2024
Doubly robust estimation and sensitivity analysis for marginal structural quantile models
Cheng C, Hu L, Li F. Doubly robust estimation and sensitivity analysis for marginal structural quantile models. Biometrics 2024, 80: ujae045. PMID: 38884127, DOI: 10.1093/biomtc/ujae045.Peer-Reviewed Original ResearchMeSH KeywordsAntihypertensive AgentsBiometryComputer SimulationElectronic Health RecordsHumansHypertensionModels, StatisticalConceptsQuantile modelDistribution of potential outcomesEfficient influence functionPotential outcome distributionsDoubly robust estimatorsTime-varying treatmentsSequential ignorability assumptionSemiparametric frameworkIgnorability assumptionVariance estimationOutcome distributionInfluence functionRobust estimationPotential outcomesEfficient computationFunction approachTime-varying confoundersElectronic health record dataEstimationTreatment assignmentHealth record dataEffect of antihypertensive medicationEquationsRecord dataAntihypertensive medications
2021
Early identification of patients with acute gastrointestinal bleeding using natural language processing and decision rules
Shung D, Tsay C, Laine L, Chang D, Li F, Thomas P, Partridge C, Simonov M, Hsiao A, Tay JK, Taylor A. Early identification of patients with acute gastrointestinal bleeding using natural language processing and decision rules. Journal Of Gastroenterology And Hepatology 2021, 36: 1590-1597. PMID: 33105045, DOI: 10.1111/jgh.15313.Peer-Reviewed Original ResearchConceptsNatural language processingElectronic health recordsLanguage processingNLP algorithmSystematized NomenclatureReal timeAcute gastrointestinal bleedingBidirectional Encoder RepresentationsDecision rulesEHR-based phenotyping algorithmsGastrointestinal bleedingRisk stratification scoresEncoder RepresentationsData elementsPhenotyping algorithmStratification scoresHealth recordsAlgorithmPhenotyping of patientsEmergency department patientsTime of presentationRisk stratification modelED reviewDeploymentExternal validationElectronic health record alerts for acute kidney injury: multicenter, randomized clinical trial
Wilson FP, Martin M, Yamamoto Y, Partridge C, Moreira E, Arora T, Biswas A, Feldman H, Garg AX, Greenberg JH, Hinchcliff M, Latham S, Li F, Lin H, Mansour SG, Moledina DG, Palevsky PM, Parikh CR, Simonov M, Testani J, Ugwuowo U. Electronic health record alerts for acute kidney injury: multicenter, randomized clinical trial. The BMJ 2021, 372: m4786. PMID: 33461986, PMCID: PMC8034420, DOI: 10.1136/bmj.m4786.Peer-Reviewed Original ResearchConceptsAcute kidney injuryElectronic health record alertsKidney injuryPrimary outcomeMedical recordsYale New Haven Health SystemCare practicesGlobal Outcomes creatinine criteriaLarge tertiary care centerComposite of progressionDays of randomizationReceipt of dialysisPrespecified secondary outcomesTertiary care centerPatients' medical recordsSmall community hospitalNon-teaching hospitalsElectronic health recordsCreatinine criteriaUsual careSecondary outcomesAdult inpatientsKidney diseaseClinical centersWorse outcomes