Effects of Short- And Medium-Term Exposures to Lower Air Temperature on 71 Novel Biomarkers of Subclinical Inflammation: Results from the KORA F4 Study
Ni W, Breitner S, Nikolaou N, Wolf K, Zhang S, Peters A, Herder C, Schneider A. Effects of Short- And Medium-Term Exposures to Lower Air Temperature on 71 Novel Biomarkers of Subclinical Inflammation: Results from the KORA F4 Study. Environmental Science And Technology 2023, 57: 12210-12221. PMID: 37552838, PMCID: PMC10448716, DOI: 10.1021/acs.est.3c00302.Peer-Reviewed Original ResearchConceptsKORA F4 studyBiomarkers of subclinical inflammationHigher risk of chronic diseasesF4 studyLevels of air pollutionLow air temperatureRisk of chronic diseasesPopulation-based KORA F4 studyCross-sectional analysisSubclinical inflammationAdverse health effectsCumulative lagAssociated with higher levelsAir pollutionAir temperatureChronic diseasesNeurotrophin-3Older participantsInterleukin-6Additive modelMedium-term effectsProximity extension assay technologyHealth effectsCardiovascular diseaseHigh riskHeat-related cardiorespiratory mortality: Effect modification by air pollution across 482 cities from 24 countries
Rai M, Stafoggia M, de'Donato F, Scortichini M, Zafeiratou S, Vazquez Fernandez L, Zhang S, Katsouyanni K, Samoli E, Rao S, Lavigne E, Guo Y, Kan H, Osorio S, Kyselý J, Urban A, Orru H, Maasikmets M, Jaakkola J, Ryti N, Pascal M, Hashizume M, Fook Sheng Ng C, Alahmad B, Hurtado Diaz M, De la Cruz Valencia C, Nunes B, Madureira J, Scovronick N, Garland R, Kim H, Lee W, Tobias A, Íñiguez C, Forsberg B, Åström C, Maria Vicedo-Cabrera A, Ragettli M, Leon Guo Y, Pan S, Li S, Gasparrini A, Sera F, Masselot P, Schwartz J, Zanobetti A, Bell M, Schneider A, Breitner S. Heat-related cardiorespiratory mortality: Effect modification by air pollution across 482 cities from 24 countries. Environment International 2023, 174: 107825. PMID: 36934570, DOI: 10.1016/j.envint.2023.107825.Peer-Reviewed Original ResearchConceptsAir pollutionRespiratory mortalityWHO air quality guidelinesElevated levels of air pollutionLevels of air pollutionAir quality guidelinesAmbient air pollutionLevel of pollutionCause-specific mortalityCardiovascular mortalityQuality guidelinesDaily death countsPollutant concentrationsCardiorespiratory mortalityPotential interactive effectsPollutionMitigation measuresPromote sustainable developmentMeta-analytic modelEffect modificationInteractive effects of heatSummer temperaturesSummer monthsExposure dataDeath counts