2011
SIR2 and other genes are abundantly expressed in long-lived natural segregants for replicative aging of the budding yeast Saccharomyces cerevisiae
Guo Z, Adomas AB, Jackson ED, Qin H, Townsend JP. SIR2 and other genes are abundantly expressed in long-lived natural segregants for replicative aging of the budding yeast Saccharomyces cerevisiae. FEMS Yeast Research 2011, 11: 345-355. PMID: 21306556, DOI: 10.1111/j.1567-1364.2011.00723.x.Peer-Reviewed Original ResearchMeSH KeywordsCell CycleCell ProliferationGene Expression ProfilingGene Expression Regulation, FungalGenes, FungalHSP30 Heat-Shock ProteinsHydrogen PeroxideMicrobial ViabilityMitochondrial Membrane Transport ProteinsMitochondrial Precursor Protein Import Complex ProteinsOligonucleotide Array Sequence AnalysisPhenotypePolymerase Chain ReactionSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSilent Information Regulator Proteins, Saccharomyces cerevisiaeSirtuin 2Up-RegulationConceptsReplicative agingWhole genome gene expressionNatural S. cerevisiaeExpression levelsLife span variationDifferential expression levelsDifferent expression levelsEffects of genesNatural populationsYeast SaccharomycesOrganelle organizationS. cerevisiaeGene expressionNatural variationCell cycleStress responseSir2Mitochondrial functionGenesSaccharomycesAllelic associationSpan variationProgenyMetabolic responseTim17
2006
Population structure and gene evolution in Saccharomyces cerevisiae
Aa E, Townsend JP, Adams RI, Nielsen KM, Taylor JW. Population structure and gene evolution in Saccharomyces cerevisiae. FEMS Yeast Research 2006, 6: 702-715. PMID: 16879422, DOI: 10.1111/j.1567-1364.2006.00059.x.Peer-Reviewed Original ResearchConceptsPopulation genetic variationPopulation structureS. cerevisiaeDistinct population structureSaccharomyces sensu strictoSulfur-based fungicidesSulfite exporterGene evolutionGene treesGene SSU1Historical selectionTranscription factorsHigh polymorphismNatural isolatesProtein productsCerevisiaeSequence analysisSSU1Oak forestsGreater polymorphismSensu strictoWine yeastSequence studiesFZF1Expression levelsEcological and evolutionary genomics of Saccharomyces cerevisiae
LANDRY CR, TOWNSEND JP, HARTL DL, CAVALIERI D. Ecological and evolutionary genomics of Saccharomyces cerevisiae. Molecular Ecology 2006, 15: 575-591. PMID: 16499686, DOI: 10.1111/j.1365-294x.2006.02778.x.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsEvolutionary genomic studiesPrime model systemImportant genetic variationPowerful model speciesEvolutionary genomicsEvolutionary geneticsEvolutionary forcesFunctional genomicsYeast genomeNumerous habitatsModel speciesGenomic studiesUnicellular fungiGenetic variationBiology questionsS. cerevisiaeNatural isolatesGenetic levelGenomicsSaccharomycesModel systemYeastEukaryotesGenomeHabitats
2003
Population Genetic Variation in Genome-Wide Gene Expression
Townsend JP, Cavalieri D, Hartl DL. Population Genetic Variation in Genome-Wide Gene Expression. Molecular Biology And Evolution 2003, 20: 955-963. PMID: 12716989, DOI: 10.1093/molbev/msg106.Peer-Reviewed Original ResearchConceptsGene expression levelsGene expressionNatural populationsGenetic variationNatural isolatesExpression levelsGenome-wide gene expressionPopulation genetic variationGenome-wide scaleComparative gene expressionDifferential gene expressionDNA microarray technologyAmino acid metabolismWine yeast SaccharomycesSulfur assimilationEvolutionary biologistsGenomic scaleYeast SaccharomycesNatural selectionS. cerevisiaeProtein degradationSuch traitsDifferential reproductionMicroarray technologyOrganic evolution
2000
Manifold anomalies in gene expression in a vineyard isolate of Saccharomyces cerevisiae revealed by DNA microarray analysis
Cavalieri D, Townsend J, Hartl D. Manifold anomalies in gene expression in a vineyard isolate of Saccharomyces cerevisiae revealed by DNA microarray analysis. Proceedings Of The National Academy Of Sciences Of The United States Of America 2000, 97: 12369-12374. PMID: 11035792, PMCID: PMC17348, DOI: 10.1073/pnas.210395297.Peer-Reviewed Original ResearchConceptsDNA microarray analysisGene expressionNatural populationsSaccharomyces cerevisiaeMicroarray analysisGenome-wide transcriptional profilingAmino acid permeasesAmino acid biosynthesisSuite of traitsGlobal expression analysisSmooth colony phenotypeExtent of heterozygosityGlobal patternsVineyard isolateGene functionEvolutionary biologyNitrogen assimilationAcid biosynthesisSingle geneTranscriptional profilingUnlinked lociColony phenotypeHomothallic strainsS. cerevisiaeDiploid progeny