2020
The fidelity of implementation of recommended care for children with malaria by community health workers in Nigeria
Adeoti O, Spiegelman D, Afonne C, Falade CO, Jegede AS, Oshiname FO, Gomes M, Ajayi IO. The fidelity of implementation of recommended care for children with malaria by community health workers in Nigeria. Implementation Science 2020, 15: 13. PMID: 32131852, PMCID: PMC7057616, DOI: 10.1186/s13012-020-0968-1.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntimalarialsArtemisininsCaregiversChild, PreschoolClinical ProtocolsCommunity Health WorkersCounselingDrug Therapy, CombinationEmployee Performance AppraisalFemaleHumansImplementation ScienceInfantInservice TrainingMalariaMicrobiological TechniquesMiddle AgedNigeriaSocioeconomic FactorsConceptsCommunity health workersResource-poor settingsClinical evaluationTreatment protocolHealth workersPerformance scoresFemale community health workersHome-based caregiversMalaria treatment recommendationsUnit increaseGold standard comparatorPost-treatment counselingOverall adherenceTreatment recommendationsMalaria careBetter outcomesQuality careTotal performance scoreFidelity of implementationIntervention fidelityMean performance scoresStandard checklistHome managementMalariaGold standard
2013
Clinical malaria diagnosis in pregnancy in relation to early perinatal mother‐to‐child transmission of HIV: a prospective cohort study
Ezeamama A, Duggan C, Manji K, Spiegelman D, Hertzmark E, Bosch R, Kupka R, Okuma J, Kisenge R, Aboud S, Fawzi W. Clinical malaria diagnosis in pregnancy in relation to early perinatal mother‐to‐child transmission of HIV: a prospective cohort study. HIV Medicine 2013, 15: 276-285. PMID: 24215465, PMCID: PMC4299572, DOI: 10.1111/hiv.12111.Peer-Reviewed Original ResearchConceptsPregnant HIV-positive womenHIV-positive womenRelative riskFever symptomsHIV MTCTHIV infectionPolymerase chain reactionHIV-positive pregnant womenMultivariable logistic regression modelCent of HIVChild's HIV statusHIV MTCT riskInfants of womenPerinatal HIV infectionChild HIV infectionLaboratory-confirmed diagnosisConfidence intervalsPrenatal health careWeeks of lifeLogistic regression modelsHIV motherMaternal malariaMTCT programmeMTCT riskChild transmission
2004
Selenium Status Is Associated with Accelerated HIV Disease Progression among HIV-1–Infected Pregnant Women in Tanzania
Kupka R, Msamanga GI, Spiegelman D, Morris S, Mugusi F, Hunter DJ, Fawzi WW. Selenium Status Is Associated with Accelerated HIV Disease Progression among HIV-1–Infected Pregnant Women in Tanzania. Journal Of Nutrition 2004, 134: 2556-2560. PMID: 15465747, DOI: 10.1093/jn/134.10.2556.Peer-Reviewed Original ResearchConceptsPlasma selenium levelsCD4 cell countRisk of mortalityDisease progressionHIV-1-infected pregnant womenCell countSelenium levelsLow plasma selenium levelsHIV disease progressionAccelerated disease progressionCox multivariate modelSelenium statusMedian followHIV diseaseClinical outcomesPregnant womenPoor survivalTanzanian womenMultivariate modelL increaseCells/ProgressionWomenMortalityFirst year
2002
Vitamin A Supplements Ameliorate the Adverse Effect of HIV-1, Malaria, and Diarrheal Infections on Child Growth
Villamor E, Mbise R, Spiegelman D, Hertzmark E, Fataki M, Peterson KE, Ndossi G, Fawzi WW. Vitamin A Supplements Ameliorate the Adverse Effect of HIV-1, Malaria, and Diarrheal Infections on Child Growth. Pediatrics 2002, 109: e6-e6. PMID: 11773574, DOI: 10.1542/peds.109.1.e6.Peer-Reviewed Original ResearchConceptsMid-upper arm circumferenceMonths of ageVitamin A supplementsPersistent diarrheaHIV infectionRespiratory infectionsVitamin AArm circumferenceHIV statusStudy clinicTreatment armsA supplementsHigher mid-upper arm circumferenceHuman immunodeficiency virus (HIV) infectionInfectious diseasesAdverse effectsLow arm circumferenceEpisodes of infectionImmunodeficiency virus infectionDay of admissionIU vitamin APrevalence of vitaminChild growthConfidence intervalsSeverity of diarrhea
2001
Determinants of low birth weight among HIV-infected pregnant women in Tanzania 1 , 2 , 3
Dreyfuss M, Msamanga G, Spiegelman D, Hunter D, Urassa E, Hertzmark E, Fawzi W. Determinants of low birth weight among HIV-infected pregnant women in Tanzania 1 , 2 , 3. American Journal Of Clinical Nutrition 2001, 74: 814-826. PMID: 11722965, DOI: 10.1093/ajcn/74.6.814.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBirth WeightCohort StudiesDisease ProgressionFemaleHIV InfectionsHumansIncidenceInfant, Low Birth WeightInfant, NewbornInfant, Small for Gestational AgeInfectious Disease Transmission, VerticalLymphocyte CountMalariaMaternal WelfareMiddle AgedOdds RatioParasitic DiseasesPregnancyPregnancy Complications, InfectiousPregnancy OutcomeRandomized Controlled Trials as TopicRisk FactorsTanzaniaConceptsLow birth weightInfant HIV infectionBirth weightHIV infectionMaternal weightRisk factorsIncidence of LBWLow serum vitamin E concentrationsPredictors of LBWCell countAdvanced stage HIV diseaseLower CD8 cell countsMultivariate-adjusted linear regression modelsSerum vitamin E concentrationsInfant risk factorsCD4 cell countCD8 cell countsGestational age statusHIV disease progressionIntestinal parasitic infectionsMean birth weightPlasmodium falciparum malariaHIV-positive womenMidupper arm circumferencePrenatal care clinics
2000
Vitamin A supplementation and other predictors of anemia among children from Dar Es Salaam, Tanzania.
Villamor E, Mbise R, Spiegelman D, Ndossi G, Fawzi WW. Vitamin A supplementation and other predictors of anemia among children from Dar Es Salaam, Tanzania. American Journal Of Tropical Medicine And Hygiene 2000, 62: 590-7. PMID: 11289670, DOI: 10.4269/ajtmh.2000.62.590.Peer-Reviewed Original ResearchConceptsSevere anemiaHemoglobin levelsHuman immunodeficiency virus (HIV) infectionPredictors of anemiaPlacebo-controlled trialImmunodeficiency virus infectionMean hemoglobin levelAssociation of hemoglobinMonths of breastfeedingDiagnosis of malariaYears of agePotential confounding variablesMonth old infantsLow socioeconomic statusHIV infectionIndependent determinantsMalaria infectionMaternal levelsAdditional dosesNonsignificant reductionHematologic profileVirus infectionSignificant fallHemoglobin concentrationVitamin A