2019
Use of aspirin, other nonsteroidal anti-inflammatory drugs and acetaminophen and risk of endometrial cancer: the Epidemiology of Endometrial Cancer Consortium
Webb PM, Na R, Weiderpass E, Adami HO, Anderson KE, Bertrand KA, Botteri E, Brasky TM, Brinton LA, Chen C, Doherty JA, Lu L, McCann SE, Moysich KB, Olson S, Petruzella S, Palmer JR, Prizment AE, Schairer C, Setiawan VW, Spurdle AB, Trabert B, Wentzensen N, Wilkens L, Yang HP, Yu H, Risch HA, Jordan SJ. Use of aspirin, other nonsteroidal anti-inflammatory drugs and acetaminophen and risk of endometrial cancer: the Epidemiology of Endometrial Cancer Consortium. Annals Of Oncology 2019, 30: 310-316. PMID: 30566587, PMCID: PMC6386026, DOI: 10.1093/annonc/mdy541.Peer-Reviewed Original ResearchConceptsNon-aspirin nonsteroidal anti-inflammatory drugsNonsteroidal anti-inflammatory drugsEndometrial Cancer ConsortiumEndometrial cancerAnti-inflammatory drugsObese womenOdds ratioCancer ConsortiumStudy-specific odds ratiosLogistic regressionStandard-dose aspirinUse of aspirinUse of acetaminophenConfidence intervalsTimes/weekCase-control studyRisk of cancerMixed-effects logistic regressionLow-dose formulationsLeast weekly useNormal weightPooled analysisInverse associationStratified analysisReduced risk
2014
Integrative post-genome-wide association analysis of CDKN2A and TP53 SNPs and risk of esophageal adenocarcinoma
Buas MF, Levine DM, Makar KW, Utsugi H, Onstad L, Li X, Galipeau PC, Shaheen NJ, Hardie LJ, Romero Y, Bernstein L, Gammon MD, Casson AG, Bird NC, Risch HA, Ye W, Liu G, Corley DA, Blount PL, Fitzgerald RC, Whiteman DC, Wu AH, Reid BJ, Vaughan TL. Integrative post-genome-wide association analysis of CDKN2A and TP53 SNPs and risk of esophageal adenocarcinoma. Carcinogenesis 2014, 35: 2740-2747. PMID: 25280564, PMCID: PMC4247522, DOI: 10.1093/carcin/bgu207.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAgedBarrett EsophagusCase-Control StudiesCyclin-Dependent Kinase Inhibitor p16Disease ProgressionEsophageal NeoplasmsFemaleFollow-Up StudiesGenome-Wide Association StudyHumansMaleMiddle AgedNeoplasm StagingPolymorphism, Single NucleotidePrognosisRisk FactorsTumor Suppressor Protein p53ConceptsEsophageal adenocarcinomaBarrett's esophagusSingle nucleotide polymorphismsRisk of EACPredictors of progressionGermline single nucleotide polymorphismsTP53 single nucleotide polymorphismsNucleotide polymorphismsCDKN2A polymorphismsEA tumorsFrequent somatic mutationsProspective cohortCDKN2A variantsMale genderRisk factorsReduced riskTumor suppressor gene CDKN2ACaucasian raceMiR-663bEA casesSomatic alterationsGermline variationAdenocarcinomaGenes CDKN2AEsophagusIntrauterine devices and endometrial cancer risk: A pooled analysis of the Epidemiology of Endometrial Cancer Consortium
