2023
Novel perfluoroalkyl substances (PFAS) discovered in whole blood using automated non-targeted analysis of dried blood spots
Koelmel J, Lin E, Parry E, Stelben P, Rennie E, Godri Pollitt K. Novel perfluoroalkyl substances (PFAS) discovered in whole blood using automated non-targeted analysis of dried blood spots. The Science Of The Total Environment 2023, 883: 163579. PMID: 37100129, PMCID: PMC10247435, DOI: 10.1016/j.scitotenv.2023.163579.Peer-Reviewed Original ResearchMeSH KeywordsCarboxylic AcidsChromatography, LiquidEthersFemaleFluorocarbonsHumansInfant, NewbornPregnancyTandem Mass SpectrometryConceptsBlood spotsNovel perfluoroalkyl substancesHuman bloodVenous blood drawBlood spot cardsBlood spot samplesPerfluoroalkyl substancesPrenatal exposureBlood drawEnvironmental epidemiology studiesEpidemiology studiesFalse negative rateBloodLow false negative rateInvasive collection techniquesWhole bloodVulnerable populationsLiquid chromatography-high resolution tandem mass spectrometryUnderstanding of exposureSpot samplesSpot cardsHigh-resolution tandem mass spectrometryExposurePerfluoroalkyl ether carboxylic acidsScreening
2022
Occurrence and contamination profile of legacy and emerging per- and polyfluoroalkyl substances (PFAS) in Belgian wastewater using target, suspect and non-target screening approaches
Jeong Y, Da Silva KM, Iturrospe E, Fuiji Y, Boogaerts T, van Nuijs ALN, Koelmel J, Covaci A. Occurrence and contamination profile of legacy and emerging per- and polyfluoroalkyl substances (PFAS) in Belgian wastewater using target, suspect and non-target screening approaches. Journal Of Hazardous Materials 2022, 437: 129378. PMID: 35897185, DOI: 10.1016/j.jhazmat.2022.129378.Peer-Reviewed Original ResearchConceptsWastewater treatment plantsTreatment plantsAqueous filmMass loadNon-target screening approachPolyfluoroalkyl substancesWastewaterComprehensive investigationFoamPerfluorooctanoic acidFluorotelomer carboxylic acidFilmsHigher valuesPerfluorobutanoic acidPredominant PFASsLoadNon-target screeningConfidence levelCatchment areaNon-target screening method
2021
FluoroMatch 2.0—making automated and comprehensive non-targeted PFAS annotation a reality
Koelmel JP, Stelben P, McDonough CA, Dukes DA, Aristizabal-Henao JJ, Nason SL, Li Y, Sternberg S, Lin E, Beckmann M, Williams AJ, Draper J, Finch JP, Munk JK, Deigl C, Rennie EE, Bowden JA, Godri Pollitt KJ. FluoroMatch 2.0—making automated and comprehensive non-targeted PFAS annotation a reality. Analytical And Bioanalytical Chemistry 2021, 414: 1201-1215. PMID: 34014358, PMCID: PMC10228292, DOI: 10.1007/s00216-021-03392-7.Peer-Reviewed Original Research
2017
Tissue distribution of perfluoroalkyl acids and health status in wild Mozambique tilapia (Oreochromis mossambicus) from Loskop Dam, Mpumalanga, South Africa
Bangma J, Reiner J, Botha H, Cantu T, Gouws M, Guillette M, Koelmel J, Luus-Powell W, Myburgh J, Rynders O, Sara J, Smit W, Bowden J. Tissue distribution of perfluoroalkyl acids and health status in wild Mozambique tilapia (Oreochromis mossambicus) from Loskop Dam, Mpumalanga, South Africa. Journal Of Environmental Sciences 2017, 61: 59-67. PMID: 29191316, PMCID: PMC6584947, DOI: 10.1016/j.jes.2017.03.041.Peer-Reviewed Original ResearchConceptsHealth statusInflammatory diseasesFish health statusAdipose tissueHealthy tilapiaTissue distributionTissue concentrationsPerfluoroalkyl acidsMale Mozambique tilapiaKidneyPerfluorooctanoic acidTissueBurdenLiverHigher PFAA concentrationsPerfluorooctanesulfonic acidStatusOrgansMozambique tilapiaPFAA concentrationsStatistical analysisSpleenIncidenceDiseaseCare