2024
A deployable film method to enable replicable sampling of low-abundance environmental microbiomes
Mankiewicz Ledins P, Lin E, Bhattacharya C, Pollitt K, Dyson A, Hénaff E. A deployable film method to enable replicable sampling of low-abundance environmental microbiomes. Scientific Reports 2024, 14: 23857. PMID: 39394219, PMCID: PMC11470061, DOI: 10.1038/s41598-024-72341-y.Peer-Reviewed Original ResearchMeSH KeywordsDimethylpolysiloxanesDNA, BacterialEnvironmental MicrobiologyEnvironmental MonitoringHumansMicrobiotaSpecimen HandlingConceptsHuman healthPotential human health impactsHuman health impactsNegative long-term impactEnvironmental microbiomesTime indoorsEnvironmental nucleic acidsExposure studiesSequencing-based analysisChronic exposureHealth impactsHigher DNA yieldLong-term impactLow abundanceMicrobiome abundanceIndoor microbiome exposureSamplerMicrobiome samplesAbundanceIndoor microbiomeDNA yieldExtraction kitMicrobiomeSampling strategyGlobal population
2023
Assessment of children's personal and land use regression model-estimated exposure to NO2 in Springfield, Massachusetts
Gao D, Esenther S, Minet L, De Jesus A, Hudson S, Leaderer B, Hatzopoulou M, Godri Pollitt K. Assessment of children's personal and land use regression model-estimated exposure to NO2 in Springfield, Massachusetts. The Science Of The Total Environment 2023, 892: 164681. PMID: 37302586, DOI: 10.1016/j.scitotenv.2023.164681.Peer-Reviewed Original ResearchMeSH KeywordsAir PollutantsAir PollutionChildEnvironmental ExposureEnvironmental MonitoringHumansMassachusettsNitrogen DioxideSeasonsVehicle EmissionsWearable Passive Samplers for Assessing Environmental Exposure to Organic Chemicals: Current Approaches and Future Directions
Okeme J, Koelmel J, Johnson E, Lin E, Gao D, Pollitt K. Wearable Passive Samplers for Assessing Environmental Exposure to Organic Chemicals: Current Approaches and Future Directions. Current Environmental Health Reports 2023, 10: 84-98. PMID: 36821032, DOI: 10.1007/s40572-023-00392-w.Peer-Reviewed Original ResearchMeSH KeywordsAir PollutantsComplex MixturesEnvironmental ExposureEnvironmental MonitoringHumansVolatile Organic CompoundsConceptsPassive samplersOrganic chemicalsExposure assessmentHigh-throughput chemical analysisSemi-volatile organic chemicalsComplex mixturesChemical analysisEnvironmental health researchEnvironmental contaminantsPopulation scaleMonitoring approachActive air samplingQuantitative exposure assessmentEvaluation of exposureCompositional diversityAnalytical challengesHundreds of chemicalsPersonal exposurePopulation levelExposure estimatesSamplerActive samplersEnvironmental chemicalsContaminantsDynamic mixturePaired Indoor and Outdoor Nitrogen Dioxide Associated With Childhood Asthma Outcomes in a Mixed Rural-Urban Setting: A Feasibility Study
Wi C, Gent J, Bublitz J, King K, Ryu E, Sorrentino K, Plano J, McKay L, Porcher J, Wheeler P, Chiarella S, DeWan A, Pollitt K, Sheares B, Leaderer B, Juhn Y. Paired Indoor and Outdoor Nitrogen Dioxide Associated With Childhood Asthma Outcomes in a Mixed Rural-Urban Setting: A Feasibility Study. Journal Of Primary Care & Community Health 2023, 14: 21501319231173813. PMID: 37243352, PMCID: PMC10226331, DOI: 10.1177/21501319231173813.Peer-Reviewed Original ResearchMeSH KeywordsAir Pollution, IndoorAsthmaChildEnvironmental MonitoringFeasibility StudiesHumansNitrogen DioxideProspective StudiesConceptsAsthma control statusControl statusAsthma diaryRural-urban settingOutdoor NOChildhood asthma outcomesProspective cohort studySocioeconomic statusLow socioeconomic statusSmall feasibility studyAsthma exacerbationsOlmsted CountyPersistent asthmaAsthma outcomesCohort studyChildhood asthmaRural-urban communityLarger sample sizeAsthmaStudy periodHealth effectsFeasibility studyWeeksStatusLow threshold
