2009
Intakes of Fruit, Vegetables, and Carotenoids and Renal Cell Cancer Risk: A Pooled Analysis of 13 Prospective Studies
Lee JE, Männistö S, Spiegelman D, Hunter DJ, Bernstein L, van den Brandt PA, Buring JE, Cho E, English DR, Flood A, Freudenheim JL, Giles GG, Giovannucci E, Håkansson N, Horn-Ross PL, Jacobs EJ, Leitzmann MF, Marshall JR, McCullough ML, Miller AB, Rohan TE, Ross JA, Schatzkin A, Schouten LJ, Virtamo J, Wolk A, Zhang SM, Smith-Warner SA. Intakes of Fruit, Vegetables, and Carotenoids and Renal Cell Cancer Risk: A Pooled Analysis of 13 Prospective Studies. Cancer Epidemiology Biomarkers & Prevention 2009, 18: 1730-1739. PMID: 19505906, PMCID: PMC2883186, DOI: 10.1158/1055-9965.epi-09-0045.Peer-Reviewed Original ResearchConceptsPooled multivariate relative risksRenal cell cancerMultivariate relative riskCell cancerRelative riskVegetable consumptionProspective studyPooled analysisStudy-specific relative risksRenal cell cancer riskCox proportional hazards modelFood frequency questionnaireIntake of fruitsLutein/zeaxanthinProportional hazards modelRandom-effects modelTotal vegetablesIncident casesLowest quintileVegetable intakeCancer riskHazards modelCancerTotal fruitRisk
2004
Fruit and Vegetable Intake and Risk of Major Chronic Disease
Hung HC, Joshipura KJ, Jiang R, Hu FB, Hunter D, Smith-Warner SA, Colditz GA, Rosner B, Spiegelman D, Willett WC. Fruit and Vegetable Intake and Risk of Major Chronic Disease. Journal Of The National Cancer Institute 2004, 96: 1577-1584. PMID: 15523086, DOI: 10.1093/jnci/djh296.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAnalysis of VarianceCardiovascular DiseasesCause of DeathChronic DiseaseConfidence IntervalsConfounding Factors, EpidemiologicDiet SurveysFeeding BehaviorFemaleFollow-Up StudiesFruitHealth PersonnelHumansIncidenceMaleMiddle AgedNeoplasmsProportional Hazards ModelsProspective StudiesResearch DesignRisk AssessmentRisk FactorsSurveys and QuestionnairesUnited StatesVegetablesConceptsMajor chronic diseasesVegetable intakeCardiovascular diseaseChronic diseasesRelative riskHealth StudyVegetable consumptionGreen leafy vegetable intakeSemiquantitative food frequency questionnaireCox proportional hazards analysisOverall cancer incidenceTotal fruitNurses' Health StudyFood frequency questionnaireProportional hazards analysisStrong inverse associationProspective cohortGreen leafy vegetablesHighest quintileInverse associationCancer incidenceFood groupsHealth professionalsOverall healthDietary information
2003
Fruits, vegetables and lung cancer: A pooled analysis of cohort studies
Smith‐Warner S, Spiegelman D, Yaun S, Albanes D, Beeson WL, van den Brandt PA, Feskanich D, Folsom AR, Fraser GE, Freudenheim JL, Giovannucci E, Goldbohm RA, Graham S, Kushi LH, Miller AB, Pietinen P, Rohan TE, Speizer FE, Willett WC, Hunter DJ. Fruits, vegetables and lung cancer: A pooled analysis of cohort studies. International Journal Of Cancer 2003, 107: 1001-1011. PMID: 14601062, DOI: 10.1002/ijc.11490.Peer-Reviewed Original ResearchConceptsLung cancer riskCancer riskVegetable consumptionLung cancerRelative riskLung cancer risk factorsStudy-specific relative risksIncident lung cancer casesTotal fruitCancer risk factorsLung cancer incidenceLung cancer casesTotal vegetable consumptionRandom-effects modelCohort studyCurrent smokersSmoking habitsProspective studyQuintiles 2Pooled analysisLowest quintileResidual confoundingInverse associationRisk factorsCancer incidence
2001
The effect of fruit and vegetable intake on risk for coronary heart disease.
Joshipura K, Hu F, Manson J, Stampfer M, Rimm E, Speizer F, Colditz G, Ascherio A, Rosner B, Spiegelman D, Willett W. The effect of fruit and vegetable intake on risk for coronary heart disease. Annals Of Internal Medicine 2001, 134: 1106-14. PMID: 11412050, DOI: 10.7326/0003-4819-134-12-200106190-00010.Peer-Reviewed Original ResearchConceptsCoronary heart diseaseHeart diseaseVegetable intakeGreen leafy vegetablesProtective effectHealth StudyVegetable consumptionFatal coronary heart diseaseStandard cardiovascular risk factorsVitamin CCardiovascular risk factorsNonfatal myocardial infarctionNurses' Health StudyProspective cohort studyFood frequency questionnaireIntake of fruitsRich fruitsMain outcome measuresApparent protective effectAssociation of fruitYears of ageConsumption of fruitsEffect of fruitConstituents of fruitsMen 40Intake of Fruits and Vegetables and Risk of Breast Cancer: A Pooled Analysis of Cohort Studies
Smith-Warner SA, Spiegelman D, Yaun SS, Adami HO, Beeson WL, van den Brandt PA, Folsom AR, Fraser GE, Freudenheim JL, Goldbohm RA, Graham S, Miller AB, Potter JD, Rohan TE, Speizer FE, Toniolo P, Willett WC, Wolk A, Zeleniuch-Jacquotte A, Hunter DJ. Intake of Fruits and Vegetables and Risk of Breast Cancer: A Pooled Analysis of Cohort Studies. JAMA 2001, 285: 769-776. PMID: 11176915, DOI: 10.1001/jama.285.6.769.Peer-Reviewed Original ResearchConceptsBreast cancer casesBreast cancerRelative riskCancer casesVegetable consumptionSpecific fruitsIncident invasive breast cancer casesIncident breast cancer casesStudy-specific relative risksInvasive breast cancer casesTotal fruitIntake of fruitsUsual dietary intakeBreast cancer riskCase-control studyDiet assessment methodsRandom-effects modelCohort studyTotal vegetablesExposure definitionGroup intakesProspective studyGreen leafy vegetablesPooled analysisDietary intake