2018
The Cancer Tree
Townsend JP. The Cancer Tree. Scientific American 2018, 318: 34-41. PMID: 29557973, DOI: 10.1038/scientificamerican0418-34.Publications for non-academic audiencesEvolutionary studiesGenetic changes
2016
Early and multiple origins of metastatic lineages within primary tumors
Zhao ZM, Zhao B, Bai Y, Iamarino A, Gaffney SG, Schlessinger J, Lifton RP, Rimm DL, Townsend JP. Early and multiple origins of metastatic lineages within primary tumors. Proceedings Of The National Academy Of Sciences Of The United States Of America 2016, 113: 2140-2145. PMID: 26858460, PMCID: PMC4776530, DOI: 10.1073/pnas.1525677113.Peer-Reviewed Original ResearchConceptsMetastatic lineagesGenetic changesEarly genetic divergenceMolecular evolutionary modelsSingle genetic changeDivergent lineagesTumor phylogeneticsDivergence timesAncestral stateGenetic divergenceCancer lineagesPhylogenetic analysisEvolutionary processesLineagesCancer evolutionMultiple originsDriver genesCancer biologyCancer progressionSomatic mutationsTumor developmentEvolutionary modelsDriver mutationsChronogramMutations
2006
Eukaryotic microbes, species recognition and the geographic limits of species: examples from the kingdom Fungi
Taylor JW, Turner E, Townsend JP, Dettman JR, Jacobson D. Eukaryotic microbes, species recognition and the geographic limits of species: examples from the kingdom Fungi. Philosophical Transactions Of The Royal Society B Biological Sciences 2006, 361: 1947-1963. PMID: 17062413, PMCID: PMC1764934, DOI: 10.1098/rstb.2006.1923.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsGlobal geographic rangeGeographic rangeSpecies recognitionFungal speciesGenetic isolationEukaryotic microbesSmall organismsNon-exclusive reasonsPhylogenetic species recognitionEndemic speciesRecognizable morphological changesEukaryotic speciesMorphological changesPhylogenetic speciesGeographic limitsReproductive isolationMorphological speciesKingdom FungiMorphological charactersMicrobial organismsGenetic changesSpeciesMorphological differencesOrganismsFungi