2012
Assessing the Probability of Detection of Horizontal Gene Transfer Events in Bacterial Populations
Townsend JP, Bøhn T, Nielsen KM. Assessing the Probability of Detection of Horizontal Gene Transfer Events in Bacterial Populations. Frontiers In Microbiology 2012, 3: 27. PMID: 22363321, PMCID: PMC3282476, DOI: 10.3389/fmicb.2012.00027.Peer-Reviewed Original ResearchHorizontal gene transfer eventsGene transfer eventsHGT eventsBacterial populationsPopulation genetics theoryTransfer eventsPopulation genetic modelingLevels of selectionBacterial generation timesGenetic driftNatural selectionInitial transformantsGenetic theoryExogenous DNAAntibiotic resistance genesGenetic materialResistance genesStructured populationsImmediate offspringBacterial genotypesGeneration timeHGTBacteriaDNAGrowth dynamics
2004
Monitoring and modeling horizontal gene transfer
Nielsen KM, Townsend JP. Monitoring and modeling horizontal gene transfer. Nature Biotechnology 2004, 22: 1110-1114. PMID: 15340481, DOI: 10.1038/nbt1006.Peer-Reviewed Original ResearchConceptsHorizontal gene transfer eventsPopulation genetic approachesGene transfer eventsStrength of selectionHorizontal gene transferPopulation genetic modelsWild-type bacteriaLarge bacterial populationsHGT hypothesisBacterial generation timesHGT eventsTransgenic plantsGenetic approachesBacterial communitiesBacterial transformantsBacterial populationsPopulation sizeCurrent monitoring effortsGene transferTransfer eventsYears of growthGeneration timeGenetic modelsBacteriaTime of sampling