2008
Sleuthing the difference a nucleotide can make
Townsend JP. Sleuthing the difference a nucleotide can make. Molecular Ecology 2008, 17: 2793-2795. PMID: 18565029, DOI: 10.1111/j.1365-294x.2008.03824.x.Peer-Reviewed Original ResearchConceptsGene expression polymorphismsExpression polymorphismsGenetic variationGene expressionGenome-wide gene expressionPotential evolutionary impactCis-regulatory regionsAmino acid sensorsDifferential gene expressionSingle nucleotide insertionEcological genomicsEvolutionary impactNatural populationsDifferential fitnessYeast SaccharomycesTranscription factorsGenetic basisNatural isolatesHomonucleotide repeatsNatural variationNucleotide insertionEnvironment interactionPolymorphismAcid sensorsSSY1
2000
Solvent Accessibility and Purifying Selection Within Proteins of Escherichia coli and Salmonella enterica
Bustamante CD, Townsend JP, Hartl DL. Solvent Accessibility and Purifying Selection Within Proteins of Escherichia coli and Salmonella enterica. Molecular Biology And Evolution 2000, 17: 301-308. PMID: 10677853, DOI: 10.1093/oxfordjournals.molbev.a026310.Peer-Reviewed Original ResearchConceptsSecondary structure elementsSolvent accessibilityEscherichia coliAmino acid sizeAmino acid polymorphismsSalmonella entericaPurifying selectionMolecular evolutionNeutral theoryProtein foldingPolymorphic sequence variationsSynonymous polymorphismSequence variationProtein structureAcid polymorphismsSecondary structureAmino acidsAcid sizePolymorphismProteinColiEntericaObserved variationSelectionFolding