2023
Residential proximity to unconventional oil and gas development and birth defects in Ohio
Gaughan C, Sorrentino K, Liew Z, Johnson N, Clark C, Soriano M, Plano J, Plata D, Saiers J, Deziel N. Residential proximity to unconventional oil and gas development and birth defects in Ohio. Environmental Research 2023, 229: 115937. PMID: 37076028, PMCID: PMC10198955, DOI: 10.1016/j.envres.2023.115937.Peer-Reviewed Original ResearchConceptsNeural tube defectsCertain birth defectsBirth defectsOdds ratioRegistry-based cohort studyTube defectsConfidence intervalsResidential proximityState birth recordsBirth defect typeState surveillance systemsMaternal residential proximityLimb reduction defectsCohort studyUnexposed mothersStructural birth defectsLive birthsInfant sexBirth recordsSpina bifidaReduction defectsFemale offspringDevelopmental toxicantsExposure metrics
2014
Asthma medication use during pregnancy, wheeze and estimated exposure to ambient nitrogen dioxide
Gent JF, Kezik JM, Hill ME, McKay LA, Holford TR, Leaderer BP, Bracken MB. Asthma medication use during pregnancy, wheeze and estimated exposure to ambient nitrogen dioxide. European Respiratory Journal 2014, 45: 538-540. PMID: 25537555, PMCID: PMC4331059, DOI: 10.1183/09031936.00161514.Peer-Reviewed Original ResearchConceptsAsthma medication useMedication usePregnant womenRisk of wheezePoor pulmonary functionAdverse health outcomesPregnant asthmaticsAsthma exacerbationsAsthma medicationsPerinatal complicationsPulmonary functionFetal growthHealth outcomesPregnancyNO2 exposureWheezeAsthmaMedicationsWomenAmbient nitrogen dioxideMothersMinimal effectExposureAsthmaticsExacerbation
2013
Household Levels of Nitrogen Dioxide and Pediatric Asthma Severity
Belanger K, Holford TR, Gent JF, Hill ME, Kezik JM, Leaderer BP. Household Levels of Nitrogen Dioxide and Pediatric Asthma Severity. Epidemiology 2013, 24: 320-330. PMID: 23337243, PMCID: PMC3686297, DOI: 10.1097/ede.0b013e318280e2ac.Peer-Reviewed Original ResearchConceptsAsthma severityNight symptomsAsthma morbiditySeverity scoreNO2 exposureHigher asthma severity scoresFrequency of wheezeIndoor NO2 exposurePediatric asthma severityRescue medication useIndoor allergen exposureAsthma severity scoreAdverse respiratory effectsDose-dependent increaseYears of ageInner-city childrenLogistic regression modelsRescue medicationActive asthmaAllergen exposureAsthmatic childrenMedication useRespiratory effectsChildren 5Health outcomes
2012
Household mold and dust allergens: Exposure, sensitization and childhood asthma morbidity
Gent JF, Kezik JM, Hill ME, Tsai E, Li DW, Leaderer BP. Household mold and dust allergens: Exposure, sensitization and childhood asthma morbidity. Environmental Research 2012, 118: 86-93. PMID: 22863552, PMCID: PMC3604733, DOI: 10.1016/j.envres.2012.07.005.Peer-Reviewed Original ResearchConceptsRisk of wheezeSpecific allergen sensitizationRescue medication useChildhood asthma morbidityAsthma severity scoreMedication useAllergen sensitizationPersistent coughAsthma morbiditySeverity scoreHigher asthma severity scoresCommon household allergensCommon indoor allergensFel d 1Der p 1Asthma exacerbationsAllergen exposureLevel of exposureAsthmatic childrenDer pAllergy testingIndoor allergensSchool-aged childrenPet allergensDust allergens