2004
Dairy Foods, Calcium, and Colorectal Cancer: A Pooled Analysis of 10 Cohort Studies
Cho E, Smith-Warner SA, Spiegelman D, Beeson WL, van den Brandt PA, Colditz GA, Folsom AR, Fraser GE, Freudenheim JL, Giovannucci E, Goldbohm RA, Graham S, Miller AB, Pietinen P, Potter JD, Rohan TE, Terry P, Toniolo P, Virtanen MJ, Willett WC, Wolk A, Wu K, Yaun SS, Zeleniuch-Jacquotte A, Hunter DJ. Dairy Foods, Calcium, and Colorectal Cancer: A Pooled Analysis of 10 Cohort Studies. Journal Of The National Cancer Institute 2004, 96: 1015-1022. PMID: 15240785, DOI: 10.1093/jnci/djh185.Peer-Reviewed Original ResearchMeSH KeywordsAdenomaAdultAgedAnimalsCalcium, DietaryCohort StudiesColorectal NeoplasmsDairy ProductsEatingEuropeFemaleHumansIncidenceMaleMiddle AgedMilkMultivariate AnalysisProportional Hazards ModelsProspective StudiesResearch DesignRisk AssessmentRisk FactorsSurveys and QuestionnairesUnited StatesConceptsColorectal cancerRelative riskMilk intakeCalcium intakeCohort studyPooled multivariable relative risksMultivariable relative risksFood frequency questionnaireColorectal cancer riskUsual dietary intakeConfidence intervalsDairy foodsFrequency questionnaireIncident casesDietary calciumPooled analysisLowest quintileInverse associationDietary intakeDistal colonEpidemiologic studiesCancer riskLower riskTotal calciumCancer
2000
Proportion of colon cancer risk that might be preventable in a cohort of middle-aged US men
Platz E, Willett W, Colditz G, Rimm E, Spiegelman D, Giovannucci E. Proportion of colon cancer risk that might be preventable in a cohort of middle-aged US men. Cancer Causes & Control 2000, 11: 579-588. PMID: 10977102, DOI: 10.1023/a:1008999232442.Peer-Reviewed Original ResearchConceptsColon cancer riskMiddle-aged US menRisk factorsCancer riskRisk scoreUS menPopulation attributable risk percentColon cancer risk factorsHealth Professionals FollowModifiable risk factorsAttributable risk percentCancer risk factorsColon cancer incidenceLow-risk scoresRed meat consumptionColon cancer casesLogistic regression modelsProfessionals FollowCigarette smokingColorectal neoplasiaColorectal cancerPhysical inactivityCancer incidenceCancer casesFamily history
1998
A prospective study of methylenetetrahydrofolate reductase and methionine synthase gene polymorphisms, and risk of colorectal adenoma.
Chen J, Giovannucci E, Hankinson SE, Ma J, Willett WC, Spiegelman D, Kelsey KT, Hunter DJ. A prospective study of methylenetetrahydrofolate reductase and methionine synthase gene polymorphisms, and risk of colorectal adenoma. Carcinogenesis 1998, 19: 2129-2132. PMID: 9886567, DOI: 10.1093/carcin/19.12.2129.Peer-Reviewed Original ResearchConceptsVal/Val polymorphismColorectal adenomasMethylenetetrahydrofolate reductase (MTHFR) geneHealth StudyProspective Nurses' Health StudyNurses' Health StudyRisk of adenomaVal polymorphismSynthase gene polymorphismsMethionine synthase geneLack of associationPolyp casesProspective studyColorectal cancerGly polymorphismBenign adenomasGene polymorphismsAdenomasColorectal tumorigenesisMalignant transformationFunctional polymorphismsMethylenetetrahydrofolate reductaseMethionine synthase gene polymorphismsRiskPolymorphism