2008
Associations of Insulin-Like Growth Factor (IGF)—I and IGF-Binding Protein—3 with HIV Disease Progression in Women
Strickler H, Fazzari M, Kovacs A, Isasi C, Napolitano L, Minkoff H, Gange S, Young M, Sharp G, Kaplan R, Cohen M, Gunter M, Harris T, Yu H, Schoenbaum E, Landay A, Anastos K. Associations of Insulin-Like Growth Factor (IGF)—I and IGF-Binding Protein—3 with HIV Disease Progression in Women. The Journal Of Infectious Diseases 2008, 197: 319-327. PMID: 18177247, PMCID: PMC3127259, DOI: 10.1086/524848.Peer-Reviewed Original ResearchConceptsHIV disease progressionT-cell count declineCell count declineDisease progressionIGFBP-3Count declineIGF axisHuman immunodeficiency virus (HIV) disease progressionInsulin-like growth factor (IGF) axisHigher IGFBP-3 levelsIGF-Binding Protein-3Low IGF-I levelsInsulin-like growth factorIGFBP-3 levelsUse of HAARTBaseline serum samplesIGF-I levelsIGF-binding proteinsGrowth factor axisHIV pathogenesisLymphocyte numbersSerum levelsThymic growthImmunodeficiency syndromeMultivariable model
2002
Plasma concentrations of insulin-like growth factors among healthy adult men and postmenopausal women: associations with body composition, lifestyle, and reproductive factors.
Chang S, Wu X, Yu H, Spitz M. Plasma concentrations of insulin-like growth factors among healthy adult men and postmenopausal women: associations with body composition, lifestyle, and reproductive factors. Cancer Epidemiology Biomarkers & Prevention 2002, 11: 758-66. PMID: 12163330.Peer-Reviewed Original ResearchConceptsInsulin-like growth factorIGF BP-3 levelsBody mass indexBP-3 levelsIGF BP-3IGF-II levelsHormone replacement therapyIGF-I levelsLow physical activityIGF levelsIGF-IIPhysical activityPostmenopausal womenHRT useCaloric intakeReproductive factorsLower IGF-II levelsTraditional cancer risk factorsLow IGF-I levelsPlasma insulin-like growth factorHigher body mass indexGrowth factorIGF-BP levelsPlasma IGF-IIRecent HRT use