Felix AS, Gaudet MM, La Vecchia C, Nagle CM, Shu XO, Weiderpass E, Adami HO, Beresford S, Bernstein L, Chen C, Cook LS, De Vivo I, Doherty JA, Friedenreich CM, Gapstur SM, Hill D, Horn‐Ross P, Lacey JV, Levi F, Liang X, Lu L, Magliocco A, McCann SE, Negri E, Olson SH, Palmer JR, Patel AV, Petruzella S, Prescott J, Risch HA, Rosenberg L, Sherman ME, Spurdle AB, Webb PM, Wise LA, Xiang Y, Xu W, Yang HP, Yu H, Zeleniuch‐Jacquotte A, Brinton LA. Intrauterine devices and endometrial cancer risk: A pooled analysis of the Epidemiology of Endometrial Cancer Consortium. International Journal Of Cancer 2014, 136: e410-e422. PMID: 25242594, PMCID: PMC4267918, DOI: 10.1002/ijc.29229.Peer-Reviewed Original ResearchConceptsEndometrial Cancer ConsortiumEndometrial cancer riskIntrauterine deviceEC riskPooled analysisCancer riskLast useCancer ConsortiumOlder ageUse of IUDsMultivariable logistic regressionConfidence intervalsPooled odds ratioCase-control studyInert intrauterine deviceDuration of useHeavy bleedingOdds ratioReversible contraceptivesHormonal changesEC casesReduced riskBiologic effectsUterine environmentLogistic regressionCase–Control Study of Aspirin Use and Risk of Pancreatic Cancer
Streicher SA, Yu H, Lu L, Kidd MS, Risch HA. Case–Control Study of Aspirin Use and Risk of Pancreatic Cancer. Cancer Epidemiology Biomarkers & Prevention 2014, 23: 1254-1263. PMID: 24969230, PMCID: PMC4091763, DOI: 10.1158/1055-9965.epi-13-1284.Peer-Reviewed Original ResearchConceptsAspirin usePancreatic cancerLong-term aspirin useLow-dose aspirinCase-control studyCalendar time periodTime of interviewRisk-benefit analysisAspirin regimenCardiovascular diseaseReduced riskYear of interviewPossible associationCancerConnecticut StudyRegular useAspirinRiskCase frequencySignificant relationshipYearsRegimenComplicationsPrognosisMortality
2012
Green tea drinking and risk of pancreatic cancer: A large-scale, population-based case–control study in urban Shanghai
Wang J, Zhang W, Sun L, Yu H, Ni QX, Risch HA, Gao YT. Green tea drinking and risk of pancreatic cancer: A large-scale, population-based case–control study in urban Shanghai. Cancer Epidemiology 2012, 36: e354-e358. PMID: 22944495, PMCID: PMC3490023, DOI: 10.1016/j.canep.2012.08.004.Peer-Reviewed Original ResearchConceptsPancreatic cancer riskGreen tea drinkingPopulation-based case-control studyCase-control studyPancreatic cancerCancer riskTea drinkingTea consumptionRegular tea drinkingRegular tea drinkersTea drinking habitsUrban ShanghaiHealthy controlsReduced riskEpidemiological studiesTea drinkersRegular drinkingDrinking habitsCancerInterview questionnaireLonger durationTea temperatureWomenDrinkingRiskOmega-3 and omega-6 fatty acid intakes and endometrial cancer risk in a population-based case–control study
Arem H, Neuhouser ML, Irwin ML, Cartmel B, Lu L, Risch H, Mayne ST, Yu H. Omega-3 and omega-6 fatty acid intakes and endometrial cancer risk in a population-based case–control study. European Journal Of Nutrition 2012, 52: 1251-1260. PMID: 22915050, PMCID: PMC3548981, DOI: 10.1007/s00394-012-0436-z.Peer-Reviewed Original ResearchConceptsEndometrial cancer riskFatty acid intakeCancer riskEndometrial cancerAcid intakeDietary intakePopulation-based case-control studyFish oil supplement useUnconditional logistic regression methodsLong-chain omega-3 fatty acidsOmega-3 fatty acidsIncident cancer casesCase-control studyAge-matched controlsFatty acidsPopulation-based sampleTotal fish intakeSupplement useFish intakeExtreme quartilesProtective associationCancer casesHigh intakeReduced riskFatty acids EPA