2017
Distributions of Mutational Effects and the Estimation of Directional Selection in Divergent Lineages of Arabidopsis thaliana
Park B, Rutter MT, Fenster CB, Symonds VV, Ungerer MC, Townsend JP. Distributions of Mutational Effects and the Estimation of Directional Selection in Divergent Lineages of Arabidopsis thaliana. Genetics 2017, 206: 2105-2117. PMID: 28550014, PMCID: PMC5560809, DOI: 10.1534/genetics.116.199190.Peer-Reviewed Original ResearchMeSH KeywordsArabidopsisEvolution, MolecularModels, GeneticMutation AccumulationQuantitative Trait LociSelection, GeneticConceptsMutation accumulation dataDirectional selectionNatural selectionMutational effectsPhenotypic traitsDirectional natural selectionQuantitative trait lociDivergent lineagesRosette diameterTrait lociHistorical selectionQuantitative traitsLineagesArabidopsisTraitsDensity traitsAccumulation dataDivergenceKey roleUltimate sourceLociSelectionOrganismsKey componentMutations
2012
Resampling QTL Effects in the QTL Sign Test Leads to Incongruous Sensitivity to Variance in Effect Size
Rice DP, Townsend JP. Resampling QTL Effects in the QTL Sign Test Leads to Incongruous Sensitivity to Variance in Effect Size. G3: Genes, Genomes, Genetics 2012, 2: 905-911. PMID: 22908039, PMCID: PMC3411246, DOI: 10.1534/g3.112.003228.Peer-Reviewed Original ResearchMeSH KeywordsAllelesModels, GeneticPhenotypeQuantitative Trait LociQuantitative Trait, HeritableSelection, GeneticA Test for Selection Employing Quantitative Trait Locus and Mutation Accumulation Data
Rice DP, Townsend JP. A Test for Selection Employing Quantitative Trait Locus and Mutation Accumulation Data. Genetics 2012, 190: 1533-1545. PMID: 22298701, PMCID: PMC3316662, DOI: 10.1534/genetics.111.137075.Peer-Reviewed Original ResearchConceptsMutation accumulation dataPhenotypic traitsMutational effectsMutation accumulation experimentsPopulation genetics theoryQuantitative trait lociQuantitative phenotypic traitsAccumulation dataHistory of selectionLocus effect sizesEvolutionary biologistsNeutral evolutionGenetic architectureQTL dataStrong selectionTrait lociSelection strengthDistribution of mutationsNatural selectionPhenotypic diversityHistorical selectionMolecular dataQuantitative traitsGenetic theoryQTL