2015
Sugar-sweetened beverage consumption and age at menarche in a prospective study of US girls
Carwile JL, Willett WC, Spiegelman D, Hertzmark E, Rich-Edwards J, Frazier AL, Michels KB. Sugar-sweetened beverage consumption and age at menarche in a prospective study of US girls. Human Reproduction 2015, 30: 675-683. PMID: 25628346, PMCID: PMC4325672, DOI: 10.1093/humrep/deu349.Peer-Reviewed Original ResearchConceptsFrequent SSB consumptionSugar-sweetened beverage consumptionServings of SSBsSSB consumptionEarly menarcheNational InstituteYouth/Adolescent Food Frequency QuestionnaireNurses' Health Study II participantsBeverage consumptionAdolescent Food Frequency QuestionnaireCox proportional hazards regressionBreast Cancer Research FoundationFood frequency questionnaireProspective cohort studyProportional hazards regressionFruit juice consumptionPARTICIPANTS/MATERIALSSugar-sweetened sodaAmerican Cancer SocietyROLE OF CHANCEPublic health effortsCancer Research FoundationNational Cancer InstituteToday StudyUS girls
2005
High school dietary dairy intake and teenage acne
Adebamowo CA, Spiegelman D, Danby FW, Frazier AL, Willett WC, Holmes MD. High school dietary dairy intake and teenage acne. Journal Of The American Academy Of Dermatology 2005, 52: 207-214. PMID: 15692464, DOI: 10.1016/j.jaad.2004.08.007.Peer-Reviewed Original ResearchConceptsTeenage acnePrevalence ratiosNurses' Health Study IIDietary dairy intakeHigh school dietMultivariate prevalence ratiosHealth Study IIBody mass indexCategories of intakeLow-fat milkMass indexSchool dietDairy intakeWestern dietPresence of hormoneAcne historyPossible associationAcneEnergy intakeStudy IIIntakeBreakfast drinksConfidence intervalsTotal milkDairy foods
2004
Reproductive History and Endometriosis Among Premenopausal Women
Missmer SA, Hankinson SE, Spiegelman D, Barbieri RL, Malspeis S, Willett WC, Hunter DJ. Reproductive History and Endometriosis Among Premenopausal Women. Obstetrics And Gynecology 2004, 104: 965-974. PMID: 15516386, DOI: 10.1097/01.aog.0000142714.54857.f8.Peer-Reviewed Original ResearchConceptsHealth Study II cohortParous womenNurses' Health Study II cohortShorter menstrual cyclesProportional hazards modelLifetime durationEarly ageShorter cycle lengthsPast infertilityPremenopausal womenNulliparous womenProspective dataMenstrual cycleReproductive factorsLiveborn childrenHazards modelLast birthEndometriosisGreater incidenceReproductive historyCycle regularityWomenAnatomical changesCalendar timeCycle lengthEarly life menstrual characteristics and pregnancy experiences among women with and without major depression: the Harvard study of moods and cycles
Harlow BL, Cohen LS, Otto MW, Spiegelman D, Cramer DW. Early life menstrual characteristics and pregnancy experiences among women with and without major depression: the Harvard study of moods and cycles. Journal Of Affective Disorders 2004, 79: 167-176. PMID: 15023491, DOI: 10.1016/s0165-0327(02)00459-7.Peer-Reviewed Original ResearchConceptsRisk of depressionMajor depressionHeavy menstrual flowMenstrual cycle characteristicsMonths of breastfeedingNumber of livebirthsYears of menstruationCurrent major depressionHistory of depressionMost risk estimatesPopulation-based sampleYears of ageWomen 36Menstrual characteristicsGynecological careStudy enrollmentDecreased riskMenstrual flowMenstrual cyclePostpartum periodCycle irregularityPsychiatric sequelaePregnancy experiencePremenstrual dysphoriaMultiple abortionsReproductive Factors, Hormonal Contraception, and Risk of Uterine Leiomyomata in African-American Women: A Prospective Study
Wise LA, Palmer JR, Harlow BL, Spiegelman D, Stewart EA, Adams-Campbell LL, Rosenberg L. Reproductive Factors, Hormonal Contraception, and Risk of Uterine Leiomyomata in African-American Women: A Prospective Study. American Journal Of Epidemiology 2004, 159: 113-123. PMID: 14718211, PMCID: PMC1847588, DOI: 10.1093/aje/kwh016.Peer-Reviewed Original ResearchConceptsUS black womenUterine leiomyomataHormonal contraceptionReproductive factorsSelf-reported uterine leiomyomataProspective cohort studyBody mass indexIncidence rate ratiosCox regression modelSelf-reported diagnosisBlack womenAfrican American womenReproductive covariatesCohort studyPremenopausal womenAlcohol intakeMass indexProspective studyInverse associationHormonal factorsLast birthLeiomyomataReproductive historyNew casesFirst birth
1999
Reproducibility of plasma and urinary sex hormone levels in premenopausal women over a one-year period.