2022
Unequal airborne exposure to toxic metals associated with race, ethnicity, and segregation in the USA
Kodros J, Bell M, Dominici F, L’Orange C, Godri Pollitt K, Weichenthal S, Wu X, Volckens J. Unequal airborne exposure to toxic metals associated with race, ethnicity, and segregation in the USA. Nature Communications 2022, 13: 6329. PMID: 36319637, PMCID: PMC9626599, DOI: 10.1038/s41467-022-33372-z.Peer-Reviewed Original ResearchCharacterizing the external exposome using passive samplers—comparative assessment of chemical exposures using different wearable form factors
Lin EZ, Nichols A, Zhou Y, Koelmel JP, Godri Pollitt KJ. Characterizing the external exposome using passive samplers—comparative assessment of chemical exposures using different wearable form factors. Journal Of Exposure Science & Environmental Epidemiology 2022, 33: 558-565. PMID: 35840784, DOI: 10.1038/s41370-022-00456-3.Peer-Reviewed Original ResearchMeSH KeywordsEnvironmental ExposureEnvironmental MonitoringExposomeHousehold ProductsHumansWearable Electronic DevicesConceptsPassive air samplersGas chromatography-high resolution mass spectrometryPassive samplersHigh-resolution mass spectrometryResolution mass spectrometryAirborne organic contaminantsAirborne chemical contaminantsOrganic contaminantsChemical exposureMass spectrometryAir samplerChemical contaminantsPersonal chemical exposureAirborne contaminantsActive samplersPersonal exposureContaminantsType of exposureSampler positionsEpidemiological studiesAirborne exposureExternal exposomeHousehold productsChestEnvironmental exposures
2021
Predicting Spatial Variations in Multiple Measures of PM2.5 Oxidative Potential and Magnetite Nanoparticles in Toronto and Montreal, Canada
Ripley S, Minet L, Zalzal J, Godri Pollitt K, Gao D, Lakey PSJ, Shiraiwa M, Maher BA, Hatzopoulou M, Weichenthal S. Predicting Spatial Variations in Multiple Measures of PM2.5 Oxidative Potential and Magnetite Nanoparticles in Toronto and Montreal, Canada. Environmental Science And Technology 2021, 56: 7256-7265. PMID: 34965092, DOI: 10.1021/acs.est.1c05364.Peer-Reviewed Original ResearchAssociation of Sulfur, Transition Metals, and the Oxidative Potential of Outdoor PM2.5 with Acute Cardiovascular Events: A Case-Crossover Study of Canadian Adults
Weichenthal S, Lavigne E, Traub A, Umbrio D, You H, Pollitt K, Shin T, Kulka R, Stieb DM, Korsiak J, Jessiman B, Brook JR, Hatzopoulou M, Evans G, Burnett RT. Association of Sulfur, Transition Metals, and the Oxidative Potential of Outdoor PM2.5 with Acute Cardiovascular Events: A Case-Crossover Study of Canadian Adults. Environmental Health Perspectives 2021, 129: 107005. PMID: 34644144, PMCID: PMC8513754, DOI: 10.1289/ehp9449.Peer-Reviewed Original ResearchConceptsAcute cardiovascular eventsCardiovascular eventsCase-crossover studyOdds ratioConditional logistic regression modelsFine particulate air pollutionLogistic regression modelsParticulate air pollutionStrength of associationCanadian adultsPopulation health risksObserved associationsRecent evidenceWeak associationOxidative potentialHealth impactsMenAssociationHealth risksMedian valueRegression modelsInfluence associationsAssociated health impactsSimilar patternOutdoor PM2.5Exposure to organophosphate esters in elderly people: Relationships of OPE body burdens with indoor air and dust concentrations and food consumption
