2004
Common ataxia telangiectasia mutated haplotypes and risk of breast cancer: a nested case–control study
Tamimi RM, Hankinson SE, Spiegelman D, Kraft P, Colditz GA, Hunter DJ. Common ataxia telangiectasia mutated haplotypes and risk of breast cancer: a nested case–control study. Breast Cancer Research 2004, 6: r416. PMID: 15217510, PMCID: PMC468661, DOI: 10.1186/bcr809.Peer-Reviewed Original ResearchMeSH KeywordsAdultAtaxia TelangiectasiaAtaxia Telangiectasia Mutated ProteinsBreast NeoplasmsCase-Control StudiesCell Cycle ProteinsCohort StudiesDNA-Binding ProteinsFemaleHaplotypesHumansMiddle AgedMutationNursesPolymorphism, Single NucleotideProtein Serine-Threonine KinasesRisk FactorsSurveys and QuestionnairesTumor Suppressor ProteinsConceptsSingle nucleotide polymorphismsATM geneDNA double-strand breaksNucleotide polymorphismsDouble-strand breaksEntire genomic sequenceTumor suppressor geneCommon variationCell cycle arrestHaplotype diversityUnique haplotypesGenomic sequencesAtaxia telangiectasiaSingle nucleotide polymorphism detectionSporadic breast cancer riskSuppressor geneCycle arrestGenesATM haplotypesPolymorphism detectionCommon haplotypeHaplotypesGenotype informationHaplotype analysisMutations
2003
A prospective study of XRCC1 haplotypes and their interaction with plasma carotenoids on breast cancer risk.
Han J, Hankinson SE, De Vivo I, Spiegelman D, Tamimi RM, Mohrenweiser HW, Colditz GA, Hunter DJ. A prospective study of XRCC1 haplotypes and their interaction with plasma carotenoids on breast cancer risk. Cancer Research 2003, 63: 8536-41. PMID: 14679022.Peer-Reviewed Original ResearchConceptsBreast cancer riskBeta-carotene levelsCancer riskInverse associationHealth StudyXRCC1 geneNurses' Health StudyMultivariate odds ratiosCase-control studyPotential protective effectPresent study populationHaplotype-tagging single nucleotide polymorphismsXRCC1 haplotypesCigarette smokingProspective studyCaucasian womenEffect modificationOdds ratioBreast cancerProtective effectStudy populationOxidative DNA damageBreast carcinogenesisGene-environment interactionsPlasma carotenoids