2014
Methylmercury-Induced Inhibition of Paraoxonase-1 (PON1)—Implications for Cardiovascular Risk
Ginsberg G, Sonawane B, Nath R, Lewandowski P. Methylmercury-Induced Inhibition of Paraoxonase-1 (PON1)—Implications for Cardiovascular Risk. Journal Of Toxicology And Environmental Health Part A 2014, 77: 1004-1023. PMID: 25072822, DOI: 10.1080/15287394.2014.919837.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntioxidantsAryldialkylphosphataseCarboxylic Ester HydrolasesCardiovascular DiseasesDisease Models, AnimalDose-Response Relationship, DrugFatty Acids, Omega-3FishesFood ContaminationHumansLipid MetabolismMeatMethylmercury CompoundsMiceReactive Oxygen SpeciesRisk AssessmentRisk FactorsConceptsCardiovascular riskParaoxonase 1PON1 activityDoses of MeHgAcute cardiovascular eventsSerum PON1 activityHigh-density lipoproteinCardiovascular eventsBlood lipidsMeHg doseCardiovascular healthFish-eating populationsCardiovascular diseaseCardioprotective factorPON1 levelsVascular endotheliumDisease processEpidemiology studiesClinical biomarkersPopulation riskBiochemical effectsAntioxidant defenseRiskFish consumptionDisease biomarkers
2000
Development of a single-meal fish consumption advisory for methyl mercury.
Ginsberg G, Toal B. Development of a single-meal fish consumption advisory for methyl mercury. Risk Analysis 2000, 20: 41-7. PMID: 10795337, DOI: 10.1111/0272-4332.00004.Peer-Reviewed Original ResearchConceptsFish consumption advisoriesMaternal hair concentrationsConsumption advisoriesMethyl mercuryHair concentrationsU.S. Environmental Protection Agency reference doseEnvironmental Protection Agency reference doseFish MeHg concentrationsMercury hair concentrationFish tissue concentrationsMeHg body burdenAcute exposure to MeHgContamination of fishExposure to MeHgFish sampling programSingle-meal scenariosMeHg concentrationsRfD levelFish concentrationsBody burdenFish consumptionReference doseMeHgSampling programSeasonal differences