2019
Modelling microbial infection to address global health challenges
Fitzpatrick MC, Bauch CT, Townsend JP, Galvani AP. Modelling microbial infection to address global health challenges. Nature Microbiology 2019, 4: 1612-1619. PMID: 31541212, PMCID: PMC6800015, DOI: 10.1038/s41564-019-0565-8.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsOptimization of modelsGlobal health challengeDisease transmission dynamicsHealth challengesEpidemiological modellingAccuracy of predictionDifferent intervention strategiesPandemic preparednessInfectious diseasesTransmission dynamicsMicrobial infectionsIntervention strategiesModel developmentPublic healthDiseaseHIV crisisModelOptimizationRiskHealthDynamicsModellingClose collaborationMethodological advancesModelers
2012
Controlling Antimicrobial Resistance through Targeted, Vaccine-Induced Replacement of Strains
Tekle YI, Nielsen KM, Liu J, Pettigrew MM, Meyers LA, Galvani AP, Townsend JP. Controlling Antimicrobial Resistance through Targeted, Vaccine-Induced Replacement of Strains. PLOS ONE 2012, 7: e50688. PMID: 23227198, PMCID: PMC3515573, DOI: 10.1371/journal.pone.0050688.Peer-Reviewed Original ResearchConceptsFirst clinical interventionImportant public health toolPan-resistant strainsInsufficient immune responsePublic health toolMulti-resistant strainsStaphylococcus aureus genotypesVaccine efficacyNosocomial outbreaksDrug treatmentImmune responseResistant serotypesFrequent reasonHypothetical vaccineVaccine developmentStrain replacementVaccineInfectious diseasesAureus genotypesClinical interventionsInfectionHealth toolsAntimicrobial resistanceIntervention strategiesSerotypes