Differences in Prevalence of Symptomatic Zika Virus Infection, by Age and Sex—Puerto Rico, 2016
Lozier MJ, Burke RM, Lopez J, Acevedo V, Amador M, Read JS, Jara A, Waterman SH, Barrera R, Muñoz-Jordan J, Rivera-Garcia B, Sharp TM. Differences in Prevalence of Symptomatic Zika Virus Infection, by Age and Sex—Puerto Rico, 2016. The Journal Of Infectious Diseases 2017, 217: 1678-1689. PMID: 29216376, PMCID: PMC8849542, DOI: 10.1093/infdis/jix630.Peer-Reviewed Original ResearchConceptsZIKV infectionReverse transcription-polymerase chain reactionEnzyme-linked immunosorbent assaySex-dependent differencesSymptomatic infectionFemale sexSymptomatic Zika virus infectionZika virus infectionSymptomatic ZIKV infectionZika virus diseaseTranscription-polymerase chain reactionNonpregnant womenResidents of householdsZIKV diseaseRecent illnessVirus infectionDisease casesDiagnostic testingStudy participantsInfectionImmunosorbent assayConvenience samplePotential mechanismsChain reactionAgeDengue IgG Seropositivity and Zika Viral Load
Read J, Alvarado L, Torres-Velasquez B, Munoz-Jordan J, Beltran M, Capre S, Adams L, Torres-Torres S, Santiago G, Rivera L, Rivera-Sánchez A, Lorenzi O, Sharp T, Garcia-Gubern C, Waterman S. Dengue IgG Seropositivity and Zika Viral Load. Open Forum Infectious Diseases 2017, 4: s301-s302. PMCID: PMC5631870, DOI: 10.1093/ofid/ofx163.695.Peer-Reviewed Original ResearchPrevious DENV infectionSymptomatic ZIKV infectionDENV IgGDENV infectionZIKV infectionSecondary dengue virus infectionIgG-positive specimensProportion of patientsDengue virus infectionYears of ageIllness surveillance systemZIKV PCRIgG seropositivityRT-PCR resultsLinear regression modelingViral loadIgG assaysPrimary infectionVirus infectionInclusion criteriaStudy populationDENVHouse ELISAInfectionMann-Whitney
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