2023
Association between cancer stigma and cervical cancer screening uptake among women of Dhulikhel and Banepa, Nepal
Paneru B, Karmacharya A, Bharati A, Makaju S, Adhikari B, Kafle D, Shakya S, Spiegelman D, Seth S, Stangl A, Shrestha A, Shrestha A. Association between cancer stigma and cervical cancer screening uptake among women of Dhulikhel and Banepa, Nepal. PLOS ONE 2023, 18: e0285771. PMID: 37200234, PMCID: PMC10194964, DOI: 10.1371/journal.pone.0285771.Peer-Reviewed Original ResearchMeSH KeywordsCross-Sectional StudiesEarly Detection of CancerFemaleHealth Knowledge, Attitudes, PracticeHumansMass ScreeningNepalParityPregnancyUterine Cervical NeoplasmsConceptsCervical cancer screening uptakeCancer screening uptakeScreening uptakeMultivariable logistic regressionCancer Stigma ScaleCancer stigmaCervical cancerAge of menarcheFirst sexual intercourseLogistic regressionNepalese womenSexual intercourseReproductive health variablesCervical cancer screeningEffective screening programsSemi-urban areasCross-sectional studyPercent of womenMean total scoreFamily planning usersScreening servicesCancer screeningCommon cancerDisease burdenScreening program
2021
Impact of the Affordable Care Act on Colorectal Cancer Incidence and Mortality
Lee C, Kushi LH, Reed ME, Eldridge EH, Lee JK, Zhang J, Spiegelman D. Impact of the Affordable Care Act on Colorectal Cancer Incidence and Mortality. American Journal Of Preventive Medicine 2021, 62: 387-394. PMID: 34763959, PMCID: PMC8863627, DOI: 10.1016/j.amepre.2021.08.025.Peer-Reviewed Original ResearchMeSH KeywordsAgedColorectal NeoplasmsCost SharingEarly Detection of CancerHumansIncidenceInsurance CoverageMiddle AgedPatient Protection and Affordable Care ActUnited StatesConceptsColorectal cancer-related mortalityColorectal cancer incidenceCancer-related mortalityColorectal cancer outcomesAffordable Care ActCancer incidenceColorectal cancerCancer outcomesCare ActKaiser Permanente Northern California membersHealth plansColorectal cancer screeningInterrupted time series designRace/ethnicityCancer screeningCalifornia membersPreventive servicesPrivate health insurancePocket costsMortalityTime series designIncidenceCost sharingCancerComparison groupAnalysis of Survival Among Adults With Early-Onset Colorectal Cancer in the National Cancer Database
Cheng E, Blackburn HN, Ng K, Spiegelman D, Irwin ML, Ma X, Gross CP, Tabung FK, Giovannucci EL, Kunz PL, Llor X, Billingsley K, Meyerhardt JA, Ahuja N, Fuchs CS. Analysis of Survival Among Adults With Early-Onset Colorectal Cancer in the National Cancer Database. JAMA Network Open 2021, 4: e2112539. PMID: 34132794, PMCID: PMC8209612, DOI: 10.1001/jamanetworkopen.2021.12539.Peer-Reviewed Original ResearchConceptsEarly-onset colorectal cancerOnset colorectal cancerNational Cancer DatabaseColorectal cancerAge 51Overall survivalCancer DatabaseIncidence of CRCCox proportional hazards regressionPrimary colorectal cancerKaplan-Meier analysisProportional hazards regressionAge 50 yearsAge 25 yearsAnalysis of survivalCohort studySurvival benefitHazards regressionUnadjusted analysesCancer incidenceMAIN OUTCOMEAge 35Survival advantageLower riskStage I
2020
Adjunctive testing by cytology, p16/Ki‐67 dual‐stained cytology or HPV16/18 E6 oncoprotein for the management of HPV16/18 screen‐positive women
Torres‐Ibarra L, Lorincz AT, Wheeler CM, Cuzick J, Hernández‐López R, Spiegelman D, León‐Maldonado L, Rivera‐Paredez B, Méndez‐Hernández P, Lazcano‐Ponce E, Salmerón J. Adjunctive testing by cytology, p16/Ki‐67 dual‐stained cytology or HPV16/18 E6 oncoprotein for the management of HPV16/18 screen‐positive women. International Journal Of Cancer 2020, 148: 2264-2273. PMID: 33252834, DOI: 10.1002/ijc.33414.Peer-Reviewed Original ResearchMeSH KeywordsAdultEarly Detection of CancerFemaleHuman papillomavirus 16Human papillomavirus 18HumansKi-67 AntigenOncogene ProteinsPapillomavirus InfectionsConceptsHPV16/18-positive womenP16/KiLiquid-based cytologyHPV16/18-E6 oncoproteinColposcopy referralAdjunctive testingCervical intraepithelial neoplasia grade 2Dual-stained cytologyUnnecessary colposcopy referralsHigh-risk HPVCervical cancer screeningScreen-positive womenE6 oncoproteinCancer risk stratificationNormal cytologyPositive womenNonprogressive infectionRisk stratificationCervical cancerInvasive cancerCancer screeningDirect referralPositivity rateGrade 3Grade 2Impact of the Affordable Care Act on Colorectal Cancer Outcomes: A Systematic Review
Xu MR, Kelly AMB, Kushi LH, Reed ME, Koh HK, Spiegelman D. Impact of the Affordable Care Act on Colorectal Cancer Outcomes: A Systematic Review. American Journal Of Preventive Medicine 2020, 58: 596-603. PMID: 32008799, PMCID: PMC7175922, DOI: 10.1016/j.amepre.2019.11.018.Peer-Reviewed Original ResearchConceptsColorectal cancer screeningAffordable Care ActCancer screeningMedicaid expansionColorectal cancerCare ActNonsignificant increaseColorectal cancer morbidityColorectal cancer outcomesColorectal cancer incidenceStage of diagnosisAffordable Care Act's impactScreening ratesCancer outcomesCancer morbidityPrecancerous lesionsCancer incidenceNonsignificant decreaseEarly diagnosisMortality rateHealth outcomesSystematic reviewHealthcare accessRelevant studiesSignificant decrease