2002
Mercury and the Risk of Coronary Heart Disease in Men
Yoshizawa K, Rimm EB, Morris JS, Spate VL, Hsieh CC, Spiegelman D, Stampfer MJ, Willett WC. Mercury and the Risk of Coronary Heart Disease in Men. New England Journal Of Medicine 2002, 347: 1755-1760. PMID: 12456851, DOI: 10.1056/nejmoa021437.Peer-Reviewed Original ResearchConceptsCoronary heart diseaseHeart diseaseMale health professionalsHigh dietary intakeYears of ageCase-control designMercury levelsSmoking statusTotal mercury exposureControl subjectsLowest quintileRisk factorsDietary intakeCardiovascular diseaseRelative riskCohort membersPrevious historyToenail clippingsHealth professionalsDiseaseConsumption of fishMercury exposureMean mercury levelRiskFish consumption
2001
Prospective study of dietary fat and the risk of age-related macular degeneration 1 , 2 , 3
Cho E, Hung S, Willett W, Spiegelman D, Rimm E, Seddon J, Colditz G, Hankinson S. Prospective study of dietary fat and the risk of age-related macular degeneration 1 , 2 , 3. American Journal Of Clinical Nutrition 2001, 73: 209-218. PMID: 11157315, DOI: 10.1093/ajcn/73.2.209.Peer-Reviewed Original ResearchConceptsAge-related macular degenerationRisk of AMDTotal fat intakeFat intakeRelative riskHealth StudyPooled multivariate relative risksDiagnosis of AMDFish/wkModest inverse relationServings/moHealth Professionals FollowMultivariate relative riskNurses' Health StudyFood frequency questionnaireProfessionals FollowStudy of participantsProspective followVisual lossProspective studyLowest quintileDietary fatMacular degenerationHigh intakeLinolenic acid
1999
N‐acetyl transferase 2 genotypes, meat intake and breast cancer risk
Gertig D, Hankinson S, Hough H, Spiegelman D, Colditz G, Willett W, Kelsey K, Hunter D. N‐acetyl transferase 2 genotypes, meat intake and breast cancer risk. International Journal Of Cancer 1999, 80: 13-17. PMID: 9935222, DOI: 10.1002/(sici)1097-0215(19990105)80:1<13::aid-ijc3>3.0.co;2-w.Peer-Reviewed Original ResearchConceptsBreast cancer riskRed meat intakeMeat intakeRapid acetylatorsBreast cancerSlow acetylatorsCancer riskHealth StudyLow red meat intakeHigh red meat intakeNurses' Health StudyHeterocyclic aminesLack of associationHigh-temperature cooking methodsFrequent intakeNAT2 genotypeBlood drawAcetylator genotypeBlood samplesAcetylatorsSignificant associationCancerIntakeMajor causeHuman carcinogenesis