2019
Lipidomics for wildlife disease etiology and biomarker discovery: a case study of pansteatitis outbreak in South Africa
Koelmel J, Ulmer C, Fogelson S, Jones C, Botha H, Bangma J, Guillette T, Luus-Powell W, Sara J, Smit W, Albert K, Miller H, Guillette M, Olsen B, Cochran J, Garrett T, Yost R, Bowden J. Lipidomics for wildlife disease etiology and biomarker discovery: a case study of pansteatitis outbreak in South Africa. Metabolomics 2019, 15: 38. PMID: 30838461, PMCID: PMC11005104, DOI: 10.1007/s11306-019-1490-9.Peer-Reviewed Original ResearchConceptsApplication of lipidomicsDiverse biological rolesWildlife studiesPossible disease mechanismsClasses of lipidsHigh-resolution tandem mass spectrometryLoskop DamBiological roleMozambique tilapiaCell deathMortality eventsPansteatitisLipidomicsOxidative damageDisease mechanismsAdipose tissuePromising biomarker candidatesBiomarker discoveryDisease etiologyTilapiaTandem mass spectrometryCeramideAquatic lifeLipidomeBiomarker candidates
2017
Tissue distribution of perfluoroalkyl acids and health status in wild Mozambique tilapia (Oreochromis mossambicus) from Loskop Dam, Mpumalanga, South Africa
Bangma J, Reiner J, Botha H, Cantu T, Gouws M, Guillette M, Koelmel J, Luus-Powell W, Myburgh J, Rynders O, Sara J, Smit W, Bowden J. Tissue distribution of perfluoroalkyl acids and health status in wild Mozambique tilapia (Oreochromis mossambicus) from Loskop Dam, Mpumalanga, South Africa. Journal Of Environmental Sciences 2017, 61: 59-67. PMID: 29191316, PMCID: PMC6584947, DOI: 10.1016/j.jes.2017.03.041.Peer-Reviewed Original ResearchConceptsHealth statusInflammatory diseasesFish health statusAdipose tissueHealthy tilapiaTissue distributionTissue concentrationsPerfluoroalkyl acidsMale Mozambique tilapiaKidneyPerfluorooctanoic acidTissueBurdenLiverHigher PFAA concentrationsPerfluorooctanesulfonic acidStatusOrgansMozambique tilapiaPFAA concentrationsStatistical analysisSpleenIncidenceDiseaseCare