Hou M, Fang J, Shi Y, Tang S, Dong H, Liu Y, Deng F, Giesy JP, Godri Pollitt KJ, Cai Y, Shi X. Exposure to organophosphate esters in elderly people: Relationships of OPE body burdens with indoor air and dust concentrations and food consumption. Environment International 2021, 157: 106803. PMID: 34365320, DOI: 10.1016/j.envint.2021.106803.Peer-Reviewed Original ResearchMeSH KeywordsAgedAir Pollution, IndoorBody BurdenChinaDustEnvironmental MonitoringEstersFlame RetardantsHumansOrganophosphatesConceptsElderly peopleHealth effectsWhole bloodFood frequency questionnaireHealthy elderly peopleHigh blood concentrationsBw/dayDaily total intakeAdverse health effectsHigher consumption frequencyTnBP exposureFrequency questionnaireIndoor dustPotential health effectsUrinary levelsBlood concentrationsDietary exposure pathwaysElderly populationOPE exposureExcretory capacityTotal intakeExposure pathwaysSuitable biomarkersBloodConsumption frequencyPredicting Spatial Variations in Multiple Measures of Oxidative Burden for Outdoor Fine Particulate Air Pollution across Canada
Xu JW, Martin RV, Evans GJ, Umbrio D, Traub A, Meng J, van Donkelaar A, You H, Kulka R, Burnett RT, Pollitt K, Weichenthal S. Predicting Spatial Variations in Multiple Measures of Oxidative Burden for Outdoor Fine Particulate Air Pollution across Canada. Environmental Science And Technology 2021, 55: 9750-9760. PMID: 34241996, DOI: 10.1021/acs.est.1c01210.Peer-Reviewed Original ResearchExploring personal chemical exposures in China with wearable air pollutant monitors: A repeated-measure study in healthy older adults in Jinan, China
Guo P, Lin EZ, Koelmel JP, Ding E, Gao Y, Deng F, Dong H, Liu Y, Cha Y, Fang J, Shi X, Tang S, Godri Pollitt KJ. Exploring personal chemical exposures in China with wearable air pollutant monitors: A repeated-measure study in healthy older adults in Jinan, China. Environment International 2021, 156: 106709. PMID: 34153889, DOI: 10.1016/j.envint.2021.106709.Peer-Reviewed Original ResearchMeSH KeywordsAgedAir PollutantsChinaEnvironmental MonitoringGas Chromatography-Mass SpectrometryHumansWearable Electronic DevicesConceptsVolatile organic compoundsPolycyclic aromatic hydrocarbonsAirborne chemical contaminantsPersonal exposure profilesPassive air samplersOrganic compoundsPassive samplersChemical classesChemical contaminantsChemical analysisPersonal chemical exposureCertain polycyclic aromatic hydrocarbonsChemical exposureAirborne compoundsAirborne contaminantsCompoundsAromatic hydrocarbonsContaminantsAir monitoring sitesComprehensive characterizationPhthalateNitroaromaticsRepeated-measures studyAir samplerNitrobenzeneFluoroMatch 2.0—making automated and comprehensive non-targeted PFAS annotation a reality
Koelmel JP, Stelben P, McDonough CA, Dukes DA, Aristizabal-Henao JJ, Nason SL, Li Y, Sternberg S, Lin E, Beckmann M, Williams AJ, Draper J, Finch JP, Munk JK, Deigl C, Rennie EE, Bowden JA, Godri Pollitt KJ. FluoroMatch 2.0—making automated and comprehensive non-targeted PFAS annotation a reality. Analytical And Bioanalytical Chemistry 2021, 414: 1201-1215. PMID: 34014358, PMCID: PMC10228292, DOI: 10.1007/s00216-021-03392-7.Peer-Reviewed Original ResearchChromatography, LiquidEnvironmental MonitoringEnvironmental PollutantsFluorocarbonsSoftwareTandem Mass SpectrometryHead, Shoulders, Knees, and Toes: Placement of Wearable Passive Samplers Alters Exposure Profiles Observed
