2006
DOPA decarboxylase gene is associated with nicotine dependence
Zhang H, Ye Y, Wang X, Gelernter J, Z J, Li MD. DOPA decarboxylase gene is associated with nicotine dependence. Pharmacogenomics 2006, 7: 1159-1166. PMID: 17184203, DOI: 10.2217/14622416.7.8.1159.Peer-Reviewed Original ResearchDetection of Genes for Ordinal Traits in Nuclear Families and a Unified Approach for Association Studies
Zhang H, Wang X, Ye Y. Detection of Genes for Ordinal Traits in Nuclear Families and a Unified Approach for Association Studies. Genetics 2006, 172: 693-699. PMID: 16219774, PMCID: PMC1456175, DOI: 10.1534/genetics.105.049122.Peer-Reviewed Original ResearchConceptsSingle nucleotide polymorphismsQuantitative traitsOrdinal traitsTraditional linkage studiesGenomewide association analysisAssociation of genesDetection of genesGametic disequilibriumLoci existAssociation studiesAssociation analysisGenesLinkage disequilibriumTraitsComplex diseasesLinkage studiesGrowth-associated protein 43Protein 43DisequilibriumPolymorphismFamilyMarkersNuclear families
2002
Genomewide Scan of Hoarding in Sib Pairs in Which Both Sibs Have Gilles de la Tourette Syndrome
Zhang H, Leckman JF, Pauls DL, Tsai CP, Kidd KK, Campos MR, Genetics T. Genomewide Scan of Hoarding in Sib Pairs in Which Both Sibs Have Gilles de la Tourette Syndrome. American Journal Of Human Genetics 2002, 70: 896-904. PMID: 11840360, PMCID: PMC379118, DOI: 10.1086/339520.Peer-Reviewed Original ResearchAllelesBehavioral SymptomsChromosomes, HumanChromosomes, Human, Pair 17Chromosomes, Human, Pair 4Chromosomes, Human, Pair 5Gene FrequencyGenetic LinkageGenetic MarkersGenome, HumanHumansMatched-Pair AnalysisNuclear FamilyObsessive-Compulsive DisorderPhenotypeQuantitative Trait, HeritableSoftwareStatistics, NonparametricTourette Syndrome
1997
Cost-effective sib-pair designs in the mapping of quantitative-trait loci.
Zhao H, Zhang H, Rotter JI. Cost-effective sib-pair designs in the mapping of quantitative-trait loci. American Journal Of Human Genetics 1997, 60: 1211-21. PMID: 9150169, PMCID: PMC1712450.Peer-Reviewed Original Research
1996
Mapping quantitative trait loci with extreme discordant sib pairs: sampling considerations.
Risch N, Zhang H. Mapping quantitative trait loci with extreme discordant sib pairs: sampling considerations. American Journal Of Human Genetics 1996, 58: 836-43. PMID: 8644748, PMCID: PMC1914664.Peer-Reviewed Original Research
1995
Extreme Discordant Sib Pairs for Mapping Quantitative Trait Loci in Humans
Risch N, Zhang H. Extreme Discordant Sib Pairs for Mapping Quantitative Trait Loci in Humans. Science 1995, 268: 1584-1589. PMID: 7777857, DOI: 10.1126/science.7777857.Peer-Reviewed Original Research