2018
Vitamin D Deficiency Is Associated With Poor Ovarian Stimulation Outcome in PCOS but Not Unexplained Infertility
Butts SF, Seifer DB, Koelper N, Senapati S, Sammel MD, Hoofnagle AN, Kelly A, Krawetz SA, Santoro N, Zhang H, Diamond MP, Legro RS, Network E. Vitamin D Deficiency Is Associated With Poor Ovarian Stimulation Outcome in PCOS but Not Unexplained Infertility. The Journal Of Clinical Endocrinology & Metabolism 2018, 104: 369-378. PMID: 30085176, PMCID: PMC6300410, DOI: 10.1210/jc.2018-00750.Peer-Reviewed Original ResearchConceptsVitamin D deficiencyPolycystic ovary syndromeD deficiencyEarly pregnancy lossOvarian stimulationUnexplained infertilityLive birthsPregnancy lossDiagnosis of PCOSMultiple Intrauterine GestationsOvarian stimulation outcomesRetrospective cohort studyInvestigation of womenBanked seraPPCOS IICohort studyIntrauterine gestationOvary syndromeInfertile womenInfertility diagnosisPregnant subjectsElevated riskImportant treatmentReproductive outcomesTrial data
2016
Fertility-related quality of life from two RCT cohorts with infertility: unexplained infertility and polycystic ovary syndrome
Santoro N, Eisenberg E, Trussell JC, Craig LB, Gracia C, Huang H, Alvero R, Casson P, Christman G, Coutifaris C, Diamond M, Jin S, Legro RS, Robinson RD, Schlaff WD, Zhang H. Fertility-related quality of life from two RCT cohorts with infertility: unexplained infertility and polycystic ovary syndrome. Human Reproduction 2016, 31: 2268-2279. PMID: 27402910, PMCID: PMC5027926, DOI: 10.1093/humrep/dew175.Peer-Reviewed Original ResearchConceptsPolycystic ovary syndromeFertility-related qualityFertiQoL scoresUnexplained infertilityPregnancy outcomesLower QoLOvary syndromeMale partnersInfertility diagnosisQOL surveyFerring PharmaceuticalsWorldwide cohortPolycystic Ovary Syndrome IIWilcoxon rank-sum testingFirst patient enrollmentMultiple Intrauterine GestationsTime of enrollmentPARTICIPANTS/MATERIALSRank-sum testingNational InstitutePopulation-based sampleROLE OF CHANCEKey participant characteristicsLow socioeconomic statusHirsutism score