2005
Increasing Risk of 5% or Greater Unintentional Weight Loss in a Cohort of HIV-Infected Patients, 1995 to 2003
Tang AM, Jacobson DL, Spiegelman D, Knox TA, Wanke C. Increasing Risk of 5% or Greater Unintentional Weight Loss in a Cohort of HIV-Infected Patients, 1995 to 2003. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2005, 40: 70-76. PMID: 16123685, DOI: 10.1097/01.qai.0000159627.54149.2e.Peer-Reviewed Original ResearchConceptsCohort of HIVUnintentional weight lossWeight lossAntiretroviral therapyBody compositionLow CD4 cell countsHigher HIV viral loadHigher body mass indexCare of HIVHealthy Living cohortActive antiretroviral therapyCD4 cell countCombination antiretroviral therapyHIV viral loadBody mass indexRisk of deathPresence of diarrheaFederal poverty levelLiving cohortHIV infectionMass indexMost AIDSOpportunistic infectionsViral loadPatient populationA Comparison of the Clinical and Cost-Effectiveness of 3 Intervention Strategies for AIDS Wasting
Shevitz AH, Wilson IB, McDermott AY, Spiegelman D, Skinner SC, Antonsson K, Layne JE, Beaston-Blaakman A, Shepard DS, Gorbach SL. A Comparison of the Clinical and Cost-Effectiveness of 3 Intervention Strategies for AIDS Wasting. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2005, 38: 399-406. PMID: 15764956, DOI: 10.1097/01.qai.0000152647.89008.2b.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnabolic AgentsAntiretroviral Therapy, Highly ActiveBody CompositionCost-Benefit AnalysisDietFemaleHealth StatusHIV Wasting SyndromeHumansMaleMassachusettsMiddle AgedMuscle, SkeletalNutritional Physiological PhenomenaOxandrolonePhysical Education and TrainingQuality of LifeTreatment OutcomeConceptsProgressive resistance trainingCross-sectional muscle areaPhysical functioningCost-effective interventionAIDS wastingLeast cost-effective interventionBaseline physical functioningQuality of lifeInstitutional costsPlacebo pillsResistance trainingCaloric intakeProtein intakeBody compositionStrength training
2002
Changes in lean body mass and total body weight are weakly associated with physical functioning in patients with HIV infection
Wilson I, Jacobson D, Roubenoff R, Spiegelman D, Knox T, Gorbach S. Changes in lean body mass and total body weight are weakly associated with physical functioning in patients with HIV infection. HIV Medicine 2002, 3: 263-270. PMID: 12444944, DOI: 10.1046/j.1468-1293.2002.00122.x.Peer-Reviewed Original ResearchConceptsTotal body weightSelf-reported physical functioningPhysical functioningHIV infectionBody weightRelationship of changesCells/ micro l.Mean CD4 countHIV-positive personsMain outcome measuresLean body massLongitudinal analysisCD4 countCohort studyPositive personsOutcome measuresHealthy personsBody compositionPatientsStudy designWeight lossMicro l.InfectionWomenHealthy living
2001
Weight and body composition in a cohort of HIV-positive men and women
Forrester J, Spiegelman D, Woods M, Knox T, Fauntleroy J, Gorbach S. Weight and body composition in a cohort of HIV-positive men and women. Public Health Nutrition 2001, 4: 743-747. PMID: 11415480, DOI: 10.1079/phn200099.Peer-Reviewed Original Research
2000
Body Composition and Dietary Intake in Relation to Drug Abuse in a Cohort of HIV-Positive Persons
Forrester J, Woods M, Knox T, Spiegelman D, Skinner S, Gorbach S. Body Composition and Dietary Intake in Relation to Drug Abuse in a Cohort of HIV-Positive Persons. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2000, 25: s43-s48. PMID: 11126426, DOI: 10.1097/00042560-200010001-00007.Peer-Reviewed Original ResearchConceptsBody mass indexIntravenous drug usersBody compositionDrug usersEnergy intakeDietary intakeFat massCurrent intravenous drug usersPast intravenous drug usersDrug abuseSelf-reported energy intakeHIV-positive personsHigher energy intakeBioelectrical impedance analysisCross-sectional analysisDrug use categoriesDrug use groupHIV infectionMass indexFood recordsDietary dataNonintravenous drugsNutritional statusIntakeWomenBody Composition and Dietary Intake in Relation to Drug Abuse in a Cohort of HIV-Positive Persons
Forrester J, Woods M, Knox T, Spiegelman D, Skinner S, Gorbach S. Body Composition and Dietary Intake in Relation to Drug Abuse in a Cohort of HIV-Positive Persons. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2000, 25: s43-s48. DOI: 10.1097/00126334-200010001-00007.Peer-Reviewed Original ResearchBody mass indexIntravenous drug usersBody compositionDrug usersEnergy intakeDietary intakeFat massCurrent intravenous drug usersPast intravenous drug usersDrug abuseSelf-reported energy intakeHIV-positive personsHigher energy intakeBioelectrical impedance analysisCross-sectional analysisDrug use categoriesDrug use groupHIV infectionMass indexFood recordsDietary dataNonintravenous drugsNutritional statusIntakeWomen
1998
The effect of protease inhibitors on weight and body composition in HIV-infected patients
Silva M, Skolnik P, Gorbach S, Spiegelman D, Wilson I, Fernández-DiFranco M, Knox T. The effect of protease inhibitors on weight and body composition in HIV-infected patients. AIDS 1998, 12: 1645-1651. PMID: 9764784, DOI: 10.1097/00002030-199813000-00012.Peer-Reviewed Original ResearchConceptsLean body massPI therapyHIV infectionWeight gainViral loadPhysical functioningHealth perceptionBody compositionCurrent health perceptionsActive antiretroviral therapyPI treatmentProtease inhibitor therapyBody mass indexGreater weight gainHuman growth hormoneAntiretroviral therapyHIV cohortBody massInhibitor therapyMass indexOptimal therapyFat massAnabolic stimuliPatientsGrowth hormone
1992
Absolute fat mass, percent body fat, and body-fat distribution: which is the real determinant of blood pressure and serum glucose?
Spiegelman D, Israel R, Bouchard C, Willett W. Absolute fat mass, percent body fat, and body-fat distribution: which is the real determinant of blood pressure and serum glucose? American Journal Of Clinical Nutrition 1992, 55: 1033-1044. PMID: 1595574, DOI: 10.1093/ajcn/55.6.1033.Peer-Reviewed Original ResearchConceptsBody mass indexBlood pressurePercent body fatAbsolute fat massFat massSerum glucoseBody fatBlood glucoseDiastolic blood pressureBody fat distributionCigarette smoking statusCurrent cigarette smoking statusRegional fat distributionMultiple skinfold thicknessesRelative fat massMass indexFat distributionOverall body massSkinfold thicknessBody compositionStudy centersGold standardHip girthStrongest predictorUnderwater weighing