Michaud DS, Manson JE, Spiegelman D, Barbieri RL, Sepkovic DW, Bradlow HL, Hankinson SE. Reproducibility of plasma and urinary sex hormone levels in premenopausal women over a one-year period. Cancer Epidemiology Biomarkers & Prevention 1999, 8: 1059-64. PMID: 10613337.Peer-Reviewed Original ResearchConceptsPremenopausal womenIntraclass correlation coefficientLuteal phaseHormone levelsBlood samplesEndogenous sex steroid hormonesUrinary sex hormone levelsUrinary sex hormonesUrinary estrogen metabolitesSex hormone levelsSex steroid hormonesSets of bloodSingle blood sampleHigh intraclass correlation coefficientsLuteal phase samplesPlasma estrogenMenstrual cycleSex hormonesPlasma estradiolBreast cancerEstrogen metabolitesEstrone sulfateUrinary 2One-year periodSteroid hormonesThe relationship between a polymorphism in CYP17 with plasma hormone levels and breast cancer.
Haiman CA, Hankinson SE, Spiegelman D, Colditz GA, Willett WC, Speizer FE, Kelsey KT, Hunter DJ. The relationship between a polymorphism in CYP17 with plasma hormone levels and breast cancer. Cancer Research 1999, 59: 1015-20. PMID: 10070957.Peer-Reviewed Original ResearchConceptsHealth Study cohortBreast cancer riskBreast cancerHormone levelsA2 alleleCancer riskNurses' Health Study cohortStrong independent risk factorA2/A2 genotypeCYP17 A2 alleleElevated levelsAdvanced breast cancerIncident breast cancerIndependent risk factorPolycystic ovarian syndromeCertain steroid hormonesA1/A1 genotypeCase-control studyPlasma hormone levelsSteroid hormone levelsLater agePremenopausal womenCYP17 genotypeHormone replacementOvarian syndrome
1998
Menstrual Cycle Characteristics and History of Ovulatory Infertility in Relation to Breast Cancer Risk in a Large Cohort of US Women
Garland M, Hunter D, Colditz G, Manson J, Stampfer M, Spiegelman D, Speizer F, Willett W. Menstrual Cycle Characteristics and History of Ovulatory Infertility in Relation to Breast Cancer Risk in a Large Cohort of US Women. American Journal Of Epidemiology 1998, 147: 636-643. PMID: 9554602, DOI: 10.1093/oxfordjournals.aje.a009504.Peer-Reviewed Original ResearchConceptsMultivariate relative riskHealth Study IIMenstrual cycle characteristicsBreast cancer riskRelative riskOvulatory infertilityBreast cancerCancer riskLonger menstrual cycle lengthNurses' Health Study IICycle lengthUsual cycle lengthProspective cohort studyMenstrual cycle lengthOvulatory menstrual cyclesCohort studyBaseline questionnaireMenstrual cycleLarge cohortProtective effectUS womenAge 18Study IIInfertilityCycle characteristicsAlcohol and Breast Cancer in Women: A Pooled Analysis of Cohort Studies
Smith-Warner SA, Spiegelman D, Yaun SS, van den Brandt PA, Folsom AR, Goldbohm RA, Graham S, Holmberg L, Howe GR, Marshall JR, Miller AB, Potter JD, Speizer FE, Willett WC, Wolk A, Hunter DJ. Alcohol and Breast Cancer in Women: A Pooled Analysis of Cohort Studies. JAMA 1998, 279: 535-540. PMID: 9480365, DOI: 10.1001/jama.279.7.535.Peer-Reviewed Original ResearchConceptsInvasive breast cancerAlcohol intakeBreast cancerAlcohol consumptionRelative riskIncident invasive breast cancerMultivariate-adjusted relative riskIncident breast cancer casesBeverage-specific alcohol consumptionMultivariate relative riskTotal alcohol intakeFood frequency questionnaireBreast cancer incidenceBreast cancer riskBreast cancer casesRandom-effects modelLong-term intakeCohort studyFrequency questionnaireProspective studyPooled analysisCancer incidenceDiet assessment instrumentsCancer casesNondietary factors