer patientsChemotherapy treatmentPatientsTumorsDNA amplificationOncogene amplification
1981
Association between human tumor colony-forming assay results and response of an individual patient's tumor to chemotherapy
Von Hoff D, Casper J, Bradley E, Sandbach J, Jones D, Makuch R. Association between human tumor colony-forming assay results and response of an individual patient's tumor to chemotherapy. The American Journal Of Medicine 1981, 70: 1027-1032. PMID: 7234870, DOI: 10.1016/0002-9343(81)90859-7.Peer-Reviewed Original ResearchConceptsIndividual patient's tumorPatient tumorsHuman tumorsGeneral oncology patientsParticular patient's tumorSeparate histologic typesProspective clinical trialsDrug sensitivity assaysColony-forming assaysHistologic typeOncology patientsClinical trialsPatient responsePatientsRetrospective mannerTumorsAntineoplastic agentsFluid specimenEnough cellsVivo resultsSensitivity assaysDrugsAssaysAssociationChemotherapy