Koelmel JP, Lin EZ, Nichols A, Guo P, Zhou Y, Pollitt K. Head, Shoulders, Knees, and Toes: Placement of Wearable Passive Samplers Alters Exposure Profiles Observed. Environmental Science And Technology 2021, 55: 3796-3806. PMID: 33625210, DOI: 10.1021/acs.est.0c05522.Peer-Reviewed Original ResearchMeSH KeywordsEnvironmental MonitoringHumansShoulderToesVolatile Organic CompoundsWearable Electronic DevicesConceptsSemivolatile organic compoundsOrganic compoundsGas chromatography-high resolution mass spectrometryPassive samplersHigh-resolution mass spectrometryVolatile organic compoundsPersonal exposure profilesChemicals of concernMass spectrometryChemicalsExposure dynamicsExposure profilesCompoundsMajor risk factorComprehensive characterizationPersonal exposureAirborne contaminantsContaminant exposureRisk factorsInhalation routeEpidemiological studiesChemical exposureSpectrometrySamplerParticipants' wrists
2020
Exploring the external exposome using wearable passive samplers - The China BAPE study
Koelmel JP, Lin EZ, Guo P, Zhou J, He J, Chen A, Gao Y, Deng F, Dong H, Liu Y, Cha Y, Fang J, Beecher C, Shi X, Tang S, Godri Pollitt KJ. Exploring the external exposome using wearable passive samplers - The China BAPE study. Environmental Pollution 2020, 270: 116228. PMID: 33360595, DOI: 10.1016/j.envpol.2020.116228.Peer-Reviewed Original ResearchMeSH KeywordsAgedAir PollutantsChinaEnvironmental MonitoringExposomeHumansMiddle AgedWearable Electronic DevicesConceptsPassive samplersPersonal care productsPersonal exposure profilesAirborne contaminant exposurePassive air samplersChemicals of concernToxicity of chemicalsPolyaromatic hydrocarbonsCare productsChina BAPE studyElevated toxicityPersonal exposureChemicalsSources of exposureParticulate phaseInhalation routeExternal exposomeGreater health risksCigarette smokeContaminant exposureAntimicrobial soapHealthy participantsRouteAir samplerEnvironmental exposures
2018
Long-term leaching of arsenic from pressure-treated playground structures in the northeastern United States
Deramos King CM, Dozier CS, Campbell JL, Curry ED, Godri Pollitt KJ. Long-term leaching of arsenic from pressure-treated playground structures in the northeastern United States. The Science Of The Total Environment 2018, 656: 834-842. PMID: 30530151, DOI: 10.1016/j.scitotenv.2018.11.315.Peer-Reviewed Original ResearchFine Particulate Air Pollution and Adverse Birth Outcomes: Effect Modification by Regional Nonvolatile Oxidative Potential
Lavigne É, Burnett RT, Stieb DM, Evans GJ, Godri Pollitt KJ, Chen H, van Rijswijk D, Weichenthal S. Fine Particulate Air Pollution and Adverse Birth Outcomes: Effect Modification by Regional Nonvolatile Oxidative Potential. Environmental Health Perspectives 2018, 126: 077012. PMID: 30073952, PMCID: PMC6108848, DOI: 10.1289/ehp2535.Peer-Reviewed Original ResearchConceptsTerm low birth weightLow birth weightAdverse birth outcomesPreterm birthBirth outcomesHighest quartileBirth weightEffect modificationFirst trimester PMRetrospective cohort studyTerm birth weightFine particulate air pollutionPossible effect modificationDays of deliveryFine particulate matter air pollutionParticulate matter air pollutionMatter air pollutionEffects of PMEstimate of effectParticulate air pollutionPreterm deliveryCohort studySingleton birthsPrenatal exposureImpact of PM
