2023
Type 2 cytokine genes as allergic asthma risk factors after viral bronchiolitis in early childhood
Dong Z, Myklebust Å, Johnsen I, Jartti T, Døllner H, Risnes K, DeWan A. Type 2 cytokine genes as allergic asthma risk factors after viral bronchiolitis in early childhood. Frontiers In Immunology 2023, 13: 1054119. PMID: 36685501, PMCID: PMC9852873, DOI: 10.3389/fimmu.2022.1054119.Peer-Reviewed Original ResearchConceptsAllergic asthmaViral bronchiolitisRisk factorsViral infectionDetailed lung function testsAllergic asthma developmentHistory of bronchiolitisHuman Metapneumovirus InfectionVariable airway obstructionAsthma risk factorsType 2 cytokinesDevelopment of asthmaLung function testsGenetic variantsCohort of childrenSpecific viral infectionsEarly childhoodType 2 cytokine genesSchool agePotential candidate targetAirway obstructionMetapneumovirus infectionMedian ageAsthma developmentFunction testsPaired Indoor and Outdoor Nitrogen Dioxide Associated With Childhood Asthma Outcomes in a Mixed Rural-Urban Setting: A Feasibility Study
Wi C, Gent J, Bublitz J, King K, Ryu E, Sorrentino K, Plano J, McKay L, Porcher J, Wheeler P, Chiarella S, DeWan A, Pollitt K, Sheares B, Leaderer B, Juhn Y. Paired Indoor and Outdoor Nitrogen Dioxide Associated With Childhood Asthma Outcomes in a Mixed Rural-Urban Setting: A Feasibility Study. Journal Of Primary Care & Community Health 2023, 14: 21501319231173813. PMID: 37243352, PMCID: PMC10226331, DOI: 10.1177/21501319231173813.Peer-Reviewed Original ResearchConceptsAsthma control statusControl statusAsthma diaryRural-urban settingOutdoor NOChildhood asthma outcomesProspective cohort studySocioeconomic statusLow socioeconomic statusSmall feasibility studyAsthma exacerbationsOlmsted CountyPersistent asthmaAsthma outcomesCohort studyChildhood asthmaRural-urban communityLarger sample sizeAsthmaStudy periodHealth effectsFeasibility studyWeeksStatusLow threshold
2019
RE: “RACIAL AND ETHNIC DIFFERENCES IN SOCIOECONOMIC POSITION AND RISK OF CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA”
Spector L, DeWan A, Pankratz N, Turcotte L, Yang J, Scheurer M. RE: “RACIAL AND ETHNIC DIFFERENCES IN SOCIOECONOMIC POSITION AND RISK OF CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA”. American Journal Of Epidemiology 2019, 188: 1192-1193. PMID: 30924856, PMCID: PMC10410092, DOI: 10.1093/aje/kwz075.Peer-Reviewed Original Research
2012
Whole-exome sequencing of a pedigree segregating asthma
DeWan AT, Egan KB, Hellenbrand K, Sorrentino K, Pizzoferrato N, Walsh KM, Bracken MB. Whole-exome sequencing of a pedigree segregating asthma. BMC Medical Genomics 2012, 13: 95. PMID: 23046476, PMCID: PMC3563469, DOI: 10.1186/1471-2350-13-95.Peer-Reviewed Original ResearchConceptsNon-asthmatic childrenWhole-exome sequencingAsthma candidate genesAsthmatic childrenAsthmaAsthma associationsAffected motherExome sequencingUnaffected fatherAsthma-susceptibility variantsPrediction scoreUnaffected offspringCommon risk variantsRisk variantsCandidate genesChildrenNonsynonymous variantsAffected offspring
2010
PDE11A associations with asthma: Results of a genome-wide association scan
DeWan AT, Triche EW, Xu X, Hsu LI, Zhao C, Belanger K, Hellenbrand K, Willis-Owen SA, Moffatt M, Cookson WO, Himes BE, Weiss ST, Gauderman WJ, Baurley JW, Gilliland F, Wilk JB, O’Connor G, Strachan DP, Hoh J, Bracken MB. PDE11A associations with asthma: Results of a genome-wide association scan. Journal Of Allergy And Clinical Immunology 2010, 126: 871-873.e9. PMID: 20920776, PMCID: PMC3133448, DOI: 10.1016/j.jaci.2010.06.051.Peer-Reviewed Original Research
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