2019
Human chromatin remodeler cofactor, RNA interactor, eraser and writer sperm RNAs responding to obesity
Swanson GM, Estill M, Diamond MP, Legro RS, Coutifaris C, Barnhart KT, Huang H, Hansen KR, Trussell JC, Coward RM, Zhang H, Goodrich R, Krawetz SA. Human chromatin remodeler cofactor, RNA interactor, eraser and writer sperm RNAs responding to obesity. Epigenetics 2019, 15: 32-46. PMID: 31354029, PMCID: PMC6961666, DOI: 10.1080/15592294.2019.1644880.Peer-Reviewed Original ResearchConceptsSperm RNASperm DNA methylationChromosome organizationCoregulatory networkGene OntologyDNA methylationResponse pathwaysCellular stressRNA elementsRNAInteractorsErasersCofactorOvarian stimulation (AMIGOS) trialMethylationObesity-related inflammationTranscriptsMeasures of obesityAdipogenesisPathwayMultiple gestationsStimulation trialsAnimal modelsBMIHuman studies
2015
Male obesity is an independent risk factor for treatment failure among couples with unexplained infertility in the assessment of multiple intrauterine gestations from ovarian stimulation (AMIGOS) trial
Polotsky A, Allshouse A, Krawetz S, Santoro N, Eisenberg E, Zhang H, Diamond M. Male obesity is an independent risk factor for treatment failure among couples with unexplained infertility in the assessment of multiple intrauterine gestations from ovarian stimulation (AMIGOS) trial. Fertility And Sterility 2015, 104: e78. DOI: 10.1016/j.fertnstert.2015.07.238.Peer-Reviewed Original ResearchAssessment of multiple intrauterine gestations from ovarian stimulation (AMIGOS) trial: baseline characteristics
Diamond MP, Legro RS, Coutifaris C, Alvero R, Robinson RD, Casson P, Christman GM, Ager J, Huang H, Hansen KR, Baker V, Usadi R, Seungdamrong A, Bates GW, Rosen RM, Haisonleder D, Krawetz SA, Barnhart K, Trussell JC, Jin Y, Santoro N, Eisenberg E, Zhang H, Network I. Assessment of multiple intrauterine gestations from ovarian stimulation (AMIGOS) trial: baseline characteristics. Fertility And Sterility 2015, 103: 962-973.e4. PMID: 25707331, PMCID: PMC4529113, DOI: 10.1016/j.fertnstert.2014.12.130.Peer-Reviewed Original ResearchConceptsAntimüllerian hormone levelsAntral follicle countBody mass indexBaseline characteristicsClomiphene citrateOvarian stimulationUnexplained infertilityFollicle countHormone levelsSemen parametersMean body mass indexGood ovarian reserveMultiple Intrauterine GestationsOvarian stimulation (AMIGOS) trialUse of letrozoleComparable patient populationsProspective clinical trialsCause of infertilityOvulation induction medicationsRate of multiplesCommon baseline characteristicsNormal semen parametersBasal FSHInfertility durationBaseline demographics
2011
Estimating rates of multiple gestation pregnancies: Sample size calculation from the assessment of multiple intrauterine gestations from ovarian stimulation (AMIGOS) trial
Diamond MP, Mitwally M, Casper R, Ager J, Legro RS, Brzyski R, Casson P, Eisenberg E, Zhang H, Network F. Estimating rates of multiple gestation pregnancies: Sample size calculation from the assessment of multiple intrauterine gestations from ovarian stimulation (AMIGOS) trial. Contemporary Clinical Trials 2011, 32: 902-908. PMID: 21787883, PMCID: PMC3708642, DOI: 10.1016/j.cct.2011.07.009.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAromatase InhibitorsClomipheneDose-Response Relationship, DrugDouble-Blind MethodFemaleFertility Agents, FemaleGonadotropinsHumansInfant, NewbornInfertilityLetrozoleMaleNitrilesOvulation InductionPregnancyPregnancy OutcomePregnancy, MultipleProspective StudiesTreatment OutcomeTriazolesYoung AdultConceptsMultiple Intrauterine GestationsMultiple gestation pregnanciesOvulation inductionUnexplained infertilityGestation pregnanciesIntrauterine gestationMultiple gestationsComparable pregnancy ratesMono-follicular developmentOvarian stimulation (AMIGOS) trialOvarian hyperstimulation syndromePregnancy success ratePublic health benefitsExpense of careHyperstimulation syndromeClomiphene citrateNeonatal morbidityPreterm laborFertility medicationsPreterm infantsIntrauterine inseminationStimulation trialsAromatase inhibitorsPregnancy rateGestation