2017
Biomonitoring-based exposure assessment of benzene, toluene, ethylbenzene and xylene among workers at petroleum distribution facilities
Heibati B, Pollitt K, Charati JY, Ducatman A, Shokrzadeh M, Karimi A, Mohammadyan M. Biomonitoring-based exposure assessment of benzene, toluene, ethylbenzene and xylene among workers at petroleum distribution facilities. Ecotoxicology And Environmental Safety 2017, 149: 19-25. PMID: 29145162, DOI: 10.1016/j.ecoenv.2017.10.070.Peer-Reviewed Original ResearchConceptsGas chromatography-mass spectrometrySolid-phase microextractionChromatography-mass spectrometryVolatile organic compoundsOrganic compoundsPpb tolueneMass spectrometryPassive samplersPersonal passive samplersConcentrations of BTEXPpb benzeneBenzeneBTEX compoundsTolueneUrinary BTEX levelsOil distribution companyPersonal exposureXylenePersonal air exposuresBTEXCompoundsEthylbenzeneOccupational health concernAir exposureRapid methodBTEX exposure assessment and quantitative risk assessment among petroleum product distributors
Heibati B, Pollitt KJG, Karimi A, Charati J, Ducatman A, Shokrzadeh M, Mohammadyan M. BTEX exposure assessment and quantitative risk assessment among petroleum product distributors. Ecotoxicology And Environmental Safety 2017, 144: 445-449. PMID: 28666218, DOI: 10.1016/j.ecoenv.2017.06.055.Peer-Reviewed Original ResearchMeSH KeywordsAir Pollutants, OccupationalEnvironmental MonitoringHumansIranNeoplasmsOccupational ExposurePetroleumRisk AssessmentWorkplaceConceptsHigh-risk occupationsOccupational exposure limitsExcess riskCancer riskXylene exposureExcess lifetime cancer riskRisk occupationsHealth of workersGovernmental Industrial HygienistsLifetime cancer riskExposure assessmentExposure limitsIndustrial HygienistsRiskAmerican ConferenceExposureExposure samplesHazard quotientMean concentrationMaximum mean concentrationRisk assessmentMean valueQuantitative risk assessmentStrong contributorWorkersAssessment of indoor and outdoor particulate air pollution at an urban background site in Iran
Mohammadyan M, Ghoochani M, Kloog I, Abdul-Wahab SA, Yetilmezsoy K, Heibati B, Godri Pollitt KJ. Assessment of indoor and outdoor particulate air pollution at an urban background site in Iran. Environmental Monitoring And Assessment 2017, 189: 235. PMID: 28451957, DOI: 10.1007/s10661-017-5951-1.Peer-Reviewed Original ResearchMeSH KeywordsAir PollutantsAir Pollution, IndoorDeveloping CountriesEnvironmental MonitoringHumansIranParticle SizeParticulate MatterScienceUniversities
2016
Trace metal exposure is associated with increased exhaled nitric oxide in asthmatic children
Godri Pollitt KJ, Maikawa CL, Wheeler AJ, Weichenthal S, Dobbin NA, Liu L, Goldberg MS. Trace metal exposure is associated with increased exhaled nitric oxide in asthmatic children. Environmental Health 2016, 15: 94. PMID: 27586245, PMCID: PMC5009709, DOI: 10.1186/s12940-016-0173-5.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAir PollutantsArsenicAsthmaChildEnvironmental MonitoringExhalationFemaleHumansMaleMetalsNitric OxideParticulate MatterConceptsAsthmatic childrenIQR increaseNitric oxideEmergency room visitsExacerbation of symptomsPersonal daily exposureAcute health effectsResultsA positive associationElevated FeNOFeNO responseAirway inflammationRoom visitsMarker of trafficDaily exposureAsthma experienceConsecutive daysFeNOChildren's exposureHealth effectsPersonal samplesChildrenPositive associationExposureFine particulate matterAmbient PM2.5