2014
Methylmercury-Induced Inhibition of Paraoxonase-1 (PON1)—Implications for Cardiovascular Risk
Ginsberg G, Sonawane B, Nath R, Lewandowski P. Methylmercury-Induced Inhibition of Paraoxonase-1 (PON1)—Implications for Cardiovascular Risk. Journal Of Toxicology And Environmental Health Part A 2014, 77: 1004-1023. PMID: 25072822, DOI: 10.1080/15287394.2014.919837.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntioxidantsAryldialkylphosphataseCarboxylic Ester HydrolasesCardiovascular DiseasesDisease Models, AnimalDose-Response Relationship, DrugFatty Acids, Omega-3FishesFood ContaminationHumansLipid MetabolismMeatMethylmercury CompoundsMiceReactive Oxygen SpeciesRisk AssessmentRisk FactorsConceptsCardiovascular riskParaoxonase 1PON1 activityDoses of MeHgAcute cardiovascular eventsSerum PON1 activityHigh-density lipoproteinCardiovascular eventsBlood lipidsMeHg doseCardiovascular healthFish-eating populationsCardiovascular diseaseCardioprotective factorPON1 levelsVascular endotheliumDisease processEpidemiology studiesClinical biomarkersPopulation riskBiochemical effectsAntioxidant defenseRiskFish consumptionDisease biomarkers
2012
Cadmium Risk Assessment in Relation to Background Risk of Chronic Kidney Disease
Ginsberg GL. Cadmium Risk Assessment in Relation to Background Risk of Chronic Kidney Disease. Journal Of Toxicology And Environmental Health Part A 2012, 75: 374-390. PMID: 22524593, DOI: 10.1080/15287394.2012.670895.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedCadmiumDose-Response Relationship, DrugEnvironmental ExposureFemaleFood ContaminationGlomerular Filtration RateHumansMiddle AgedModels, BiologicalRenal Insufficiency, ChronicRisk AssessmentConceptsChronic kidney diseaseKidney diseaseU.S. Environmental Protection Agency reference dosesStage 3 chronic kidney diseaseNoncancer effectsPopulation riskCurrent dietary exposureMinimum risk levelLower Cd doseCKD riskDisease Registry's Minimum Risk LevelDaily doseLow doseChronic daily doseSwedish womenDietary exposureLeft shiftAdverse effectsCd doseDiseaseCadmium risk assessmentDoseReference dosesDose responseGFR