Trace metal exposure is associated with increased exhaled nitric oxide in asthmatic children
Godri Pollitt KJ, Maikawa CL, Wheeler AJ, Weichenthal S, Dobbin NA, Liu L, Goldberg MS. Trace metal exposure is associated with increased exhaled nitric oxide in asthmatic children. Environmental Health 2016, 15: 94. PMID: 27586245, PMCID: PMC5009709, DOI: 10.1186/s12940-016-0173-5.Peer-Reviewed Original ResearchConceptsAsthmatic childrenIQR increaseNitric oxideEmergency room visitsExacerbation of symptomsPersonal daily exposureAcute health effectsResultsA positive associationElevated FeNOFeNO responseAirway inflammationRoom visitsMarker of trafficDaily exposureAsthma experienceConsecutive daysFeNOChildren's exposureHealth effectsPersonal samplesChildrenPositive associationExposureFine particulate matterAmbient PM2.5Particulate Oxidative Burden as a Predictor of Exhaled Nitric Oxide in Children with Asthma
Maikawa CL, Weichenthal S, Wheeler AJ, Dobbin NA, Smargiassi A, Evans G, Liu L, Goldberg MS, Pollitt KJ. Particulate Oxidative Burden as a Predictor of Exhaled Nitric Oxide in Children with Asthma. Environmental Health Perspectives 2016, 124: 1616-1622. PMID: 27152705, PMCID: PMC5047770, DOI: 10.1289/ehp175.Peer-Reviewed Original ResearchOxidative burdenAirway inflammationNitric oxideAsthmatic school-aged childrenExhaled Nitric OxideReactive oxygen speciesPM2.5 personal exposureFeNO levelsFeNO responseCorticosteroid useAsthmatic symptomsAsthmatic childrenSchool-aged childrenRespiratory tractOxygen speciesEpidemiological studiesFeNOFluid liningConsecutive daysPersonal exposurePersonal exposure samplesAsthmaBurdenAllergyChildren