2015
Gene Expression Evolves under a House-of-Cards Model of Stabilizing Selection
Hodgins-Davis A, Rice DP, Townsend JP. Gene Expression Evolves under a House-of-Cards Model of Stabilizing Selection. Molecular Biology And Evolution 2015, 32: 2130-2140. PMID: 25901014, PMCID: PMC4592357, DOI: 10.1093/molbev/msv094.Peer-Reviewed Original ResearchConceptsGene expression evolvesGene expressionPhenotypic evolutionGenetic architectureExpression evolvesEvolutionary quantitative genetic modelsMutation accumulation linesNatural genetic variationStrength of selectionGenomic mutation rateQuantitative genetic modelGenomic data setsGene expression levelsEffects of selectionEvolutionary timeRegulatory evolutionStabilizing selectionAccumulation linesGene regulationMost genesNatural selectionGenetic variationMutational effectsFruit flyPhenotype space
2009
Evolving gene expression: from G to E to G×E
Hodgins-Davis A, Townsend JP. Evolving gene expression: from G to E to G×E. Trends In Ecology & Evolution 2009, 24: 649-658. PMID: 19699549, PMCID: PMC2805859, DOI: 10.1016/j.tree.2009.06.011.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsGene expressionMode of evolutionGene expression data setsTerms of geneticsExpression data setsGenetic variationBreadth of conclusionsEnvironmental responsesGxE interactionsMultiple individualsGeneticsExpressionSingle strainEnvironmental controlEvolutionEnvironmental effectsKey componentSpeciesG×EInteractionStrains
2007
Quantifying variation in gene expression
CLARK TA, TOWNSEND JP. Quantifying variation in gene expression. Molecular Ecology 2007, 16: 2613-2616. PMID: 17594433, DOI: 10.1111/j.1365-294x.2007.03354.x.Commentaries, Editorials and Letters
2005
Designing Experiments Using Spotted Microarrays to Detect Gene Regulation Differences Within and Among Species
Townsend JP, Taylor JW. Designing Experiments Using Spotted Microarrays to Detect Gene Regulation Differences Within and Among Species. Methods In Enzymology 2005, 395: 597-617. PMID: 15865986, DOI: 10.1016/s0076-6879(05)95031-3.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsDNA, ComplementaryGene Expression RegulationNucleic Acid HybridizationOligonucleotide Array Sequence AnalysisRNA, MessengerSpecies SpecificityConceptsGene expressionGenome-wide gene expressionGene regulation differencesDifferential gene expressionMultiple developmental stagesMultiple environmental conditionsMultiple speciesDevelopmental stagesRegulation differencesSpeciesEnvironmental conditionsMultiple individualsMicroarrayExpressionSuch studiesStatistical powerExperimental protocol