2023
Long-term exposure to ambient air pollution and inflammatory response in the KORA study
Vogli M, Peters A, Wolf K, Thorand B, Herder C, Koenig W, Cyrys J, Maestri E, Marmiroli N, Karrasch S, Zhang S, Pickford R. Long-term exposure to ambient air pollution and inflammatory response in the KORA study. The Science Of The Total Environment 2023, 912: 169416. PMID: 38123091, DOI: 10.1016/j.scitotenv.2023.169416.Peer-Reviewed Original ResearchConceptsLong-term exposure to ambient air pollutionLong-term exposure to air pollutionExposure to ambient air pollutionExposure to air pollutionAmbient air pollutionAir pollutionUltrafine particlesParticulate matterIncrease of PM<sLand-use regression modelsAnnual mean concentrationsAtmospheric particulate matterAssociated with increased IL-6Adverse health effectsAssociated with higher concentrationsLand-useMean concentrationsParticipant's home addressPollutionLong-term studiesHealth effectsHigher concentrationsNitrogen oxidesMultiple linear regressionHome addressEffects of Short- And Medium-Term Exposures to Lower Air Temperature on 71 Novel Biomarkers of Subclinical Inflammation: Results from the KORA F4 Study
Ni W, Breitner S, Nikolaou N, Wolf K, Zhang S, Peters A, Herder C, Schneider A. Effects of Short- And Medium-Term Exposures to Lower Air Temperature on 71 Novel Biomarkers of Subclinical Inflammation: Results from the KORA F4 Study. Environmental Science And Technology 2023, 57: 12210-12221. PMID: 37552838, PMCID: PMC10448716, DOI: 10.1021/acs.est.3c00302.Peer-Reviewed Original ResearchConceptsKORA F4 studyBiomarkers of subclinical inflammationHigher risk of chronic diseasesF4 studyLevels of air pollutionLow air temperatureRisk of chronic diseasesPopulation-based KORA F4 studyCross-sectional analysisSubclinical inflammationAdverse health effectsCumulative lagAssociated with higher levelsAir pollutionAir temperatureChronic diseasesNeurotrophin-3Older participantsInterleukin-6Additive modelMedium-term effectsProximity extension assay technologyHealth effectsCardiovascular diseaseHigh risk
2022
Circulating microRNAs as putative mediators in the association between short-term exposure to ambient air pollution and cardiovascular biomarkers
Chen H, Zhang S, Yu B, Xu Y, Rappold A, Diaz-Sanchez D, Samet J, Tong H. Circulating microRNAs as putative mediators in the association between short-term exposure to ambient air pollution and cardiovascular biomarkers. Ecotoxicology And Environmental Safety 2022, 239: 113604. PMID: 35576800, PMCID: PMC9167781, DOI: 10.1016/j.ecoenv.2022.113604.Peer-Reviewed Original ResearchConceptsExposure to ambient air pollutionAmbient air pollutionExposure to air pollutionAir pollutionShort-term exposure to ambient PM<sub>2.5</sub> waExposure to ambient PM<sub>2.5</sub>Short-term exposure to ambient fine particulate matterShort-term exposure to ambient air pollutionAmbient PM<sub>2.5</sub>Exposure to ambient fine particulate matterAmbient fine particulate matterEffects of exposure to air pollutionAir quality monitoring stationsEffects of air pollution exposureFine particulate matterQuality monitoring stationsAir pollutant concentrationsResearch Triangle area of North CarolinaAir pollution exposureTriangle area of North CarolinaBlood lipid biomarkersResearch Triangle areaPollutant concentrationsParticulate matterPollution exposureOmega-3 fatty acids attenuate cardiovascular effects of short-term exposure to ambient air pollution
Chen H, Zhang S, Shen W, Salazar C, Schneider A, Wyatt L, Rappold A, Diaz-Sanchez D, Devlin R, Samet J, Tong H. Omega-3 fatty acids attenuate cardiovascular effects of short-term exposure to ambient air pollution. Particle And Fibre Toxicology 2022, 19: 12. PMID: 35139860, PMCID: PMC8826673, DOI: 10.1186/s12989-022-00451-4.Peer-Reviewed Original ResearchConceptsExposure to PM2.5Air pollutionEffects of exposure to fine particulate matterShort-term exposure to PM2.5National Ambient Air Quality StandardsU.S. National Ambient Air Quality StandardsExposure to fine particulate matterConcentrations of ambient PM2.5Air quality monitoring stationsAmbient Air Quality StandardsFine particulate matterAir pollutant concentrationsAir quality standardsQuality monitoring stationsResearch Triangle area of North CarolinaAmbient air pollutionResultsThe average concentrationTriangle area of North CarolinaResearch Triangle areaAmbient PM2.5Daily PM2.5Pollutant concentrationsParticulate matterPM2.5Monitoring stations
2021
Association between short-term exposure to ambient fine particulate matter and myocardial injury in the CATHGEN cohort
Zhang S, Breitner S, Cascio W, Devlin R, Neas L, Ward-Caviness C, Diaz-Sanchez D, Kraus W, Hauser E, Schwartz J, Peters A, Schneider A. Association between short-term exposure to ambient fine particulate matter and myocardial injury in the CATHGEN cohort. Environmental Pollution 2021, 275: 116663. PMID: 33581627, DOI: 10.1016/j.envpol.2021.116663.Peer-Reviewed Original ResearchMeSH KeywordsBiomarkersCohort StudiesHumansMyocardial InfarctionMyocardiumParticulate MatterTroponin TConceptsFine particulate matterParticulate matterDaily PM<sub>2.5</sub> concentrationsShort-term exposure to ambient fine particulate matterAcute PM<sub>2.5</sub> exposureAssociation of PM<sub>2.5</sub> wiElevated PM<sub>2.5</sub>Exposure to ambient fine particulate matterExposure to fine particulate matterAmbient fine particulate matterParticipant's residential addressCTnT testNeural network-based hybrid modelResidential addressesElevated indicatorsMeasurement of NT-pro-BNPConcentrationMatterMyocardial infarction symptomsDuke University HospitalInfarction symptomsRural areasOdds ratioCoronary eventsInterquartile rangeLongitudinal associations between ambient air pollution and insulin sensitivity: results from the KORA cohort study
Zhang S, Mwiberi S, Pickford R, Breitner S, Huth C, Koenig W, Rathmann W, Herder C, Roden M, Cyrys J, Peters A, Wolf K, Schneider A. Longitudinal associations between ambient air pollution and insulin sensitivity: results from the KORA cohort study. The Lancet Planetary Health 2021, 5: e39-e49. PMID: 33421408, DOI: 10.1016/s2542-5196(20)30275-8.Peer-Reviewed Original ResearchConceptsLong-term air pollution exposureAir pollution exposureAnnual average air pollutant concentrationsAssociation of air pollutionAverage air pollutant concentrationsPollution exposureLongitudinal associationsType 2 diabetesAir pollutant concentrationsLand-use regression modelsAssociated with air pollution exposureExposure to air pollutionCooperative Health ResearchAmbient air pollutionRegression modelsConcentrations of fasting insulinKORA F4German Federal Ministry of EducationHealth researchIQR incrementAir pollutionAnnual rateKORA cohortDevelopment of type 2 diabetesKORA S4