2024
Improving lifestyle behaviors during chemotherapy for breast cancer: The Lifestyle, Exercise, and Nutrition Early After Diagnosis (LEANer) Trial
Puklin L, Ferrucci L, Harrigan M, McGowan C, Zupa M, Cartmel B, Li F, Ligibel J, Spiegelman D, Sharifi M, Sanft T, Irwin M. Improving lifestyle behaviors during chemotherapy for breast cancer: The Lifestyle, Exercise, and Nutrition Early After Diagnosis (LEANer) Trial. Cancer 2024, 130: 2440-2452. PMID: 38470431, PMCID: PMC11214600, DOI: 10.1002/cncr.35280.Peer-Reviewed Original ResearchPhysical activityDiet qualityHEI-2015Strength trainingLifestyle behaviorsHealthy Eating Index (HEI)-2015Breast cancerAssociated with baseline fatigueImprove physical activityImprove lifestyle behaviorsHigher HEI-2015Associated with higher oddsExercise interventionUsual careIntervention armIntervention groupBaseline fatigueLifestyle interventionYearlong interventionLower fatigueHigher oddsSecondary analysisLogistic regressionNewly diagnosed patientsStudy arms
2022
Effectiveness of a community-based education and peer support led by women’s self-help groups in improving the control of hypertension in urban slums of Kerala, India: a cluster randomised controlled pragmatic trial
Suseela R, Ambika R, Mohandas S, Menon J, Numpelil M, Vasudevan B, Ved R, Danaei G, Spiegelman D. Effectiveness of a community-based education and peer support led by women’s self-help groups in improving the control of hypertension in urban slums of Kerala, India: a cluster randomised controlled pragmatic trial. BMJ Global Health 2022, 7: e010296. PMID: 36384950, PMCID: PMC9670931, DOI: 10.1136/bmjgh-2022-010296.Peer-Reviewed Original ResearchConceptsMean systolic BPSystolic BPControl armIntervention armPragmatic trialUrban slumsTarget blood pressure goalsMajor public health problemBlood pressure goalsSelf-help group membersControl of hypertensionStandard of carePublic health problemPrimary healthcare systemSelf-help groupsCommunity-based educationPeer support programAntihypertensive medicationsUncontrolled hypertensionUsual careHypertension managementPrimary outcomeHypertensionHealthy behaviorsHealth problems