Soluble levels of CD27 and CD30 are associated with risk of non‐Hodgkin lymphoma in three Chinese prospective cohorts
Bassig BA, Shu XO, Koh WP, Gao YT, Purdue MP, Butler LM, Adams-Haduch J, Xiang YB, Kemp TJ, Wang R, Pinto LA, Zheng T, Ji BT, Hosgood HD, Hu W, Yang G, Zhang H, Chow WH, Kim C, Seow WJ, Zheng W, Yuan JM, Lan Q, Rothman N. Soluble levels of CD27 and CD30 are associated with risk of non‐Hodgkin lymphoma in three Chinese prospective cohorts. International Journal Of Cancer 2015, 137: 2688-2695. PMID: 26095604, PMCID: PMC4898881, DOI: 10.1002/ijc.29637.Peer-Reviewed Original ResearchConceptsNon-Hodgkin lymphomaB cell activationProspective studyNHL riskWestern populationsChinese prospective cohortIntermediate endpoint biomarkersCase-control studySoluble CD30Prospective cohortSoluble CD27Fourth quartileBlood drawLowest quartileEndpoint biomarkersNHL casesImportant underlying mechanismChinese menSimilar associationSoluble levelsSCD27SCD30CD30CD27Underlying mechanismOccupational Exposure to Benzene and Non-Hodgkin Lymphoma in a Population-Based Cohort: The Shanghai Women’s Health Study
Bassig BA, Friesen MC, Vermeulen R, Shu XO, Purdue MP, Stewart PA, Xiang YB, Chow WH, Zheng T, Ji BT, Yang G, Linet MS, Hu W, Zhang H, Zheng W, Gao YT, Rothman N, Lan Q. Occupational Exposure to Benzene and Non-Hodgkin Lymphoma in a Population-Based Cohort: The Shanghai Women’s Health Study. Environmental Health Perspectives 2015, 123: 971-977. PMID: 25748391, PMCID: PMC4590744, DOI: 10.1289/ehp.1408307.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBenzeneChinaFemaleHumansLymphoma, Non-HodgkinMiddle AgedOccupational DiseasesOccupational ExposureProspective StudiesRisk AssessmentWomen's HealthConceptsNon-Hodgkin lymphomaShanghai Women's Health StudyWomen's Health StudyBenzene exposureHealth StudyNHL riskOccupational exposurePopulation-based prospective cohortCox proportional hazards modelInconsistent epidemiologic evidenceCancer Working GroupProportional hazards modelOccupational benzene exposureCumulative exposure levelsExposure tertilesUnexposed womenProspective cohortEpidemiologic evidenceHigh riskOccupational historyHazards modelExposure levelsWomenHigh associationExposure metrics