2023
Within-city spatial variations in long-term average outdoor oxidant gas concentrations and cardiovascular mortality: Effect modification by oxidative potential in the Canadian Census Health and Environment Cohort
Ripley S, Gao D, Pollitt K, Lakey P, Shiraiwa M, Hatzopoulou M, Weichenthal S. Within-city spatial variations in long-term average outdoor oxidant gas concentrations and cardiovascular mortality: Effect modification by oxidative potential in the Canadian Census Health and Environment Cohort. Environmental Epidemiology 2023, 7: e257. PMID: 37545813, PMCID: PMC10403014, DOI: 10.1097/ee9.0000000000000257.Peer-Reviewed Original ResearchCanadian Census HealthCardiovascular mortalityReactive oxygen species concentrationParticulate air pollutionEnvironment CohortMeasures of PMRetrospective cohort studyFine particulate air pollutionRelevant confounding factorsProportional hazards modelOutdoor fine particulate air pollutionPopulation health impactHealth impactsCardiovascular health impactsOutdoor air pollutionCardiovascular deathCohort studyOxidant gasesEffect modificationHazards modelConfounding factorsMortalityOxidative stressHealth effectsOxidative potentialPaired Indoor and Outdoor Nitrogen Dioxide Associated With Childhood Asthma Outcomes in a Mixed Rural-Urban Setting: A Feasibility Study
Wi C, Gent J, Bublitz J, King K, Ryu E, Sorrentino K, Plano J, McKay L, Porcher J, Wheeler P, Chiarella S, DeWan A, Pollitt K, Sheares B, Leaderer B, Juhn Y. Paired Indoor and Outdoor Nitrogen Dioxide Associated With Childhood Asthma Outcomes in a Mixed Rural-Urban Setting: A Feasibility Study. Journal Of Primary Care & Community Health 2023, 14: 21501319231173813. PMID: 37243352, PMCID: PMC10226331, DOI: 10.1177/21501319231173813.Peer-Reviewed Original ResearchConceptsAsthma control statusControl statusAsthma diaryRural-urban settingOutdoor NOChildhood asthma outcomesProspective cohort studySocioeconomic statusLow socioeconomic statusSmall feasibility studyAsthma exacerbationsOlmsted CountyPersistent asthmaAsthma outcomesCohort studyChildhood asthmaRural-urban communityLarger sample sizeAsthmaStudy periodHealth effectsFeasibility studyWeeksStatusLow threshold
2022
Long-term Exposure to Oxidant Gases and Mortality: Effect Modification by PM2.5 Transition Metals and Oxidative Potential
Toyib O, Lavigne E, Traub A, Umbrio D, You H, Ripley S, Pollitt K, Shin T, Kulka R, Jessiman B, Tjepkema M, Martin R, Stieb DM, Hatzopoulou M, Evans G, Burnett RT, Weichenthal S. Long-term Exposure to Oxidant Gases and Mortality: Effect Modification by PM2.5 Transition Metals and Oxidative Potential. Epidemiology 2022, 33: 767-776. PMID: 36165987, PMCID: PMC9531968, DOI: 10.1097/ede.0000000000001538.Peer-Reviewed Original ResearchConceptsLong-term exposureOxidative stressFine particulate air pollutionProportional hazards modelAir pollution health effectsHealth impactsObserved health impactsParticulate air pollutionCohort studyMortality outcomesOxidant gasesEffect modificationInterquartile increaseHazards modelAdverse health impactsNonaccidental mortalityGSH levelsHealth effectsMortalityLand use regression modelsOxidative potentialMedianRegression modelsExposurePM 2.5
2021
Telomere length and outcome of treatment for pulmonary tuberculosis in a gold mining community
Katoto PDMC, Kayembe-Kitenge T, Pollitt KJG, Martens DS, Ghosh M, Nachega JB, Nemery B, Nawrot TS. Telomere length and outcome of treatment for pulmonary tuberculosis in a gold mining community. Scientific Reports 2021, 11: 4031. PMID: 33597559, PMCID: PMC7889934, DOI: 10.1038/s41598-021-83281-2.Peer-Reviewed Original ResearchConceptsTreatment outcomesPTB patientsTelomere lengthActive pulmonary tuberculosis patientsMtDNA contentOutpatient TB clinicSuccessful TB treatmentProspective cohort studyPulmonary tuberculosis patientsTime of diagnosisOutcome of treatmentBlood mtDNA contentRural Democratic RepublicPeripheral blood leukocytesShorter telomere lengthLonger telomere lengthRelative telomere lengthHIV coinfectionTB clinicCohort studyPulmonary tuberculosisTB treatmentTuberculosis patientsPTB outcomesBlood leukocytes
2018
Fine Particulate Air Pollution and Adverse Birth Outcomes: Effect Modification by Regional Nonvolatile Oxidative Potential
Lavigne É, Burnett RT, Stieb DM, Evans GJ, Godri Pollitt KJ, Chen H, van Rijswijk D, Weichenthal S. Fine Particulate Air Pollution and Adverse Birth Outcomes: Effect Modification by Regional Nonvolatile Oxidative Potential. Environmental Health Perspectives 2018, 126: 077012. PMID: 30073952, PMCID: PMC6108848, DOI: 10.1289/ehp2535.Peer-Reviewed Original ResearchConceptsTerm low birth weightLow birth weightAdverse birth outcomesPreterm birthBirth outcomesHighest quartileBirth weightEffect modificationFirst trimester PMRetrospective cohort studyTerm birth weightFine particulate air pollutionPossible effect modificationDays of deliveryFine particulate matter air pollutionParticulate matter air pollutionMatter air pollutionEffects of PMEstimate of effectParticulate air pollutionPreterm deliveryCohort studySingleton birthsPrenatal exposureImpact of PM